MONOCLONAL ANTIBODIES AGAINST KERATINS BIND TO INTERCALATED DUCT AND DUCTAL BASAL CELLS OF NORMAL SALIVARY GLANDS IN PARAFFIN SECTIONS
スポンサーリンク
概要
- 論文の詳細を見る
Intercalated duct cells and ductal basal cells in the salivary glands were suggested to be probable progenitor cells of salivary gland tumors. Different monoclonal anti-keratin antibodies (KL1, PKK1, PKK2, PKK3, RGE53, K4.62, K8.12, K8.13, K8.60, RPN1160, RPN1161, RPN1162, RPN1163, RPN1164, RPN1165, RPN1166) and polyclonal anti-keratin antiserum (TK) were tested on paraffin sections of Carnoy's- and formalin-fixed normal salivary gland tissues (parotid and submandibular glands). Monoclonal keratin antibodies could detect nos. 1, 5, 6, 7, 8, 10, 11, 13, 16, 17, 18, and 19 keratins. Intercalated duct cells of normal salivary glands displayed positive staining with monoclonal antibodies KL1, K4.62, K8.12, K8.13, K8.60, RPN1160, and RPN1164. Ductal basal cells revealed positive staining with PKK1 (nos. 19 or 18, 8) (Carnoy's fixed section), and K8.12 (nos. 16, 13), K4.62 (no. 19), RPN1165 (no. 19) keratins, which bind to nos. 19, 18, 16, 13, 8. Intercalated duct cells contained wide spectrum keratins. Keratin stainings (nos. 19 or 16, 13) of ductal basal cells in formalin fixed sections suggested nos. 19, 16, 13 proteins to be some marker for progenitor cells of salivary gland tumors.
- 日本組織細胞化学会の論文
著者
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TAKAI Yoshiaki
Department of Electronics Engineering, Nagoya University
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YAMADA Kazuo
Department of Biochemistry, Faculty of Medicine, Shimane University
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MORI Masahiko
Department of Oral Pathology, Osaka Dental University
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Mori M
Department Of Oral-maxillofacial Surgery Asahi University School Of Dentistry:medicaraise Corporatio
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Mori Masahiko
Department Of Oral Pathology Osaka Dental University
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Yamada K
Department Of Anatomy School Of Health Sciences Fujita Health University
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Yamada Keiki
Dept. Anat. Sch. Hygiene Fujita-gakuen Univ.
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Yamada K
Department Of Oral And Maxillofacial Surgery Asahi University School Of Dentistry:department Of Oral
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Takai Y
Department Of Oral-maxillofacial Surgery Asahi University School Of Dentistry
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Takai Yoshiaki
Department Of Oral And Maxillofacial Surgery Asahi University School Of Dentistry
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Mori M
Department Of Oral Surgery Asahi University School Of Dentistry
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SHINOHARA HIROYUKI
Department of Oral Surgery, Asahi University, School of Dentistry
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ORITO TADASHI
Department of Oral Surgery, Asahi University School of Dentistory
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TSUKITANI KOJI
Department of Dentistry, Kyoto Prefectural University of Medicine
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Shinohara Hiroyuki
Department Of Oral Surgery Asahi University School Of Dentistry
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Shinohara Haruo
Department Of Oral Surgery Asahi University School Of Dentistry
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Orito Tadashi
Department Of Oral Surgery Asahi University School Of Dentistory
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Tsukitani Koji
Department Of Dentistry Kyoto Prefectural University Of Medicine
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Muto Masahiro
Department Of Oral Pathology Osaka Dental University
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Takai Yoshiaki
Depertment Of Oral Surgery Gifu College Of Dentistry
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Mori Masahiko
Department Of Oral And Maxillofacial Surgery Asahi University School Of Dentistry
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Mori Masahiko
Department Of Applied Chemistry Faculy Of Engineering And High Technology Research Center Kansai Uni
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Yamada Kazuo
Department Of Biochemistry Faculty Of Medicine Shimane University
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Yamada Kazuo
Department Of Architecture Faculty Of Engineering Aichi Institute Of Technoligy
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Shinohara Hiroyuki
Department Of Applied Chemistry Graduate School Of Engineering Osaka Prefecture University
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Takai Yoshiaki
Department of Electrical Engineering and Computer Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
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Yamada Kazuo
Department of Applied Molecular Chemistry, College of Industrial Technology, Nihon University
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