The Direct Thiation of Pyrimidinol Derivatives.
スポンサーリンク
概要
- 論文の詳細を見る
The replacement of 4-hydroxyl group of aminopyrimidinols by sulfhydryl in one step, through the action of phosphorus pentasulfide in triethylamine or 3-picoline. 5-Acylamino-6-amino-4-pyrimidinols were treated with phosphorus pentasulfide in pyridine, to yield thiazolo [5,4-d] pyrimidine and 6-purinethiol compounds. The yield of both two type compounds were changed according to a functional group in the starting substance. These products, in addition, other 6-purinethiol and related compounds were screened as to their antiviral activities on poliomyelitis virus. Any of the compounds, however, did not exert a significant activity on the virus.
- 公益社団法人日本薬学会の論文
- 1963-07-25
著者
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上田 武雄
Pharmaceutical Institute, Keio-Gijuku University
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辻 忠和
Department Of Chemistry Japan Women's University
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辻 忠和
Pharmaceutical Institute Keio-gijuku University
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百名 弘子
Pharmaceutical Institute, Keio-Gijuku University
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百名 弘子
Pharmaceutical Institute Keio-gijuku University
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