Studies on Oxidized Starch Sulfates for Medical Purposes. I. Synthesis of Sulfates of Oxidized Starch and its Derivatives.

スポンサーリンク

概要

• 論文の詳細を見る

• In order to obtain the heparin-like active substances, the sulfates of oxidized starch, obtained by oxidation with nitric acid and its derivatives, were prepared by the reaction with formamide and chlorosulfonic acid. Sulfate of reduced product of oxidized starch, sulfates of oxidized starch amine, sulfates of methyl ester of reduced product of oxidized starch and its reduced product, and demethyl product were also prepared. Reduced product of oxidized starch is found more suitable as a starting material to prepare the heparin-like substances, because reduced product of oxidized starch having no carbonyl group is more stable against degradation during sulfation.

• 公益社団法人日本薬学会の論文
• 1962-03-25

著者

• 富田 栄一

  中外製薬株式会社総合研究所

• 新田 義博

  Research Laboratory, Chugai Pharmaceutical Co., Ltd.

• 行方 正也

  Research Laboratory, Chugai Pharmaceutical Co., Ltd.

• 縄田 喜治

  Central Research Laboratories, Chugai Pharmaceutical Co., Ltd.

• 新田 義博

  Shizuoka College Of Pharmacy

• 富田 栄一

  Research Laboratory, Chugai Pharmaceutical Co., Ltd.

• 縄田 喜治

  Research Laboratory, Chugai Pharmaceutical Co., Ltd.

• 縄田 喜治

  Central Research Laboratories Chugai Pharmaceutical Co. Ltd.

• 行方 正也

  Research Laboratory Chugai Pharmaceutical Co. Ltd.

