Studies on Analgesics of Aniline Series. II. Preparation and Properties of N-Alkyl or N, N-Dialkyl 3-(N'-Acyl- or N'-Benzyl-substituted anilino) propionamide Series and N-Alkyl or N, N-Dialkyl 3-(Substituted anilino) propylamine Series
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概要
- 論文の詳細を見る
N-Alkyl or N, N-dialkyl 3-(N'-acyl-, N'-alkyl- or N'-benzylsubstituted anilino)propionamide derivatives were prepared from corresponding N-alkyl or N, N-dialkyl 3-(substituted anilino) propionamides by treating with acid anhydride, alkylhalide, or formaldehyde, formic acid and benzyl chloride, respectively. N, N-Dialkyl 3-(substituted anilino) propylamines were also prepared by condensation of 3-(substituted anilino) propyl chlorides with secondary amines. N, N-Dialkyl 3-(N'-acyl-substituted anilino) propylamines were obtained by treatment of 3-(substituted anilino) propylamines with acid anhydrides. Some of these compounds were found to possess analgetic activities.
- 公益社団法人日本薬学会の論文
- 1965-02-25
著者
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高村 圭一
中外製薬株式会社綜合研究所
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高村 圭一
Research Laboratory, Chugai Pharmaceutical Co., Ltd.
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新田 義博
Research Laboratory, Chugai Pharmaceutical Co., Ltd.
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塩屋 明利
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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源 勝麿
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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山本 忠広
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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吉満 亮人
Research Laboratories, Chugai Pharmaceutical Co., Ltd.
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山本 忠広
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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新田 義博
School Of Pharmacy Hokuriku University
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吉満 亮人
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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塩屋 明利
Research Laboratories Chugai Pharmaceutical Co. Ltd.
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