Metabolism of Drugs. XXI. Isolation and Detection of Hydroxyl Derivatives from the Urine of Rabbits receiving Ethylhexabital (EHB, 5-Cyclohexenyl-5-ethylbarbituric Acid) and Normethylhexabital (Nor-MHB, 5-Cyclohexenyl-5-methylbarbituric Acid).
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概要
- 論文の詳細を見る
3-OH-EHB was isolated from the urine of rabbits receiving EHB besides 3-keto-EHB and identified with the reduction product of 3-keto-EHB. After the administration of nor-MHB to rabbits, 3-OH-nor-MHB was also detected from the urine, using buffered paper chromatography. Both 3-OH-EHB and 3-OH-nor-MHB have no hypnotic action.
- 社団法人日本薬学会の論文
- 1959-09-20
著者
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黒岩 幸雄
Department Of Biochemical Toxicology School Of Pharmaceutical Sciences Showa University
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黒岩 幸雄
Pharmaceutical Institute Tohoku University School Of Medicine
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塚元 久雄
Pharmaceutical Institute, Medical Faculty, University of Kyushu
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塚元 久雄
Pharmaceutical Institute. Medical Faculty University Of Kyushu
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