A New, Convenient Route to Erbstatin and N-Acetyl-1,2-didehydrodopamine

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概要

• 論文の詳細を見る

• Erbstatin dimethyl ether (12) was synthesized by Friedel-Crafts reaction of chloro(methyl- or phenyl-thio)acetonitrile (5a or 5b) with hydroquinone dimethyl ether, followed by reduction to the amine, formylation, and oxidative desulfenylation. By using a similar sequence of reactions, N-acetyl-1,2-didehydrodopamine dimethyl ether (13) was prepared from veratrole and 5a, b.

• 社団法人日本薬学会の論文
• 1989-08-25

著者

• 岡野 昌彦

  Kyoto Pharmaceutical University

• 見理 剛

  Kyoto Pharmaceutical University

• 池田 正澄

  Kyoto Pharmaceutical University

• 池田 正澄

  京都薬科大学

• 石橋 弘行

  Kyoto Pharmaceutical University

• 石橋 弘行

  金沢大学薬学部

• 石橋 弘行

  京都薬科大学

• 高室 巌

  Kyoto Pharmaceutical University

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