Syntheses of Pyrimidinylhydrazones of 4-Biphenylylglyoxal
スポンサーリンク
概要
- 論文の詳細を見る
To search for antimicrobial agent, 2-hydrazino-4-alkoxy-6-methylpyrimidine, 2-hydrazino-4-alkylthio-6-methylpyrimidine, and 2-alkylthio-4-hydrazino-6-methylpyrimidine were synthesized by the hydrazination of the corresponding 2-chloro- and 4-chloropyrimidine with hydrazine hydrate, and it was found that chlorine atom at 2-position or 4-position in pyrimidine ring, is more reactive on hydrazine than alkylthio and alkoxy group at 4- or 2-position. These hydrazinopyrimidines of the three series were converted into pyrimidinylhydrazones of 4-biphenylylglyoxal by the condensation with 4-biphenylylglyoxal.
- 公益社団法人日本薬学会の論文
- 1963-11-25
著者
-
上田 武雄
Pharmaceutical Institute, Keio-Gijuku University
-
高木 要
Central Research Laboratories Zeria Pharmaceutical Co. Ltd.
-
高木 要
Pharmaceutical Institute, Keio-Gijuku University
関連論文
- Sur les Possibilites de Formation de Pyrimidines a partir de la Dibromo-3,4 dihydro-3,4 coumarine
- Syntheses and Antiviral Effect of p-Alkylbenzenesulfonamide Derivatives
- Reaction of 1,1-(2,2'-Oxydiethyl) biguanide with Dicyanodiamide.
- Reaction of 1,1-(2,2'-Oxydiethyl) biguanide with Dicyanodiamide.
- Synthesis of New Pyrimidine Derivatives from 2-Methyl-3-nitro- and 3-Amino-2-methylchromones
- Synthesis and Some Reactions of 6- (2-Hydroxyphenyl) -2-thiouracils
- Syntheses and Antiviral Activity of 3-Thioxo-6-aryl-3,4-dihydro-as-triazin-5 (2H)-one and 6-Aryl-as-triazine-3,5 (2H, 4H)-dione.
- Synthesis and Antiviral Effect of Hexahydro-s-triazines.
- Synthesis of Bisfurazanobenzo-2,1,3-thiadiazole and Related Compounds
- Synthesis and Reaction of Furazanobenzothiadiazole and Related Compounds
- Ring Transformation of 4-Amino-1H-1,5-benzodiazepine-3-carbonitrile. II. Formation of Ring-opened Hydrazine Adducts
- Ring Transformation of 4-Amino-1H-1,5-benzodiazepine-3-carbonitrile. The Use of Hydroxylamines as Nucleophile
- Reaction of Ethoxymethylenemalononitrile with 2-Aminopyridines
- Inhibitory Effect of Guanidine on Several Viruses Including Polio and Measles.
- Reaction of Ethoxymethylenemalononitrile with Hydrazine Hydrate
- Reaction of ο-Aminobenzamide Derivatives with Ethoxymethylenemalononitrile and Its Analogue
- Sur la Transformation de Derives Oxadiazoliques en Oxo-4 quinazolines par Hydrogenation Catalytique
- Sur la Formation d'Oxadiazoles-1,2,4 par Action de Benzamidoximes sur des Anhydrides Isatoiques
- Sur la Formation d'un Derive Pyrazolique Original a partir d'Hydrazine et d'Ethoxymethylene Malononitrile
- 核置換アルキルエフェドリン及びp-アルキルノルエフェドリンの合成研究
- Researches on Chemotherapeutic Drugs against Viruses. XII. : Syntheses and Antiviral Effects of 3-Alkylphenylazo-4-hydroxynaphthalenesulfonic Acid and Its Sulfonamide Derivatives.
- Researches on Chemotherapeutic Drugs against Viruses. XI. : Syntheses and Antiviral Effects of 3-Alkylphenylazo-4-aminonaphthalenesulfonic Acid and Its Sulfonamide Derivatives.
- Studies on Pyridazine Derivatives. IV. N-Oxidation of 3-Aminopyridazine and Its Ring Substitutes.
- Studies on Pyridazine Derivatives. III. Improved Synthetic Method of 3-Sulfanilyl-6-alkoxypyridazine.
- Studies on Pyridazine Derivatives. II. Synthesis of 6-Substituted 3-(p-Nitrophenyl)-, 3-(p-Tolyl)- and 3-(p-Aminomethylphenyl) sulfonamidopyridazines.
- Studies on Pyridazine Derivatives. I. Synthesis and Antimicrobial Activity of 6-Substituted 3-Aminopyridazine and its Sulfonamido Derivatives.
