lpa-14, a Gene, Involved in the Production of Lipopeptide Antibiotics, Regulates the Production of a Siderophore, 2, 3-Dihydroxybenzoylglycine, in Bacillus subtilis RB14
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概要
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A gene designated lpa-14, which was cloned from Bacillus subtilis RB14 and was associated with the production of lipopeptide antibiotics, was found to be involved in the production of an iron-chelating siderophore, 2, 3-dihydroxybenzoylglycine(2, 3-DHBG). Although strain RΔ1, an lpa-14 defective mutant of RB14, showed no growth in iron-deficient medium in contrast to the marked growth of RB14 in the same medium, the addition of chemically synthesized 2, 3-DHBG at approximately 100 ppm caused the growth of RΔ1 to be resumed.
- 社団法人日本生物工学会の論文
- 1998-12-25
著者
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Liao Zha
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Ano Takashi
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Shoda Makoto
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Huang Chieh-chen
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Hirai Mitsuyo
Research Laboratory Of Resources Utilization Tokyo Institute Of Technology
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Shoda Makoto
Research Lab. Resources Utilization Tokyo Institute Of Technology
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