Enantioselective Reaction of (±)-1-Hydroxy-5-methyl-3-vinylcyclohex-2-ene and Its Acyl Derivatives Using Lipid-Lipase Aggregates in Organic Solvent
スポンサーリンク
概要
- 論文の詳細を見る
The enzymatic esterification or hydrolysis of 1-hydroxy((±)-1), 1-acetoxy((±)-2) and 1-butyryloxy-5-methyl-3-vinylcyclohex-2-ene ((±)-3) was carried out using lipid-lipase aggrgates. The esterification of (±)-1 provided (1S, 5S)-1 with >99% ee using lipid-lipase "Amano P" with vinyl butyrate as the acylating reagent.
- 公益社団法人日本薬学会の論文
- 1996-04-15
著者
-
Shimizu Noriko
Kyoritsu University Of Pharmacy
-
Shimizu Nobuko
Pharmaceutical Institute School Of Medicine Keio University
-
Akita Hiroyuki
School Of Parmaceutical Sciences Toho University
-
KAWAMATA Takeshi
Pharmaceutical Institute, School of Medicine, Keio University
-
Kawamata T
Pharmaceutical Institute School Of Medicine Keio University
-
Kawamata Takeshi
Pharmaceutical Institute School Of Medicine Keio University
関連論文
- Enzymatic Hydrolysis of meso(syn-syn)-1,3,5-Triacetoxy-2,4-dimethylpentane and Acetylation of meso(syn-syn)-3-Benzyloxy-2,4-dimethylpentane-1,5-diol by Lipase
- A Synthesis of (2R, 4'R, 8'R)-α-Tocopherol (Vitamin E) Side Chain
- Synthesis of the Metabolites of 4-(2-Methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide (KRP-197/ONO-8025)
- Latifolosides K and L, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Latifolosides I and J, Two New Triterpenoid Saponins from the Bark of Ilex latifolia
- Characterization of Acetohexamide Reductases Purified from Rabbit Liver, Kidney, and Heart: Structural Requirements for Substrates and Inhibitors
- Purifiation and Catalytic Properties of a Novel Acetohexamide-Reducing Enzyme from Rabbit Heart
- Synthesis of Decalin Type Chiral Synthons Base on Enzymatic Function
- Enantioselective Synthesis of (2R, 4'R, 8'R)-α-Tocopherol (Vitamin E) Based on Enzymatic Function
- Ardisimamillosides G and H, Two New Triterpenoid Saponins from Ardisia mamillata
- Ardisimamillosides C-F, Four New Triterpenoid Saponins from Ardisia mamillata
- Reaction of Methyl 4,5-Epoxy-(2E)-pentenoate with Arylcopper Reagents
- Chemoenzymatic Synthesis of Sacranosides A and B
- Chemoenzymatic Synthesis of Naturally Occurring Benzyl 6-O-Glycosyl-β-D-glucopyranosides
- Simple Synthesis of β-D-Glycopyranosides Using β-Glycosidase from Almonds
- Five New Triterpenoid Saponins from the Roots of Platycodon grandiflorum
- Synthetic Study of Piericidins. II. Synthesis of Piericidin Analogues
- Synthetic Study of Piericidins. I. Synthesis of the Side Chain of Piercidin B_1
- Influence of N-Terminal Peptide and Oligosaccharide on the Clearance of t-PA
- Determination of the Absolute Stereostructure of seco-Macrosphelide E Produced by a Fungal Strain from a Sea Hare
- Concise Syntheses of Cystothiazoles A, C, D, and Melithiazol B
- Enzymatic Synthesis of (-)- and (+)-Acetoxyhexamides and (-)- and (+)-Hydroxyhexamides
- New A-Ring Lactone Triterpenoid Saponins from the Roots of Platycodon grandiflorum
- Studies on the chemical constituents from the roots of Platycodon grandiflorum
- Six New Dammarance-type Triterpene Saponins from the Leaves of Panax ginseng
