Synthesis and Antimicrobial Activity of 1-Acyl-2-sulfanilyhydrazine and 1-Acyl-2-(4-amino-1-naphthylsulfonyl) hydrazine.

スポンサーリンク

概要

• 論文の詳細を見る

• 1-Acyl-2-sulfanilylhydrazine, 1-acyl-2-(4-amino-1-naphthylsulfonyl) hydrazine and their acyl derivatives were synthesized and their antimicrobial activity was examined. Among the derivatives of 1-acyl-2-sulfanilylhydrazine series, several compounds showed a weak in vitro activity on tubercle bacilli, but none of the compounds exerted any antibacterial or antiviral activity. On the contrary, there were found one compound having activity against tubercule bacilli comparable to that of INAH and dihydrostreptomycin, and two compounds having in vivo effect on Japanese B encephalitis virus equal to that of N-(4-amino-1-naphthylsulfonyl) dodecanamide, among the derivatives of 1-acyl-2-(4-amino-1-naphthylsulfonyl) hydrazine, but none of the compounds showed any activity against Escherichia coli communi or Staphylococcus aureus.

• 公益社団法人日本薬学会の論文
• 1962-03-25

著者

• 上田 武雄

  Pharmaceutical Institute, Keio-Gijuku University

• 辻 忠和

  Department Of Chemistry Japan Women's University

• 辻 忠和

  Pharmaceutical Institute Keio-gijuku University

• 中田 多嘉

  Pharmaceutical Institute, Keio-Gijuku University

• 中田 多嘉

  Pharmaceutical Institute Keio-gijuku University

関連論文

• Syntheses and Antiviral Effect of p-Alkylbenzenesulfonamide Derivatives
• Reaction of 1,1-(2,2'-Oxydiethyl) biguanide with Dicyanodiamide.
• Reaction of 1,1-(2,2'-Oxydiethyl) biguanide with Dicyanodiamide.
• Syntheses and Antiviral Activity of 3-Thioxo-6-aryl-3,4-dihydro-as-triazin-5 (2H)-one and 6-Aryl-as-triazine-3,5 (2H, 4H)-dione.
• Syntheses and Antimicrobial Activity of 5-Alkyl-2-thiouracil Derivatives.
• Synthesis and Antiviral Effect of Hexahydro-s-triazines.
• Synthesis and Antimicrobial Activity of N^1-(2-Alkylthio-6-alkoxy-4-pyrimidinyl) sulfanilamide.
• Conformational Analysis of 1,3-Diethyl-5-methyl-5-nitrohexahydropyrimidine
• The Reaction of Ethyl 3-Chloropropionimidate with Amino Heterocycles
• Synthesis of 2-Substituted-6-amino-4,5-dihydropyrimidine
• Syntheses of 2-Acylaminoacetamidine and 3-Acylaminopropionamidine Derivatives
• Inhibitory Effect of Guanidine on Several Viruses Including Polio and Measles.
• 核置換アルキルエフェドリン及びp-アルキルノルエフェドリンの合成研究
• Syntheses and Reactions of 3-Amino-4 (3H)-pyrimidones
• Researches on Chemotherapeutic Drugs against Viruses. XII. : Syntheses and Antiviral Effects of 3-Alkylphenylazo-4-hydroxynaphthalenesulfonic Acid and Its Sulfonamide Derivatives.
• Researches on Chemotherapeutic Drugs against Viruses. XI. : Syntheses and Antiviral Effects of 3-Alkylphenylazo-4-aminonaphthalenesulfonic Acid and Its Sulfonamide Derivatives.
• Studies on Pyridazine Derivatives. IV. N-Oxidation of 3-Aminopyridazine and Its Ring Substitutes.
• Studies on Pyridazine Derivatives. III. Improved Synthetic Method of 3-Sulfanilyl-6-alkoxypyridazine.
• Studies on Pyridazine Derivatives. II. Synthesis of 6-Substituted 3-(p-Nitrophenyl)-, 3-(p-Tolyl)- and 3-(p-Aminomethylphenyl) sulfonamidopyridazines.
• Studies on Pyridazine Derivatives. I. Synthesis and Antimicrobial Activity of 6-Substituted 3-Aminopyridazine and its Sulfonamido Derivatives.
