Synthesis of 3-Carboxyceph-3-em Compounds and Reactions of Cephalosporin Thiolactones
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概要
- 論文の詳細を見る
Starting from cephalosporin thiolactones (1), a sequence of reactions (bromination, hydrolysis, oxidation and opening of the dioxo thiophene ring) yielded 3-carboxyceph-3-ems (10). Several reactions of thiolactone derivatives are also described.
- 公益社団法人日本薬学会の論文
- 1979-12-25
著者
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松尾 泰介
Central Research Division, Takeda Chemical Industries, Ltd.
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菅原 徹
Molecular Chemistry Laboratory, Takeda Chemical Industries Ltd.,
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三木 卓一
武田薬品工業株式会社中央研究所
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菅原 徹
Molecular Chemistry Laboratory Takeda Chemical Industries Ltd.
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菅原 徹
Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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桝屋 浩大
Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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松尾 泰介
Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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三木 卓一
Medicinal Research Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.
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桝屋 浩大
Central Research Division Takeda Chemical Ind. Ltd.
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