Metabolism of Drugs. XII. The Effect of β-Diethylaminoethyl Diphenylpropylacetate Hydrochloride (SKF 525-A) on the Metabolism of Ethylhexabital.
スポンサーリンク
概要
- 論文の詳細を見る
It was shown that β-diethylaminoethyl diphenylpropylacetate hydrochloride (SKF 525-A) slowed the rate of biotransformation of ethylhexabital to 3-keto-ethylhexabital and prolonged the duration of hypnosis produced by ethylhexabital.
- 社団法人日本薬学会の論文
- 1957-10-20
著者
-
黒岩 幸雄
Department Of Biochemical Toxicology School Of Pharmaceutical Sciences Showa University
-
黒岩 幸雄
Pharmaceutical Institute Tohoku University School Of Medicine
-
塚元 久雄
Pharmaceutical Institute, Medical Faculty, University of Kyushu
-
高畠 英伍
Pharmaceutical Institute, Medical Faculty, University of Kyushu
-
有吉 敏彦
Pharmaceutical Institute, Medical Faculty, University of Kyushu
-
高畠 英伍
国立公衆衛生院衛生薬学部
-
塚元 久雄
Pharmaceutical Institute. Medical Faculty University Of Kyushu
-
高畠 英伍
Pharmaceutical Institute Medical Faculty University Of Kyushu
関連論文
- Effect of Phenobarbital and 3-Methylcholanthrene on Decrease in pH in Liver induced by 3'-Methyl-4-dimethylaminoazobenzene, of Partial Hepatectomy and Hepatotoxic Agents
- Effect of Citric Acid on 3'-Methyl-4-dimethylaminoazobenzene Induced Decrease in Rat Liver pH
- Reduced Nicotinamide Adenine Dinucleotide-dependent O-Deethylation of p-Nitrophenetole with Rabbit Liver Microsomes. II. Involvement of Cytochrome b_5
- Aliphatic Dehydroxylation of Octopamine in the Rat and Rabbit
- Studies on the Metabolic N-Demethylation. II. Barbiturates Induced Acceleration of N-Methylbarbiturates Metabolism.
- Studies on the Metabolic N-Demethylation. I. The Metabolic Fate of Hexobarbital by Rabbit Liver Slice.
- Metabolism of Drugs. XXI. Isolation and Detection of Hydroxyl Derivatives from the Urine of Rabbits receiving Ethylhexabital (EHB, 5-Cyclohexenyl-5-ethylbarbituric Acid) and Normethylhexabital (Nor-MHB, 5-Cyclohexenyl-5-methylbarbituric Acid).
- Metabolism of Drugs. XII. The Effect of β-Diethylaminoethyl Diphenylpropylacetate Hydrochloride (SKF 525-A) on the Metabolism of Ethylhexabital.
- 2-或いは4-ピリジンアルデヒドの簡易合成法
- 薬学研究奨励財団
- Enzyme Immunoassay for Cinobufagin
- Biochemical Studies on the Drug Metabolism. IV. Adaptive Increases in Cyclobarbital-Metabolizing Enzyme Induced by Barbiturate Derivatives
- Synthesisof p-Nitrophenyl β-D-Glucopyranosiduronic Acid and Its Utilization as a Substrate for the Assay of β-Glucuronidase Activity
- Differential Induction of Hepatic and Renal Microsomal Cytochrome P450 by N-Phenylalkylimidazoles in Rats
- 食品の安全性を再考する
- Metabolism of Drugs. XIV. Metabolic Fate of p-Aminosalicylic Acid in the Rabbit. (2)
- Isolation of Glucuronide of p-Aminosalicylic Acid
- 銅化合物投与ラット臓器中の銅の分布と必須金属への影響
- 高速液体クロマトグラフィーによる鶏肉中のスルファモノメトキシン,ジニトルミド,工トパベート,スルファジメトキシン,スルファキノキサリンの同時定量
- WHOと環境保健国際活動
- 模倣と独創
- 畜水産用薬物の現況と問題点
- 有害化学物質 : 毒性と環境(化学教育における環境問題のとらえ方)
- ラット肝ミクロソームモノオキシゲナーゼに対する併用化学物質の影響(第2報)ポリ塩化ビフェニルとカドミウム
- ラット肝ミクロソームモノオキシゲナーゼに対する併用化学物質の影響(第1報)ポリ塩化ビフェニルとジエチルヘキシルフタレート
- 薬物代謝研究の今昔
- 環境汚染物質と毒性無機物質
- まずは土台を築くこと(衛生薬学領域における教育はいかにあるべきか)
- FIP総会に出席して
- International Conference on In Vivo Aspects of Biotransformation and Toxicity of Industrial and Environ-mental Xenobiotics
- Pharmacobiodynamics
- 座長のまとめ(107〜109) (第二回毒作用研究会記事)
- 環境ならびに生体試料中の総フタール酸エステル類のガスクロマトグラフィーによる定量法
- 石油ワックスおよび合成ワックス中のベンゾ[a]ピレンの定量
- 食品中の多核芳香族炭化水素の定量-5-果実中の3,4-ベンズピレン(ノ-ト)
- Metabolism of Drugs. XXII. The Metabolic Fate of Thiamylal. (1)
- 薬品の生体内変化に関する研究(第5報)Ethylhexabital代謝産物の排泄速度
- エチルヘキサビタールの生体内変化に関する研究-3-
- Metabolism of Drugs. XI. The Relationship between Hypnotic Activity and Metabolism of Ethylhexabital. (2). The Effect of Sex Hormones.
