Lewis Acid-Promoted Alkylations of Arenes and 1-Trimethylsilylalkynes with β-Chloro-β-thiopropanoic Esters

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概要

• 論文の詳細を見る

• Ethyl 3-chloro-3-(3,4-dichlorophenylthio)propanoate (8) reacted with electron-rich arenes in the presence of titanium tetrachloride to give the Friedel-Crafts products 10a-13a. Reactions of 8 with 1-trimethylsilylalkynes 14a-d were effected with aluminum chloride to afford the substitution products 15a-d. Some chemical transformations of the products are also described.

• 社団法人日本薬学会の論文
• 1991-05-25

著者

• 池田 正澄

  Kyoto Pharmaceutical University

• 池田 正澄

  京都薬科大学

• 石橋 弘行

  Kyoto Pharmaceutical University

• 石橋 弘行

  金沢大学薬学部

• 石橋 弘行

  京都薬科大学

• 三野 真美

  Kyoto Pharmaceutical University

• 阪田 まなつ

  Kyoto Pharmaceutical University

• 稲田 篤彦

  Kyoto Pharmaceutical University

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