Preparation and Hydrolysis of 4-Amino-1H-1,5-benzodiazepine-3-carbonitrile
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概要
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In the presence of hydrochloric acid, o-(2,2-dicyanovinyl) aminoaniline is easily converted into 4-amino-1H-1,5-benzodiazepine-3-carbonitrile, which can be hydrolyzed with various bases to other diazepine, triazepine or benzimidazole derivatives. Ethyl 4-amino-1H-1,5-benzodiazepine-3-carboxlate and other 1,5-benzodiazepine derivatives were also obtained from similar reactions. A remarkable tautomeric nature of compound (IX) is also reported.
- 公益社団法人日本薬学会の論文
- 1975-07-25
著者
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岡本 義久
School of Pharmaceutical Sciences, Kitasato University
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上田 武雄
School of Pharmaceutical Sciences, Kitasato University
-
岡本 義久
School Of Pharmaceutical Sciences Kitasato University
-
上田 武雄
School Of Pharmaceutical Sciences Kitasato University
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