- Researches on Chemotherapeutic Drugs against Viruses. XXXI. Synthesis and Antiviral Effect of 3-(Alkoxyphenoxy)-1,2-propanediols on Respiratory Virus.
- Studies on Electrolytic Reduction of Streptomycin.
- Antiviral Effect and Syntheses of 4-Amino-6-alkylamino-s-triazine-2-carboxylic Acid Derivatives. Researches on Chemotherapeutic Drugs against Viruses. XXXVI.
- The Accelerating Effect of Arginine on Cytophatic Effect of Adeno Virus.
- Researches on Chemotherapeutic Drugs against Viruses. XXV. Studies on the Syntheses and Antiviral Effect of 2-Dimethylaminoethyl Alkylphenyl Ethers
- Researches on Chemotherapeutic Drugs against Viruses. XXIV. Studies on the Syntheses and Antiviral Effect of 2-Alkylphenoxyalkanoic Acids
- N-Alkylephedrine並びにアンモニウム塩の合成及び薬理作用について
- 砒素系化学療法剤の研究(第14報) : 有機砒素化合物の抗菌作用機序の研究その1
- Researches on Quaternary Ammonium Salts as Chemotherapeutic Drugs. I. : Syntheses of Trialkyl-p-alkylanilinium Salts.
- Researches on Chemotherapeutic Drugs against Viruses. XVI. : Chemotherapeutic Effect of N^1-Dodecanoyl-N^4-acetylaminonaphthalenesulfonamide-(1) on Neurotropic Viruses.
- Researches on Chemotherapeutic Drugs against Viruses. XIV. : Syntheses of several Quinolinium and Pyridinium Anionides.
- Synthesis of N-Alkyl-4-morpholinecarboxamidine.
- Synthesis of 3-(Guaiazulen-3-yl)-3-oxopropionic Acid Derivatives
- Synthese de Pyrimidines et de Pyrazoles a partir d'Acyl-3 halogeno-5 benzofurannes
- Sur Quelques Proprietes du Phenyl-2 formyl-3 benzofuranne
- Etude de la Reactivite d'Oxo-4 tetrahydro-4,5,6,7 benzofurannes. III. Sur la Formation de Furoacridines a partir du p-Bromophenyl-2 oxo-4 tetrahydro-4,5,6,7 benzofuranne
- Etude de la Reactivite d'Oxo-4 tetrahydro-4,5,6,7 benzofurannes. II. Acces aux Furoacridines par Application de la Reaction de Friedlaender
- Etude de la Reactivite d'Oxo-4 tetrahydro-4,5,6,7 benzofurannes. I. Acces aux Furo [2,3-c]-acridines par Condensation de 1'Isatine et de 1'Acide Anthranilique
- Sur la Formation des 8-Triazines par Action de Biguanides sur l'Ethoxymethylene Acetoacetate d'Ethyle ou sur l'Ethoxymethylene Malonate d'Ethyle
- Syntheses and Antiviral Effects of 3-Amino-6-alkyl-as-triazin-5-ol Derivatives.
- Syntheses of 4,6-Diamino-s-triazine-2-carboxamide Derivatives.
- Studies on Syntheses of Dimethylated Ephedrine Derivatives.
- Chemotherapeutic Arsenical Drugs. XIII. : Syntheses of sym-Triazine Derivatives of Diphenylarsinic Acids and Diphenylarsinous Acids.
- Syntheses of 2-Substituted-4,6-diamino-8-triazines
- Syntheses of Aminoalkylguanidine Derivatives.
- Syntheses of 2-Guanidino-2-methylpropylamine Derivatives
- The Direct Thiation of Pyrimidinol Derivatives.
- Synthesis and Antimicrobial Activity of 1-Acyl-2-sulfanilyhydrazine and 1-Acyl-2-(4-amino-1-naphthylsulfonyl) hydrazine.
- Aresenical Chemotherapeutic Drugs. XII. : Antibacterial Properties of Diarylthioarsinites.
- Arsenical Chemotherapeutic Drugs. XI. : Antibacterial Properties of Diarylarsinic Acids and Diarylarsinous Acids.
- Arsenical Chemotherapeutic Drugs. X. : Antibacterial Properties of Arylarsonic Acids and Arylarsonous Acids.
- Syntheses and Antiviral Effect of (Amidinocarbamoyl) pyridine Derivatives
- Reaction of 1-Substituted Biguanide with Diethyl Formylsuccinate and Diethyl Succinate.
- Syntheses of Pyrimidinylhydrazones of 4-Biphenylylglyoxal
- Studies on Anthelmintics. I. : Studies on Hydroxytetralin as an Anthelmintic.
- Syntheses of 3-Aminopropylguanidine Derivatives