Particulate Matter Analyses after Dissolution of Powder Antibiotic Injections Used in the Pediatric Ward
スポンサーリンク
概要
- 論文の詳細を見る
Final filters have not been always used for injections in the pediatric ward of our hospital. Since thore has been no report on the particulate matters of five dissolved antibiotics in vial, we measured those amounts using a particle counter. The amounts of particulate matters in the solutions of cefpirome sulfate, flomoxef sodium and panipenem/betamipron were below the limits defined by the Japanese Pharmacopoeial Forum(1996) or United States Pharmacopoeia (USP XXIII). However, particles above 10μm in imipenem/cilastatin sodium and vancomycin hydrochloride immediately after dissolution were about 70% of the limit. Scanning electron micrographs of the filter membrane surface showed the existence of insoluble particulate contaminants in those injections. Final filters are recommended for these antibiotic injections to be used safely in pediatric patients.
- 日本医療薬学会の論文
- 1998-08-10
著者
-
Sendo Toshiaki
Dep. Of Hospital Pharmacy Okayama Univ. Medical School Jpn
-
Sendo Toshiaki
岡山大学 医歯薬学総合研究科薬理学
-
Sendo Toshiaki
Department Of Hospital Pharmacy Okayama University Medical And Dental School
-
Sendoh Toshiaki
九州大学 薬
-
Sendo T
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
-
Sendo Toshiaki
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
-
KATAOKA Yasufumi
Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences, Fukuoka U
-
Ryozo Oishi
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
-
FUTAGAMI Koujiro
Department of Hospital Pharmacy, Okayama University Medical School
-
HIRAKAWA MASAAKI
Department of Hospital Pharmacy, Faculty of Medicine, Kyushu University
-
IMAFUKU SAORI
Department of Hospital Pharmacy, Faculty of Medicine, Kyushu University
-
Imafuku Saori
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University:(present)omuta National Hospit
-
Kataoka Y
Department Of Pharmaceutical Care And Health Sciences Faculty Of Pharmaceutical Sciences Fukuoka Uni
-
Kataoka Yasufumi
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
-
Kataoka Yasufumi
Department Of Pharmaceutical Care And Health Sciences Faculty Of Pharmaceutical Sciences Fukuoka Uni
-
Kataoka Yasufumi
Faculty Of Pharmaceutical Sciences Fukuoka University
-
Futagami Koujiro
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
-
Futagami Koujiro
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University:(present)department Of Hospita
-
Hirakawa Masaaki
Department Of Applied Chemistry Faculty Of Engineering Seikei University
-
Hirakawa Masaaki
Department Of Hospital Pharmacy Faculty Of Medicine Kyushu University
-
Kataoka Yasufumi
Department Of Pharmaceutical Care And Health Sciences Faculty Of Pharmaceutical Sciences Fukuoka Uni
-
Sendo Toshiaki
Department of Clinical Pharmacy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
関連論文
- Nicotinic Acetylcholine α4β2 Receptor Regulates the Motivational Effect of Intracranial Self Stimulation Behavior in the Runway Method
- Postnatal Blocking of Interferon-γ Function Prevented Atherosclerotic Plaque Formation in Apolipoprotein E-Knockout Mice
- Adenosine A_2A-Receptor Stimulation Inhibits Lipopolysaccharide-Induced Interleukin-18 Production in Monocytes
- Chronic Treatment with Imipramine and Lithium Increases Cell Proliferation in the Hippocampus in Adrenocorticotropic Hormone-Treated Rats
- Forced Exercise-Induced Flushing of Tail Skin in Ovariectomized Mice, as a New Experimental Model of Menopausal Hot Flushes
- Empirical Approach for Improved Estimation of Unbound Serum Concentrations of Valproic Acid in Epileptic Infants by Considering Their Physical Development
- Effect of Methamphetamine and Imipramine on Cerebral Ischemia-Induced Hyperactivity in Mongolian Gerbils
- Adenosine A2A-Receptor Stimulation Inhibits Lipopolysaccharide-Induced Interleukin-18 Production in Monocytes
- Evaluation of Effectiveness of New Infusion Set Equipped with an In-line Filter
- Counseling of Patients with Bronchial Asthma, and Clinical Pharmacy Practice and Education of Pharmacy School Students
- Neuroprotective Effect of TTC-909, an Isocarbacyclin Methyl Ester Incorporated in Lipid Microspheres, on Hippocampal Delayed Neuronal Death of Stroke-Prone Spontaneously Hypertensive Rats
- Histologicak Evience for Neuroprotective Action of Nebracetam on Ischemic Neuronal Injury in the Hippocampus of Stroke-Prone Spontaneously Hypertensive Rats
- Trimethylsilylated Chitosan : A Convenient Precursor for Chemical Modifications
- Effect of Diazepam on the Runway Method Using Priming Stimulation of Intracranial Self Stimulation Behavior
