A Synthesis of (2R, 4'R, 8'R)-α-Tocopherol (Vitamin E) Side Chain

概要

論文の詳細を見る
Optically pure (3R, 7R)-3,7,11-trimethyldodecan-1-ol (16), corresponding to the α-tocopherol side chain, was synthesized by the coupling reaction of a chiral isoprene unit (3S)-9 derived from an enzymatically hydrolyzed product (2S, 3S)-2 and a ten-carbon alkylating reagent (R)-13 derived from (R)-(+)-pulegone.
社団法人日本薬学会の論文
1996-11-15

著者

関連論文

Enzymatic Hydrolysis of meso(syn-syn)-1,3,5-Triacetoxy-2,4-dimethylpentane and Acetylation of meso(syn-syn)-3-Benzyloxy-2,4-dimethylpentane-1,5-diol by Lipase
A Synthesis of (2R, 4'R, 8'R)-α-Tocopherol (Vitamin E) Side Chain
Synthesis of the Metabolites of 4-(2-Methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide (KRP-197/ONO-8025)
Characterization of Acetohexamide Reductases Purified from Rabbit Liver, Kidney, and Heart: Structural Requirements for Substrates and Inhibitors
Purifiation and Catalytic Properties of a Novel Acetohexamide-Reducing Enzyme from Rabbit Heart
Synthesis of Decalin Type Chiral Synthons Base on Enzymatic Function
Enantioselective Synthesis of (2R, 4'R, 8'R)-α-Tocopherol (Vitamin E) Based on Enzymatic Function
Reaction of Methyl 4,5-Epoxy-(2E)-pentenoate with Arylcopper Reagents
Chemoenzymatic Synthesis of Sacranosides A and B
Chemoenzymatic Synthesis of Naturally Occurring Benzyl 6-O-Glycosyl-β-D-glucopyranosides
Simple Synthesis of β-D-Glycopyranosides Using β-Glycosidase from Almonds
Inhibition of LysoPAF Acetyltransferase by the Ingredients from Lithospermum Root
Inhibition of LysoPAF Acetyltransferase Activity by Components of Licorice Root
Synthetic Study of Piericidins. II. Synthesis of Piericidin Analogues
Synthetic Study of Piericidins. I. Synthesis of the Side Chain of Piercidin B_1
Determination of the Absolute Stereostructure of seco-Macrosphelide E Produced by a Fungal Strain from a Sea Hare
Concise Syntheses of Cystothiazoles A, C, D, and Melithiazol B
Enzymatic Synthesis of (-)- and (+)-Acetoxyhexamides and (-)- and (+)-Hydroxyhexamides
The Reaction of (4R, 5R)-and (4S, 5S)-4, 5-Epoxy-2(E)-Hexenoates and Secondary Amines
An Amphiphile-Lipase Aggregate Bearing 1,2-Dialkylated Mannitol Ether as a New Type of Immobilized Enzyme in Organic Solvents
Simple Approach to Optically Active Drimane Sesquiterpenes Based on Enzymatic Resolution
Enzymatic Hydrolysin in Organic Solvents for Kinetic Resolution of Water-Insoluble α-Acyloxy Esters with Immobilized Lipases
Synthesis of (R)-Curcumene and (R)-Xanthorrizol Based on 1,2-Aryl Migration via Phenonium Ion
Solvolysis of (4,5)-anti-4-Aryl-5-tosyloxy-2(E)-hexenoate Derivatives
Enzymatic Resolution of (±)-5-Acetoxy-4-aryl-(2E)-pentenoate Derivatives
Synthesis of Methyl 1-O-(4-Hydroxymethamphetaminyl)-α-D-glucopyranouronate
(1-Ethoxyvinyl)lithium in the Total Synthesis of Thymine Polyoxin C and Uracil Polyoxin C
Chemoenzymatic Synthesis of n-Hexyl and ο-β-D-Xylopyranosyl-(1→6)-β-D-glucopyranosides
First Synthesis of (+)-α-and (+)-γ-Polypodatetraenes
Stereoselective Synthesis of 4'-α-Alkylcarbovir Derivatives Based on an Asymmetric Synthesis or Chemoenzymatic Procedure
Total Synthesis of(S)-(+)-Curcudiol, and(S)-(+)-and(R)-(-)-Curcuphenol
Formal Total Synthesis of (+)-Macrosphelide A Based on Regioselective Hydrolysis Using Lipase
Chemoenzymatic Synthesis of (+)-α-Polypodatetraene and Methyl (5R,10R,13R)-Labda-8-en-15-oate
Enantioselective Reaction of (±)-1-Hydroxy-5-methyl-3-vinylcyclohex-2-ene and Its Acyl Derivatives Using Lipid-Lipase Aggregates in Organic Solvent
Determination of the Absolute Structure of (+)-Cystothiazole B
CM-02 BANDING REDUCTION IN ELECTROPHOTOGRAPHIC PROCESSES THROUGH SPATITAL-SAMPLED LINEAR PARAMETER VARYING REPETITIVE CONTROL

A Synthesis of (2R, 4'R, 8'R)-α-Tocopherol (Vitamin E) Side Chain

スポンサーリンク

概要

著者

関連論文

スポンサーリンク