関連論文

• スルホンアミド類の合成研究(第3報)1,2,4-Benzothiadiazine 1,1-Dioxide類の合成
• Studies on Steroids. II. The Preparation and Properties of 17β-(N-Substituted 2-Amino-4-thiazolyl) androst-4-en-3β, 17α-diol Series and its Hydrogen Succinate.
• Studies on Steroids. I. The Preparation and Properties of 17β-(N-Substituted 2-Amino-4-thiazolyl)-androst-4-en-3-one Series.
• D-Glucarolactone誘導体の研究(第2報) : O-Benzylidene-D-glucarolactoneの構造とアミンの反応
• D-グルカロラクトンとアミンの反応
• Pyrimidine Derivatives. III. The Preparation and Bacteriostatic Activity of Benzamidopyrimidines
• ビリダジン誘導体(第9報) : 2,3-ジアザフェノチアジン誘導体の合成
• Pyridazine Derivatives. X. 10H-Benzo[b]pyridazino[3,4-e][1,4]thiazine and 5H-Benao[b]pyridazino[4,3-e][1,4]thiazine
• Pyridazine Derivatives. VII. Syntheses of 1,2- and 2,3-Diazaphenothiazines
• Pyridazin-derivate. VI. Synthese der Derivate des Imidazo [1,2-b] pyridazins
• Pyridazin-derivate. V. Synthese der Derivate des 6-Phenyl-3 (2H)-pyridazinons.
• 10H-Benz [b] pyridazino [3,4-e] [1,4] thiazin und 5H-Benz [b] pyridazino [4,3-e] [1,4] thiazin
• Pyridazinderivate. III. Synthese der Anilinopyridazine.
• Studies on Analgesics of Aniline Series. III. Preparation and Properties of N, N-Dialkyl 3-(Substituted anilino) butyramide Series
• Studies on Analgesics of Aniline Series. II. Preparation and Properties of N-Alkyl or N, N-Dialkyl 3-(N'-Acyl- or N'-Benzyl-substituted anilino) propionamide Series and N-Alkyl or N, N-Dialkyl 3-(Substituted anilino) propylamine Series
• Studies on Analgesics of Aniline Series. I. Preparation and Properties of β-Alaninamide Series
• Studies on Steroids. III. The Preparation of Steroid-21-yl-glucopyranosiduronamides.
• Studies on Oxidized Starch Sulfates for Medical Purposes. II. Anticoagulant Activity of Sulfates of Oxidized Starch and its Derivatives.
• D-Glucuronolactone Derivatives. VII. Synthesis of Anomeric 1-Deoxy-1-halogeno-2,5-di-O-acyl-D-glucofuranurono-γ-lactones
• Reactions of Nicotinic Acid 1-Oxide with Propionic, Phenylacetic and Benzoic Anhydrides(Organic,Chemical)
• The Mechanism of the Reaction of Nicotinic Acid 1-Oxide with Acetic Anhydride(Organic,Chemical)
• Glucuronosideの加水分解に関する研究(第4報) : Glucofuranosidurono-3,6-lactoneとGlucopyranosiduronic Acidおよびそれらのα-, β-Anomerの酸およびアルカリによる加水分解
• Glucuronosideの加水分解に関する研究(第3報) : β-D-Glucopyranosiduronic Acidのアルカリ分解
• Glucuronosideの加水分解に関する研究(第2報) : β-D-Glucopyranosiduronic AcidのAglyconeが酸加水分解速度に与える影響
• Glucuronosideの加水分解に関する研究(第1報) : β-D-Glucopyranosiduronic Acidの酸触媒反応
• Studies on Oxidized Starch Sulfates for Medical Purposes. I. Synthesis of Sulfates of Oxidized Starch and its Derivatives.
• ピペラジン誘導体の研究(第1報) : 2-Phenylpiperazine誘導体の合成およびその薬理作用
• ピペラジン誘導体の研究(第6報) : 2-Phenylpiperazine誘導体の抗ヒスタミンおよび抗アセチルコリン作用
• ピペラジン誘導体の研究(第2報) : Piperazinoalkylbarbituric Acid誘導体の合成およびその薬理作用
• Studies on Sulfonylurea Derivatives. III. The Infrared Spectra of 1-p-Tolylthio-3-alkylureas and Corresponding Sulfonyl Compounds.
• Studies on Oxidized Starch Sulfates for Medical Purposes. V. Investigation on the Complex of Pepsin with Sulfates of Oxidized Starch and its Reduced Products.
• Studies on Oxidized Starch Sulfates for Medical Purposes. IV. Protective Effect of Sulfates of Oxidized Starch and its Reduced Products on Experimental Peptic Ulceration.
• Studies on Oxidized Starch Sulfates for Medical Purposes. III. Inhibition of the Proteolytic Action of Pepsin by Sulfates of Oxidized Starch and its Reduced Products.
• Derivees des Pyrimidines. II. Synthese des Alcocy-2-Pyrimidyl-4)-N^1-Sulfanilamides
• Pyrimidine Derivatives. I. Synthesis of a New Series of Sulfanilamides having Dialkylamino Groups in the Pyrimidine Nucleus
• Pyridazines. XI. Pyrido[2,3-d]pyridazines. II
• Pyridazine Derivatives. VIII. Pyrido[2,3-d]pyridazines. I.
• The Syntheses of Some Aminomethylindoles
• Synthese der 1,2,3,4-Tetrahydrochinolin-derivate
• Synthesis of Imidazo [4,5-e]-as-triazine (6-Azapurine) Derivatives
• Electronic Structure and Local Anesthetic Activity of 2-Diethylaminoacetanilide Derivatives
• Electronic Structure and Antibacterial Activity of Nitrofuran Derivatives
• Pyridazine Derivatives. IV. The Structures of Aminopyridazines.
• Pyridazine Derivatives. II. Infrared Spectra of O-, N-Mono- and O, N-Dibenzyl Compounds of Maleic Hydrazide.
• Pyridazin-derivate. I. Synthese der Derivate des Oxypyridazins.
• Einwirkungen von Essigsaureanhydrid auf Pyridazin-N-oxyden

もっと見る 閉じる

スポンサーリンク