トリフェニル鉛イソカルボン酸エステルの抗菌性について

概要

論文の詳細を見る
Antimicrobial actions of triphenyl lead iso-carboxylates on microbes were studied in relation to the type on their chemical structures.Triphenyl lead iso-carboxylates were used in the forms of iso-butyrate, iso-valerate, trimethylacetate, methylethylacetate, iso-caprotate, diethylacetate, 3-methylpentanate, 2-methylpentanate, 2-ethylpentanate, 2-ethylhexanate, 2-methylhexanate, 3-methylheptabate, 3-ethylheptanate and 2.4-dimethylpentanate.The microbes used in the tests were Candida albicans, Aspergillus niger, Rhizopus nigricas, Trichorderma viride, Fusarium moriniforme and Bacillus subtilis.As the results, it was found that the antimicrobial activities of iso-compounds were stronger than those of n-compounds.The activies of teriary and secondary branched-chain compounds were higher than those of straight compounds.The activities of branched-chain compounds were affected by the positions of the branches, and the α-position was always more effective than the β-position.α-Methyl and α-ethyl derivatives of tripheny lead carboxyrates showed strong growth-inhibitory actons on the microbes and the former is always more powerful than the latter.
1969-10-25