Improvement of Hospital Preparation for Patient Oriented Service : Tablet of Bitter Tasting-Stomachic Powder
スポンサーリンク
概要
- 論文の詳細を見る
A bitter stomachic powder, named NGD powder, has been prepared at our hospital. However, a questionnaire survey conducted by the Japanese Society of Hospitai Pharmacists reveals that elderly patients complain of difficulty in taking this formula because of its bitter taste and dustiness. Therefore, we attempted to reformulatier this NGD powder in tablet form and to study the pharmaceutical properties of the subsequently produced NGD tablets. Microcrystalline cellulose (MCC) was added in amounts of 20%, 30% and 40% to its amount of NGD powder, and compressed using a compression force of O.5, 1.0, 1.5 or 2.0 ton/cm^2 These tablets were then examined for their crushing strength, friability. disintegration time, neutralizing capacity and amylosaccharifying activity. Moment analysis was carried out especially for the neutralizing capacity of the tablets. Optimum regression equations were obtained using multiple regression analysis for each of the characteristics. The results suggest that the optimum amount of MCC and compression force are 30% and 1.0 ton/cm^2, respectively.
- 日本医療薬学会の論文
- 1998-08-10
著者
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MATSUMOTO Yoshiaki
Department of Clinical Pharmacology and Toxicology, Showa College of Pharmaceutical Sciences
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ENDO Hisashi
Department of Medical Oncology, Comprehensive Cancer Center, Saitama Medical University
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Endo H
Department Of Pharmacy Yokohama City University Hospital
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Endo Hisashi
Department Of Medical Oncology Comprehensive Cancer Center Saitama Medical University
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Matsumoto Mitsuo
Department of Pharmaceutics, Showa Pharmaceutical University
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SHIROTAKE Shoichi
Department of Pharmacy, Yokohama City University Hospital
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Matsumoto Yoshiaki
Department Of Clinical Pharmacology And Toxicology Showa Pharmaceutical University
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Shirotake Shoichi
Department Of Pharmaceutics And Biopharmaceutics Showa Pharmaceutical University
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Matsumoto Mitsuo
Department Of Pharmaceutics Showa Pharmaceutical University
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Murata Masahiro
Department Of Pharmacy Services Tama Nagayama Hospital Nippon Medical School
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Iwata Masanori
Department of Obstetrics and Gynecology, St. Marianna University School of Medicine Tohyoko Hospital
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ICHISAWA MASAYUKI
Department of Pharmacy, Yokohama City University Hospital
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Ichisawa Masayuki
Department Of Pharmacy Yokohama City University Hospital
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Iwata Masanori
Department Of Obstetrics And Gynecology St. Marianna University School Of Medicine Tohyoko Hospitall
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Endo H
Department Of Drug Metabolism Research Center Taisho Pharmacetutical Co. Ltd.
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Matsumoto Mitsuo
Department Of Pharmaceutics And Biopharmaceutics Showa Pharmaceutical University
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Matsumoto Yoshiaki
Department Of Clinical Pharmacokinetics College Of Pharmacy Nihon University
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Matsumoto Yoshiaki
Department Of Clinical Pharmacology And Toxicology Showa College Of Pharmaceutical Sciences
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Shiraishi Shuji
Department Of Pharmaceutics And Biopharmaceutics Showa Pharmaceutical University
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Matsumoto Mitsuo
Department Of Ophthalmology Hirosaki University School Of Medicine
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ENDO HISASHI
Department of Internal Medicine, National Shikoku Cancer Center
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Matsumoto Mitsuo
Department of Hydrocarbon Chemistry, Faculty of Engineering, Kyoto University
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