Etude de la Reactivite d'Oxo-4 tetrahydro-4,5,6,7 benzofurannes. I. Acces aux Furo [2,3-c]-acridines par Condensation de 1'Isatine et de 1'Acide Anthranilique
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概要
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Par condensation de cetones α-halogenes sur la dihydroresorcine, nous avons synthetise les furocyclanones suivantes : methyl-2-(Ia), dimethyl-2,3-(Ib), methyl-3-(Ic) et phenyl-2-(Id) oxo-4 tetrahydro-4,5,6,7 benzofurannes. La structure de Id, compose non encore decrit jusqu'ici, a ete etablie a partir des spectres de RMN, des spectres infrarouges et de quelques proprietes chimiques. Les furocyclanones Ia et Id peuvent etre condensees sur 1'isatate de potassium ou sur 1'acide anthranilique pour donner des derives originaux de la dihydro-4,5 furo [2,3-c] acridine, tandis que les furocyclanones Ib et Ic ne conduisent pas aux derives furoacridiniques attendus.
- 公益社団法人日本薬学会の論文
- 1971-06-25
著者
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高木 要
Central Research Laboratories, Zeria Pharmaceutical Co., Ltd.
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高木 要
Central Research Laboratories Zeria Pharmaceutical Co. Ltd.
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高木 要
Faculte des Sciences Pharmaceutiques, Universite Kitasato
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上田 武雄
Faculte des Sciences Pharmaceutiques, Universite Kitasato
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上田 武雄
School Of Pharmaceutical Sciences Kitasato University
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