- β_1-Adrenergic receptor mediation in the lichen glucan PB-2-induced enhancement of long-term potentiation in the rat dentate gyrus in vivo
- Further Studies on the Structure of Polysaccharides from the Lichen Flavoparmelia caperata (L.) HALE
- Influence of Sugar Chain on Fibrin Affinity of Recombinat t-PA
- The Reaction of (4R, 5R)-and (4S, 5S)-4, 5-Epoxy-2(E)-Hexenoates and Secondary Amines
- An Amphiphile-Lipase Aggregate Bearing 1,2-Dialkylated Mannitol Ether as a New Type of Immobilized Enzyme in Organic Solvents
- Simple Approach to Optically Active Drimane Sesquiterpenes Based on Enzymatic Resolution
- Enzymatic Hydrolysin in Organic Solvents for Kinetic Resolution of Water-Insoluble α-Acyloxy Esters with Immobilized Lipases
- Synthesis of (R)-Curcumene and (R)-Xanthorrizol Based on 1,2-Aryl Migration via Phenonium Ion
- Solvolysis of (4,5)-anti-4-Aryl-5-tosyloxy-2(E)-hexenoate Derivatives
- Enzymatic Resolution of (±)-5-Acetoxy-4-aryl-(2E)-pentenoate Derivatives
- Two New Diterpenoids from Plectranthus nummularius BRIQ.
- Cytotoxic Factor Induced in Murine Serum After Intravenous Administration of a Dehydrogenation Polymer of p-Coumaric Acid (A Synthetic Lignin)
- Characterization of a Cytotoxic Factor Induced in Murine Serum after the Intravenous Administration of Dehydrogenation Polymers of Phenylpropenoids (a Class of Synthetic Lignins)
- Enhanced Cytotoxicity of Alkyl Viologens and N, N'-Diamino Analogs toward Cultured Murine Leukemia L1210 Cells under Vortex-Stirring with a High Molecular Weight Polyacrylic Acid
- Synthesis of Methyl 1-O-(4-Hydroxymethamphetaminyl)-α-D-glucopyranouronate
- (1-Ethoxyvinyl)lithium in the Total Synthesis of Thymine Polyoxin C and Uracil Polyoxin C
- Chemoenzymatic Synthesis of n-Hexyl and ο-β-D-Xylopyranosyl-(1→6)-β-D-glucopyranosides
- First Synthesis of (+)-α-and (+)-γ-Polypodatetraenes
- Stereoselective Synthesis of 4'-α-Alkylcarbovir Derivatives Based on an Asymmetric Synthesis or Chemoenzymatic Procedure
- Total Synthesis of(S)-(+)-Curcudiol, and(S)-(+)-and(R)-(-)-Curcuphenol
- Formal Total Synthesis of (+)-Macrosphelide A Based on Regioselective Hydrolysis Using Lipase
- Chemoenzymatic Synthesis of (+)-α-Polypodatetraene and Methyl (5R,10R,13R)-Labda-8-en-15-oate
- Enantioselective Reaction of (±)-1-Hydroxy-5-methyl-3-vinylcyclohex-2-ene and Its Acyl Derivatives Using Lipid-Lipase Aggregates in Organic Solvent
- Studies on the constituents of Leonotis nepetaefolia
- Determination of the Absolute Structure of (+)-Cystothiazole B
- Triterpenoids from stem bark of Ilex latifolia(Natural Medicine Note)
- Studies on the constituents of Leonotis nepetaefolia
- Identification of Sesquiterpenoid Constituents in the Essential Oil of Curcuma wenyujin by Capillary Gas Chromatographic Mass Spectrometry
- Studies on Non-Sesquiterpenoid Constituents of Gaillardia pulchella. I. : Highly Lipophilic Substances, Higher Primary Alkanols
- A short-step synthetic approach to eudesmane skeleton. A synthesis of (.+-.)-.BETA.-eudesmol and related eudesmane sesquiterpenes.
- Determination of Stereostructure of Neocurdione Isolated from Curcuma wenyujin