Total Synthesis of(S)-(+)-Curcudiol, and(S)-(+)-and(R)-(-)-Curcuphenol
スポンサーリンク
概要
- 論文の詳細を見る
A highly enantioselective synthesis of the versatile chiral synthons possessing one stereogenic center, (S)-and(R)-4-aryl-5-hydroxy-(2E)-pentenoate(3)was achieved based on the enzymatic reaction of (±)-3 with commercially available lipases MY-30 or OF-360 from Candida rugosa. Application of(S)-3 and(R)-3 to the total syntheses of(S)-curcuphenol(1), (S)-curcudiol(2), and(R)-curcuphenol(1), respectively, is described.
- 公益社団法人日本薬学会の論文
- 2001-12-01
著者
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Akita Hiroyuki
School Of Parmaceutical Sciences Toho University
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Ono Machiko
School Of Pharmaceutical Sciences Toho University
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OGURA Yuuko
School of pharmaceutical Sciences, Toho University
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HATOGAI Kazumi
School of pharmaceutical Sciences, Toho University
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Ogura Yuuko
School Of Pharmaceutical Sciences Toho University
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Hatogai Kazumi
School Of Pharmaceutical Sciences Toho University
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Ono Machiko
School Of Pharmaceutical Sciences International Univ. Of Health And Welfare
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