Studies of Alicyclic α-Amino Acids and Their Derivatives. V. Decyanization of Alicyclic α-Acetylaminonitriles with Sodium Borohydride
スポンサーリンク
概要
- 論文の詳細を見る
Upon treatment with sodium borohydride in pyridine, 1-acetylamino-cis-4-t-butyl-cyclohexane-1-carbonitrile, 2-acetylaminonorbornane-endo-2-carbonitrile and 2-acetyl-aminobornane-endo-2-carbonitrile underwent decyanization to give a mixture of isomeric acetylamino compounds in high yields, respectively. The product distribution can be explained in terms of the preferential attack of a hydride ion on the less-hindered side of the molecules.
- 公益社団法人日本薬学会の論文
- 1975-07-25
著者
関連論文
- Photochemical Synthesis of Condensed Triazole N-Oxide
- 転位反応の研究(第5報)ピリジン誘導体におけるスマイル転位(5)
- Studies of Rearrangement Reaction. VIII. Ring-Contraction from Pyridazinone Derivatives to Pyrazolone Derivatives. (3).
- New and Facile Synthesis of 5,6,7,8-Tetrahydro-5-deaza-5-thiapterins via the Aliphatic S-N Type Smiles Rearrangement
- The Dimroth Rearrangement of 6-Aminouracil Derivatives
- A NEWLY DEVISED METHOD FOR THE OXIDATIVE UNMASKING OF 1,N^6-ETHENO-ADENOSINES : FACILE CONVERSION OF ADENOSINE INTO 2-DEUTERATED ADENOSINE
- Facile Unmasking of Ethenylated Isocytosines via Diacetoxylation with Lead Tetraacetate
- First Synthesis of 5,6,7,8-Tetrahydro-8-deaza-8-thiafolic Acid
- Conversion of D-Glucose into the β-Hydroxy-δ-lactone Moiety of Mevinic Acids and Congeners via D-Idose as a Key Chiral Intermediate
- FACILE CONVERSION OF N^6-BENZOYLADENOSINES INTO 5'-CHLORO-5'-DEOXY-8-HYDROXYADENOSINES BY A REACTION WITH CUPRIC CHLORIDE : A PROMINENT SUBSTITUENT EFFECT OF THE N^6-BENZOYL GROUP
- A Novel Example of Thermal Oxygenation of Aromatic Hydrocarbons with a Heterocyclic N-Oxide : Unusual Reactivity of Pyrimido[5,4-g]pteridinetetrone 10-Oxide
- Photooxygenation of Polycyclic Aromatic Hydrocarbons by Pyrimido[5,4-g]pteridine N-Oxide
- PHOTO-OXYGENATION OF ALKANES BY A HETEROCYCLIC N__--OXIDE VIA NON-OXENE MECHANISM. PECULIAR PHOTOCHEMICAL PROPERTY OF PYRIMIDO[5,4-G__-]PTERIDINE N__--OXIDE
- Photooxidative Decarboxylation of Indole-3-acetic Acid by Pyrimido[5,4-g]pteridine N-Oxide as a Biomimetic Reaction
- Rearrangement of 5-Cyanouracils into 6-Aminouracils by Reaction with Amines and Hydroxide Ion
- Photochemical Oxidation of 4-Ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (Emorfazone) by Pyrimido[5,4-g]pteridine 5-Oxide. : An Attempt to Apply a Functional Chemical Model for Biological Oxidations to Drug-metabolism Studies
- Pyrimidine Derivatives and Related Compounds. XLVI. Thermal and Photochemical Transformation of 5-Substituted 6-Azido-1,3-dimethyluracils into Fused Pyrimidines such as Isoxazolo [3,4-d] pyrimidines, Pyrazolo [3,4-d]-pyrimidines, and Pyrimido [4,5-d]-[1,2
- Nucleosides. IV. Synthesis and Reactions of 2', 3', 5'-Trichloro-2', 3', 5'-trideoxy-2', 3'-secouridines
- Reactions of 10-Thiaisoalloxazines with Alkyl Amines and Benzyl Alcohol
- A VERSATILE AND CONVENIENT METHOD FOR THE SYNTHESIS OF PYRIMIDO [4,5-b] [1,4] THIAZINES
