The Structure of Bottromycin A_2,a New Component of Bottromycins
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概要
- 論文の詳細を見る
Bottromycin A_2 is hydrolyzed to tetrapeptide and dipeptide by alkaline hydrolysis. The structures of both peptides are determined to be 3,3-dimethyl-2-aminobutylylvalyl-3-methylprolylglycine and 3-methyl-3-phenylalanyl-3-(2-thiazolyl)-β-alanine. Hydrochloric acid hydrolysis of bottromycin A_2 gives Δ^1-isocaproyltetrapeptide and the structure is discussed on the bases of pKa studies. The structure of bottromycin A_2 is proposed from the results above described.
- 社団法人日本薬学会の論文
- 1966-09-25
著者
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梅沢 浜夫
微化研
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中村 昭四郎
Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine
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梅沢 浜夫
Institute of Microbial Chemistry
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中村 昭四郎
広島大学医学部総合薬学科
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中村 昭四郎
Institute Of Applied Microbiology University Of Tokyo
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