Cytotoxic substances from two species of Japanese sea hares: chemistry and bioactivity
スポンサーリンク
概要
- 論文の詳細を見る
From the sea hares belonging to two genera, Aplysia and Dolabella, a variety of new cytotoxic substances were isolated as minute constituents: their chemical structures were determined and their cytotoxicity was evaluated. Regarding the highly cytotoxic substances, further chemical and biological studies were performed that included their asymmetric chemical synthesis and elucidation of biological characteristics such as antitumor activity.(Communicated by Satoshi OMURA, M.J.A.)
- 日本学士院の論文
著者
-
Kigoshi Hideo
Graduate School Of Pure And Applied Sciences University Of Tsukuba
-
Kigoshi H
Department Of Chemistry Faculty Of Science Nagoya University
-
OJIKA Makoto
Graduate School of Bioagricultural Sciences, Nagoya University
-
YAMADA Kiyoyuki
Professor Emeritus, Nagoya University
-
SUENAGA Kiyotake
Faculty of Science and Technology, Keio University
-
Ojika Makoto
Graduate School Of Bioagricultural Sciences Nagoya Univ.
-
KIGOSHI Hideo
Graduated School of Pure and Applied Sciences, University of Tsukuba
関連論文
- Stereoselective Incorporation of Isoleucine into Cypridina Luciferin in Cypridina hilgendorfii (Vargula hilgendorfii)
- Towards Structural Determination of the ComX Pheromone : Synthetic Studies on Peptides Containing Geranyltryptophan
- P-137 Cyclohaliclonamines and Phormidinines, Novel 3-Alkylpyridinium and 2-Alkylpyridine Alkaloids from Marine Organisms
- Spongiacysteine, a Novel Cysteine Derivative from Marine Sponge Spongia sp
- Construction of a Bacterial Artificial Chromosome Library for a Myxobacterium of the Genus Cystobacter and Characterization of an Antibiotic Biosynthetic Gene Cluster
- Biotransformation of Cystothiazole A, a Myxobacterial Antibiotic, into Novel Derivatives by the Mother Producer, Cystobacter fuscus
- Biosynthetic Studies on a Myxobacterial Antibiotic, Cystothaiazole A: Biosynthetic Precursors of the Carbon Skeleton
- New Cyclic Depsipeptide Antibiotics, Clavariopsins A and B, Produced by an Aquatic Hyphomycetes, Clavariopsis aquatica : 2. Structure Analysis
- New Cyclic Depsipeptide Antibiotics, Clavariopsins A and B, Produced by an Aquatic Hyphomycetes, Clavariopsis aquatica : 1. Taxonomy, Fermentation, Isolation, and Biological Properties
- Cystothiazoles A and B, New Bithiazole-type Antibiotics from the Myxobacterium Cystobacter fuscus
- P-446 Crystal Structure of Actin Complex with Aplyronine A, an Antitumor Substance of Marine Origin
- Structural Studies and Antifungal Activity of Unique Polyene Amides, Clathrynamide A and Three New Derivatives, from a Marine Sponge, Psammoclemma Sp.(Organic Chemistry)
- Efficient Conversion of Tomatidine into Neuritogenic Pregnane Derivative
- Synthesis of the Aglycon of Aurisides A and B, Cytotoxic Macrolide Glycosides of Marine Origin
- Cytotoxic substances from two species of Japanese sea hares: chemistry and bioactivity
- Isolation of Tribromoacetamide from an Okinawan Alga and Biological Activities of Its Analogs
- Determination of the Luciferin Contents in Luminous and Non-Luminous Beetles
- Miuraenamides A and B, Novel Antimicrobial Cyclic Depsipeptides from a New Slightly Halophilic Myxobacterium : Taxonomy, Production, and Biological Properties
- Three New Cytotoxic Acylspermidines from the Soft Coral, Sinularia sp.(Organic Chemistry)
- Prostaglandins from a Zoanthid : Paclitaxel-Like Neurite-Degenerating and Microtubule-Stabilizating Activities
- 16(I-2) Novel Saponins from the Okinawan Starfish Linckia laevigata : Structure Determination, Neuritogenic Activity, and Mechanism of Action
- Zooxanthellactone, a Novel γ-Lactone-type Oxylipine from Dinoflagellates of Symbiodinium sp : Structure, Distribution, and Biological Activity
- Stereostructure and Bioactivities of Jolkinolide D
- Linckosides M-Q : neuritogenic steroid glycosides from the Okinawan starfish Linckia laevigata
- P-207 Linckosides, novel neuritogenic steroid glycosides from the Okinawan starfish Linckia laevigata
- Biosynthesis of 2'-O-Methylmyxalamide D in the Myxobacterium Cystobacter fuscus : a Polyketide Synthase-Nonribosomal Peptide Synthetase System for the Myxalamide D Skeleton and a Methyltransferase for the Final O-Methylation
- Novel Relationship between the Antifungal Activity and Cytotoxicity of Marine-Derived Metabolite Xestoquinone and Its Family
- Differentiation in a Rat PC12 Cell Line Induced by Ostruthin and (-)-Bornyl Ferulate, Constitutents of a Chinese Herbal Medicine
- Synthetic Studies on Mycalolide B : Synthesis of the C7-C35 Fragment
- P-402 Synthetic Studies on Mycalolide B, an Actin-depolymerizing Marine Macrolide
- Enzymatic and Genetic Characterization of Firefly Luciferase and Drosophila CG6178 as a Fatty Acyl-CoA Synthetase
- Zooxanthellamide B, a Novel Large Polyhydroxy Metabolite from a Marine Dinoflagellate of Symbiodinium sp
- P-306 Study of the Interaction between Actin and Antitumor Substance Aplyronine A with a Novel Fluorescent Photoaffinity Probe
- Isolation of Two 13-epi-Neoverrucosane-Type Diterpenoids from a Marine Sponge Axinyssa tethyoides
- Biselides A and B, Novel Macrolides from the Okinawan Ascidian Didemnidae sp
- Determination of the Luciferin Contents in Luminous and Non-Luminous Beetles
- Aplysiallene, a New Bromoallene as an Na, K-ATPase Inhibitor from the Sea Hare, Aplysia kurodai
- New Neuritogenic Steroidal Saponin from Ophiopogon japonicus (Thunb.) Ker-Gawl
- New Neuritogenic Steroidal Saponin from Ophiopogon japonicus (Thunb.) Ker-Gawl
- Novel Cytotoxic Polyoxygenated Steroids from an Okinawan Sponge Dysidea sp.
- Termitomycesphins G and H, Additional Cerebrosides from the Edible Chinese Mushroom Termitomyces albuminosus
- Novel Cerebroside, Termitomycesphin I, from the Mushroom, Termitomyces titanicus
- Novel Cerebroside, Termitomycesphin I, from the Mushroom, Termitomyces titanicus