Metal-Containing Components in Medicinal Plants. III.Manganese-Containing Components in Theae Folium as Oral Magnetic Resonance Imaging Contrast Materials
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概要
- 論文の詳細を見る
A manganese-containing component from the water-extract of Theae folium (green tea) was found to exert an augmentative effect in magnetic resonance imaging (MRI) contrast and may possibly be a manganese(II) complex with a pectin-like polysaccharide capable of shortening the spin-lattice relaxation time (T_1) of water protons. Even though only the manganese(II) ion with S=5/2 is active in T_1-shortening ability, which should enhance contrast, complexation of this ion with the polysaccharide causes a marked increase in its activity. This manganese-containing pectin-like polysaccharides should prove useful as a low-toxic oral gastrointestinal contrast material in MRI.
- 公益社団法人日本薬学会の論文
- 1996-12-15
著者
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MINO Yoshiki
Department of Neurosurgery, Toyama Medical and Pharmaceutical University
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YAMADA Katsuki
Sakai Chemical Industry Co., Ltd.,
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NAGASAWA Osamu
Sakai Chemical Industry Co., Ltd.,
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Mino Y
Osaka Univ. Pharmaceutical Sci. Osaka Jpn
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Yamada K
Graduate School Of Pharmaceutical Sciences Kyushu University
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Mino Yoshiki
Department Of Environment Analysis Osaka University Of Pharmaceutical Sciences
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Nagasawa Osamu
Sakai Chemical Industry Co. Ltd.
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Yamada Katsuya
Graduate School Of Pharmaceutical Sciences Nagoya City University
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TAKEDA Toyonori
Sakai Chemical Industry Co., Ltd.,
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Takeda Toyonori
Sakai Chemical Industry Co. Ltd.
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