- Metabolism of Drugs. X. The Relationship between Hypnotic Activity and Metabolism of Ethylhexabital. (1) The Influence of Species, Sex, and Age on the Activity of Liver to Metabolize Ethylhexabital and the Isolation of an in vitro Metabolite.
- Ethylhexabitalのラッて肝臓切片による試験管内変化
- 環境試料, 特に底質中メチル水銀の定量法
- ガスクロマトグラフィーによる鶏肉および鶏卵中クロピドールの分析
- 固体による無機水銀(2)の光増感メチル化反応
- Studies on The Metabolic N-Demethylation. VII. Effect of p-Hydroxyphenobarbital on the Oxidative Demethylation in Rat Liver
- Studies on the Metabolic N-Demethylation. VI. Effect of Morphine and Nalorphine on the Oxidative Demethylation in Vitro in the Liver from Intact and Adrenalectomized Rats
- Studies on the Metabolic N-Demethylation. V. Effect of Phenobarbital on the Oxidative Demethylation in Vitro in the Liver of Adrenalectomized Rats
- 尿中よりモルヒネおよびN-アリルノルモルヒネ(ナロルフィン)の分離定量
- Studies on the Metabolic N-Demethylation. IV. Effects of Phenobarbital and Morphine on the Oxidative Demethylation in Rat Liver
- Studies on the Metabolic N-Demethylation. III. Acceleration of Drug Metabolizing Enzyme in Rat Liver.
- モルヒネおよびフェノバルビタール前処置ラット血漿中のコルチコステロン量および肝における脱メチル活性
- Regio-Related Differential Induction of Hepatic Microsomal Heme Oxygenase and Cytochrome P450 by Substituted Imidazole and Pyridine Compounds in Rats
- Metabolism of Drugs. XV. Isolation and Paper Chromatography of Urinary Glucuronide of Salicylic Acid in the Rabbit.
- Effect of Tolbutamide on the Metabolism of Parathion
- 医薬品の生体内変化に関する研究(第8報)メチルヘキサビタールの生体内変化 その4 メチルヘキサビタール代謝物及び関連化合物の紫外, 赤外線吸収スペクトルについて
- Biochemical Studies on the Drug Metabolism. I. Some Factors Affecting on the Metabolism of Cyclobarbital.
- 薬品の生体内変化に関する研究(第1報) : Ethylhexabital(5-Cyclohexenyl-5-ethylbarbituric Acid)の生体内変化
- Metabolism of Drugs. XVIII. : The Metabolic Fate of Methylhexabital (5-Cyclohexenyl-3,5-dimethylbarbituric Acid). (8). : The Quantitative Determination of Main Biotransformation Products of Methylhexabital in the Urine of Rabbits by Ultraviolet Spectropho
- Metabolism of Drugs. XVII. Metabolic Fate of Methylhexabital (5-Cyclohexenyl-3,5-dimethylbarbituric Acid). (7). Separation and Identification of Biotransformation Products of Methylhexabital in the Urine of Rabbits by Paper Chromatography.
- 医薬品の生体内変化に関する研究(第7報)メチルヘキサビタールの生体内変化 その3 メチルヘキサビタール代謝物について
- Metabolism of Drugs. XIX. Metabolic Fate of p-Aminosalicylic Acid in the Rabbit. (3).
- 薬品の生体内変化に関する研究(第4報)p-Aminosalicylic Acidの家兎における生体内変化 その1
- Enzymatic Oxidation of Methylhexabital
- Metabolism of Drugs. XX. Metabolic Fate of Methylhexabital (5-Cyclohexenyl-3,5-dimethylbarbituric Acid). (9). Interconversion of 3-Keto-MHB (5-(3-Oxo-1-cyclohexenyl)-3,5-dimethylbarbituric Acid) and 3-OH-MHB (5-(3-Hydroxy-1-cyclohexenyl)-3,5-dimethylbarbi
- Detection of Hydroxyl Derivatives from the Urine of Men administered Ethylhexabital and Methylhexabital by Buffered Paper Chromatography.
- 医薬品の生体内変化に関する研究(第6報)メチルヘキサビタールの生体内変化 その2 メチルヘキサビタール及びノルメチルヘキサビタールのクロム酸酸化について
- 薬品の生体内変化に関する研究(第2報)Ethylhexabital(5-Cyclo-5-ethylbarbituric Acid)の生体内変化
- Metabolism of Benzydamine Hydrochloride : Species Differences and the Identification of Unconjugated Metabolites in Rabbit Urine
- 食品中の多核芳香族炭化水素の定量-4-魚介類中の3,4-ベンズピレン
- 対馬佐須地区住民の尿中カドミウム排泄量(第2報)中学生の調査結果
- メチルアルシンスルフィドの生体内分布, 排泄および肝臓成分と薬物代謝酵素系に対する影響
- 薬品の生体内変化に関する研究(第3報)Methylexabital(5-Cyclohexenyl-3,5-dimethyl-barbituric Acid)の生体内変化 その1
- Effect of Diphenylhydantoin on the Drug Metabolism and the Fatty Acid Composition of Phospholipids in Hepatic Microsomes
- Effects of Phenobarbital, Ethanol and Ethionine on the Content and Fatty Acid Composition of Hepatic Microsomal Phospholipids
- Biochemical Studies on the Drug Metabolism. II. Inductive Effect of Malonic Acid Derivatives on Cyclobarbital-Metabolizing Enzyme in Rat Liver