芳香族脂肪酸の化学構造と抗菌性 (第4報)

概要

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α-phenyl acetic acid, β-phenyl-propionic acin, γ-phenyl-n-butyric acid, δ-phenyl-n-valeric acid, ε-phenyl-n-caproic acid, ζ-phenyl-enanthic acid, β-benzoyl-propionic acid and α・β-dichloro-β-phenyl-propionic acid were prepared and their antimicrobial activity against the yeasts (Kyokai No. 6,Sac. formosensis), molds (Asp. awamori and Rh. japonicus), and bacteria (Bac. subtilis and Lactobacillus delbrucki)were examined.The results are summarized as follows : -1) The antimicrobial action of the aromatic saturated fatty acids mentioned above increases with the number of carbon of the side chain.2) The power of ζ-phenyl-enanthic acid against the microorganisms was stronger than that of the other acids.3) The antimicrobial effectiveness of ζ-phenyl-enanthic acid was proportional to the concentration of its nondissociated molecules. 4) The antimicrobial action of ζ-phenyl-enanthic acid belongs to the Type IV, a fact which is recognized by the descent of growth curve.
公益社団法人日本生物工学会の論文
1960-05-15