Molecular Cloning of a Gene Responsible for the Biosynthesis of the Lipopeptide Antibiotics Iturin and Surfactin
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概要
- 論文の詳細を見る
A gene responsible for the production of iturin and surfactin was cloned and analyzed in the original wild strain Bacillus subtilis RB14,a coproducer of surfactin and iturin, as well as in B. subtilis MI113,a derivative of strain B. subtilis 168. The cloned gene lpa (lipopeptide antibiotic production) permitted only surfactin production in strain MI113,but when it was destroyed in RB14,the defective strain simultaneously lost the ability to produce both surfactin and iturin. The ability was restored by the introduction of the intact lpa gene into the strain.
- 公益社団法人日本生物工学会の論文
- 1992-11-25
著者
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正田 誠
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Ano T
Tokyo Inst. Technol. Yokohama Jpn
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Ano Takashi
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Shoda Makoto
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Shoda Makoto
Research Laboratory Of Resources Utiluzation Tokyo Institute Of Technology
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HIRAOKA HIDEJI
Research Laboratory of Resources Utilization, Tokyo Institute of Technolgy
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Hiraoka Hideji
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Shoda Makoto
Research Lab. Resources Utilization Tokyo Institute Of Technology
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