Studies of Steroidal α-Amino Acids. I. Synthesis of Two Epimeric 3-Amino-5α-cholestane-3-carboxylic Acids and Their Configuration

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概要

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• Two epimeric 3-amino-5α-cholestane-3-carboxylic acids were synthesized by both the Strecker method and the Bucherer-hydantoin synthesis as shown in Chart 1. The configurations of these amino acids were established by comparing the hydrolysis rate of their methyl esters. Additionally, their configurations were also supported by some other data such as the pKa' values, mass spectra, and infrared spectra of their derivatives.

• 公益社団法人日本薬学会の論文
• 1965-12-25

著者

• 小畑 和永

  Gifu College Of Pharmacy

• 牧 敬文

  Gifu College Of Pharmacy

• 佐藤 誠

  森下ルセル株式会社総合研究所

• 佐藤 誠

  Gifu College of Pharmacy

• 佐藤 誠

  岐阜薬科大学

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