トリフェニル鉛化合物の抗菌性について

概要

論文の詳細を見る
Triphenyl lead carboxylic acid esters were synthesized and tested for their antimicrobial actions on microbes. Triphenyl lead carboxylic acid esters synthesized were acetic, propionic, butyric, valeric, caproic, enanthic, caprylic, capric, lauric, fumaric and maleic esters.Candida albicans, Aspergillus niger, Rhizopus nigricans, Trichoderma viride, Trichophytom mentagrophytes, Fusarium moriniforme and Bacillus subtilis were used for antimicrobial tests.As the results of antimicrobial tests of the triphenyl lead n-carboxylic acid esters, it was found that the activities of the esters were generally increased with the decrease of carbon atom number of the acyl group. Activity of maleic ester (cis type) was higher than fumaric ester (trans type).The activities of triphenyl lead carboxylic acid esters were remarkably increased with the decrease of pH. Results indicated that the antimicrobial action of employed compounds was produced by a prolongation of the lag phase.
公益社団法人日本生物工学会の論文
1967-08-25