- Reactions of 6-(N-Methylanilino)-5-(N-phenylimino) pyrimidine-2,4 (3H, 5H)-dione with Benzyl Hydrosulfide and Benzylamine
- Studies of Steroidal α-Amino Acids. I. Synthesis of Two Epimeric 3-Amino-5α-cholestane-3-carboxylic Acids and Their Configuration
- Fused 1,3-Oxazine Derivatives. Synthesis of 2H-1,3-Oxazino [5,6-b]-quinoxaline-2,4 (3H)-diones (1-Oxaalloxazines), 2H-1,3-Oxazino-[6,5-b] quinoline-2,4 (3H)-diones (5-Deaza-1-oxaalloxazines), and 2H-Pyrido [3,2-e]-1,3-oxazine-2,4 (3H)-diones
- Pyrimido-1,4-benzothiazines and -1,4-benzothiazepines. I. Oxidative Coupling and Pummerer Rearrangement of Pyrimido-1,4-benzothiazine and Its Sulfoxide
- Studies on the Smiles Rearrangement. XIV. Novel Reactions of 1,3-Dimethyl-5-nitro-6-chlorouracil with 2-Aminothiophenol
- Studies of Alicyclic α-Amino Acids. III. Synthesis and Biological Evaluation of 3-Amino-1,2,3,4-tetrahydrocarbazole-3-carboxylic Acids
- Photochemical Reactions. XXV. Intramolecular Photooxidation of the Indole Ring by an Aliphatic Nitro Group
- The Ring Contraction of Pyridazinones to Pyrazoles. VII
- Studies on the Smiles Rearrangement. XII. Synthesis and Structural Assignment of Two Isomeric N-Phenyl-2,3-diazaphenothiazinones
- An Unequivocal Synthesis of 1-Methylthio-7-chlorophenazine
- A Novel Photochemical Reaction of Alcohols in the Presence of an Olefin and 2-Aminothiophenol
- The Ring Contraction of Pyridazinones to Pyrazoles. VI.
- The Ring Contraction of Pyridazinones to Pyrazoles. V
- Reduction of the Amidine C=N Bond of 7-Aminofurazano (3,4-d)-pyrimidines with Sodium Borohydride
- Studies of Alicyclic α-Amino Acids and Their Derivatives. V. Decyanization of Alicyclic α-Acetylaminonitriles with Sodium Borohydride
- The Reaction of 5-Phenylazo-6-aminopyrimidines with Lead Tetraacetate. A Convenient Synthesis of 2-Phenyl-7-amino-ν-triazolo [4,5-d]-pyrimidines
- Taxinine Derivatives. The Stereochemistry of Isopropylidene dihydrotaxinolactone, a Novel Autooxidation Product of Isopropylidenedihydrotaxinol
- Studies of Alicyclic α-Amino Acids. IV. Conformational Analysis of Alicyclic α-Amino Acids and Stereochemistry of the Strecker and the Bucherer Reactions
- Studies of Alicyclic α-Amino Acids. II.^ Synthesis and Unequivocal Assignment of Stereochemistry of 1-Amino-trans- and cis-4-hydroxycyclohexane-1-carboxylic Acids
- Studies Related to β-Lactam Antibiotics. IX. Alcoholysis of a 4-Oxa-1-azabicyclo [3.2.0] heptane-3,7-dione
- Nucleosides. II. Direct Synthesis of 5-Substituted 2', 5'-Anhydro-1-β-D-arabinofuranosyluracils from Uridine Derivatives
- Further Studies on the Reaction of 2-Aminothiophenol with Dimethyl Acetylenedicarboxylate
- The Double Smiles Rearrangement
- Steric Effect on the Smiles Rearrangement
- Reactions of Ethyl 3-Methyl-4H-benzo-1,4-thiazine-2-carboxylate with Hydrazine Derivatives
- Taxine. XIV. The Structure of Isopropylidenedihydrotaxinolactone, an Autooxidation Product of Isopropylidenedihydrotaxinol.
- Thermal Reaction of 4-Benzothiazolyldithioazetidinone Novel Formation of Isothiazolone Derivatives
- Facile Thermal Dimerization of a photochemically Isomerized Olefin