Structural Studies and Antifungal Activity of Unique Polyene Amides, Clathrynamide A and Three New Derivatives, from a Marine Sponge, Psammoclemma Sp.(Organic Chemistry)
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概要
- 論文の詳細を見る
Known polyene amide, clathrynamide A, and three novel related metabolites, debromoclathrynamide A, (4E, 6E) -debromoclathrynamide A and (6E) -clathrynamide A, were isolated from an Okinawan marine sponge, Psammoclemma sp. The absolute stereochemistry of clathrynamide A was determined to be 3R, 12R by the modified Mosher method. The structures of the three new compounds were elucidated by spectroscopic analyses as debromo derivatives and geometrical isomers. Their antifungal activities were also evaluated with a phytopathogenic fungus, indicating that both the bromine atom and double-bond geometry affected the activity.
- 社団法人日本農芸化学会の論文
- 2003-07-23
著者
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Suzuki Yoshihiro
Graduate School Of Bioagricultural Sciences Nagoya University
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Sakagami Y
Nagoya Univ. Nagoya Jpn
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Sakagami Youji
Graduate School Of Bioagricultural Sciences Nagoya Univ.
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Sakagami Youji
Graduate School Of Bio-agricultural Sciences Nagoya University
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Okada Masahiro
Graduate School Of Biological Sciences Nara Inst. Of Sci. And Technol.
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OJIKA Makoto
Graduate School of Bioagricultural Sciences, Nagoya University
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ITOU Yu
Graduate School of Bioagricultural Sciences, Nagoya University
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Itou Yu
Graduate School Of Bioagricultural Sciences Nagoya University
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Ojika M
Graduate School Of Bioagricultural Sciences Nagoya University
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Ojika Makoto
Graduate School Of Bioagricultural Sciences Nagoya Univ.
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Suzuki Yoshihiro
Graduate School of Bioagricultural Sciences, Nagoya University
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Yu Itou
Graduate School of Bioagricultural Sciences, Nagoya University
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