Effect of Dissolved Oxygen and pH on Moranoline (1-Deoxynojirimycin) Fermentation by Streptomyces lavendulae
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概要
- 論文の詳細を見る
The intent of this work was to investigate the effects of control of DO and pH on moranoline (1-deoxynojirimycin) production by Streptomyces lavendulae for large-scale moranoline fermentation. The conclusious reached are as follows : (i) It is most important to maintain DO at 20% saturation from the stage of fermentation when the rate of DO consumption is high. (ii) When the DO is maintain between 20 and 85% saturation, it is important to maintain pH at less than 7. When the fermentation was carried out so as to maintain the DO at 20% saturation in a 30 l fermentor, 10.2-10.5 g/・l^<-1> of moranoline was produced.
- 社団法人日本生物工学会の論文
- 1995-04-25
著者
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Kojima M
Department Of Bioresource Chemistry Obihiro University Of Agriculture And Veterinary Medicine
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EZURE Yohji
Discovery Research Laboratory III Nippon Shinyaku Co., Ltd.
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MARUO Shigeaki
Discovery Research Laboratory III Nippon Shinyaku Co., Ltd.
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Maruo Shigeaki
Chemistry Laboratories, Nippon Shinyaku Co., Ltd.
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Kyotani Yohsuke
Chemistry Laboratories, Nippon Shinyaku Co., Ltd.
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Kojima Masahiko
Chemistry Laboratories, Nippon Shinyaku Co., Ltd.
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Ezure Yohji
Chemistry Laboratories, Nippon Shinyaku Co., Ltd.
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Tachikake Noriyuki
Chemistry Laboratories, Nippon Shinyaku Co., Ltd.
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KYOTANI Yohsuke
Discovery Research Lab. III, Nippon Shinyaku Co., Ltd.
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Kojima M
Department Of Agricultural And Life Sciences Obihiro University Of Agriculture And Veterinary Medici
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Ezure Y
Discovery Research Laboratory Iii Nippon Shinyaku Co. Ltd.
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Maruo Shigeaki
Discovery Research Laboratory Iii Nippon Shinyaku Co. Ltd.
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KONNO KIYOTAKA
Chemistry Lavoratories, Nippon Shinyaku Co. Ltd.
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YAMAMOTO MASASHI
Chemistry Laboratories, Nippon Shinyaku Co. Ltd.
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Kyotani Yohsuke
Discovery Research Lab. Iii Nippon Shinyaku Co. Ltd.
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Konno Kiyotaka
Chemistry Lavoratories Nippon Shinyaku Co. Ltd.
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Tachikake Noriyuki
Discovery Research Laboratory Iii Nippon Shinyaku Co. Ltd.
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Yamamoto M
Tokyo Medical And Dental Univ. Tokyo Jpn
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Komai Michio
Nof Corporation
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Yamamoto Masashi
Chemical Resources Laboratory Tokyo Institute Of Technology
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