• Researches on Chemotherapeutic Drugs against Viruses. XXXI. Synthesis and Antiviral Effect of 3-(Alkoxyphenoxy)-1,2-propanediols on Respiratory Virus.
• Studies on Electrolytic Reduction of Streptomycin.
• Antiviral Effect and Syntheses of 4-Amino-6-alkylamino-s-triazine-2-carboxylic Acid Derivatives. Researches on Chemotherapeutic Drugs against Viruses. XXXVI.
• The Accelerating Effect of Arginine on Cytophatic Effect of Adeno Virus.
• Researches on Chemotherapeutic Drugs against Viruses. XXV. Studies on the Syntheses and Antiviral Effect of 2-Dimethylaminoethyl Alkylphenyl Ethers
• Researches on Chemotherapeutic Drugs against Viruses. XXIV. Studies on the Syntheses and Antiviral Effect of 2-Alkylphenoxyalkanoic Acids
• N-Alkylephedrine並びにアンモニウム塩の合成及び薬理作用について
• 砒素系化学療法剤の研究(第14報) : 有機砒素化合物の抗菌作用機序の研究その1
• Researches on Quaternary Ammonium Salts as Chemotherapeutic Drugs. I. : Syntheses of Trialkyl-p-alkylanilinium Salts.
• Researches on Chemotherapeutic Drugs against Viruses. XVI. : Chemotherapeutic Effect of N^1-Dodecanoyl-N^4-acetylaminonaphthalenesulfonamide-(1) on Neurotropic Viruses.
• Researches on Chemotherapeutic Drugs against Viruses. XIV. : Syntheses of several Quinolinium and Pyridinium Anionides.
• Synthesis of N-Alkyl-4-morpholinecarboxamidine.
• Syntheses and Reactions of N-Aminothiouracils and Thiadiazolo [3,2-α] pyrimidinones
• Urazole及びその関連化合物の合成及び抗ウィールス性 : 上田豊島 : 抗ウィールス性化学療法剤に関する研究 第17報
• Syntheses and Antiviral Effects of 3-Amino-6-alkyl-as-triazin-5-ol Derivatives.
• Syntheses of 4,6-Diamino-s-triazine-2-carboxamide Derivatives.
• Studies on Syntheses of Dimethylated Ephedrine Derivatives.
• Chemotherapeutic Arsenical Drugs. XIII. : Syntheses of sym-Triazine Derivatives of Diphenylarsinic Acids and Diphenylarsinous Acids.
• Synthesis of Two Amidine Derivatives by the Vilsmeier-Haack Reaction of 3-Amino-4(3H)-oxo-2(1H)-pyrimidinethione and Their Conversion into 5H-1,3,4-thiadiazolo [3,2-a] pyrimidin-5-ones
• On the Air Oxidation of 5-Amino-1,3-dialkyl-5-methylhexahydropyrimidines
• Cupric Ion Catalyzed Guanidide Hydrolysis
• The Stereochemistry of the Quaternization of 5-Methyl-5-nitro-1,3-dialkylhexahydropyrimidines
• Syntheses of 2-Substituted-4,6-diamino-8-triazines
• Syntheses of Aminoalkylguanidine Derivatives.
• Syntheses of 2-Guanidino-2-methylpropylamine Derivatives
• The Direct Thiation of Pyrimidinol Derivatives.
• Synthesis and Antimicrobial Activity of 1-Acyl-2-sulfanilyhydrazine and 1-Acyl-2-(4-amino-1-naphthylsulfonyl) hydrazine.
• Aresenical Chemotherapeutic Drugs. XII. : Antibacterial Properties of Diarylthioarsinites.
• Arsenical Chemotherapeutic Drugs. XI. : Antibacterial Properties of Diarylarsinic Acids and Diarylarsinous Acids.
• Arsenical Chemotherapeutic Drugs. X. : Antibacterial Properties of Arylarsonic Acids and Arylarsonous Acids.
• Syntheses and Antiviral Effect of (Amidinocarbamoyl) pyridine Derivatives
• Reaction of 1-Substituted Biguanide with Diethyl Formylsuccinate and Diethyl Succinate.
• Syntheses of Pyrimidinylhydrazones of 4-Biphenylylglyoxal
• Researches on Chemotherapeutic Drugs against Viruses. XXVII. Synthesis and Antiviral Activity of 1-(p-Alkylphenyl)-3-dimethylamino-1-propanol
• Studies on Anthelmintics. I. : Studies on Hydroxytetralin as an Anthelmintic.
• Syntheses of 3-Aminopropylguanidine Derivatives

もっと見る 閉じる

スポンサーリンク