- The 5-HT_ Receptor Full Agonist, 8-OH-DPAT Inhibits ACTH-Induced 5-HT_ Receptor Hyperfunction in Rats : Involvement of 5-HT_ Receptors in the DOI-Induced Wet-Dog Shakes in ACTH-Treated Rats(Pharmacology)
- Increased DOI-Induced Wet-Dog Shakes in Adrenocorticotropic Hormone-Treated Rats Are Not Affected by Chronic Imipramine Treatment : Possible Involvement of Enhanced 5-HT_-Receptor Expression in the Frontal Cortex
- Determination of salicylic acid in human serum with capillary zone electrophoresis
- Clinical and Experimental Evidence for Prevention of Acute Renal Failure Induced by Radiographic Contrast Media
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs) : Role of Tryptase/PAR-2 in Vascular Endothelial Barrier Function
- Nafamostat Mesilate Is an Extremely Potent Inhibitor of Human Tryptase
- Motivational Effect of Nomifensine in the Intracranial Self-Stimulation Behavior Using a Runway Method(Pharmacology)
- Selegilin Exerts Antidepressant-Like Effects During the Forced Swim Test in Adrenocorticotropic Hormone-Treated Rats
- Motivational Effects of Methamphetamine as Measured by the Runway Method Using Priming Stimulation of Intracranial Self-stimulation Behavior(Analytical Biochemistry)
- Effects of Imipramine and Bupropion on the Duration of Immobility of ACTH-Treated Rats in the Forced Swim Test : Involvement of the Expression of 5-HT_ Receptor mRNA(Pharmacology)
- Effects of Long-Term Treatment With Calcium Antagonists on Periarterial Nerve Function in the Mesenteric Artery of Spontaneously Hyupertensive Rats
- Particulate Matter Analyses after Dissolution of Powder Antibiotic Injections Used in the Pediatric Ward
- Correlation between Cyclosporine Blood Concentration-Dose Ratio and Biochemical Parameters in Living-Donor Lung Transplant Patients
- Examination of Particulate Contamination after Opening Ampoules : Relationship between Ampoule Inner-diameter and Glass Particle Accumulation after Opening Ampoules
- Soybean Isoflavones Eliminate Nifedipine-Induced Flushing of Tail Skin in Ovariectomized Mice
- OE-077 Lacking the SOCS3 Gene in Macrophages Prevents the Development of Atherosclerosis in ApoE Deficient Mice(Atherosclerosis, basic-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PHARMACOLOGICAL CHARACTERISTICS OF ABNORMAL BEHAVIOR INDUCED BY HARMINE WITH SPECIAL REFERENCE TO TREMOR IN MICE
- Protective Action of Indapamide, a Thiazide-Like Diuretic, on Ischemia-Induced Injury and Barrier Dysfunction in Mouse Brain Microvascular Endothelial Cells
- Application of high-performance thin-layer chromatography for the detection of organophosphorus insecticides in human serum after acute poisoning
- Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of zonisamide
- Enhancement by Morphine of Radiographic Contrast Media-Induced Histamine Release in Rat Peritoneal Mast Cells
- Inhibitory Action of Nebracetam on Various Stimulti-Evoked Increases in Intracellular Ca^ Concentrations in Cultured Rat Cerebellar Granule Cells
- A Key Role of the Mammillary Body in Mediation of the Antianxiety Action of Zopiclone, a Cyclopyrrolone Derivative
- Involvement of Dopaminergic Receptor Signaling in the Effects of Glutamatergic Receptor Antagonists on Conditioned Place Aversion Induced by Naloxone in Single-Dose Morphine-Treated Rats
- Structural Optimization of the Antimicrobial Peptide Agent Omigard^ by Increasing its Activity as a Surfactant and the α-Helical Structure Ratio
- Effect of Pharmacist Management on Serum Hemoglobin Levels with Renal Anemia in Hemodialysis Outpatients
- Rapid and sensitive detection of benzodiazepines and zopiclone in serum using high-performance thin-layer chromatography
- Silylated Chitin:A New Organosoluble Precursor for Facile Modifications and Film Casting
- THE EMOTIONAL COMMUNICATION BASED ON METHAMPHETAMINE MORTALITY AS THE INDEX IN OLFACTORY BULBECTOMIZED MICE
- INFLUENCE OF AGGREGATION ON THE ACTION OF METHAMPHETAMINE IN LOCOMOTOR ACTIVITY
- Estrogen deficiency impairs sensitivity of the baroreceptor reflex and vasomotor functions in the aorta
- Tumor Necrosis Factor-α Mediates the Blood-Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells
- Involvement of Dopaminergic Receptor Signaling in the Effects of Glutamatergic Receptor Antagonists on Conditioned Place Aversion Induced by Naloxone in Single-Dose Morphine-Treated Rats
- Anandamide Induces Endothelium-Dependent Vasoconstriction and CGRPergic Nerve-Mediated Vasodilatation in the Rat Mesenteric Vascular Bed
- Quantitation and Human Monocyte Cytotoxicity of the Polymerization Agent 1-Hydroxycyclohexyl Phenyl Ketone (Irgacure 184) from Three Brands of Aqueous Injection Solution
- Cytotoxicity of the Polymerization Agent, 2-Methyl-4'-(methylthio)-2-morpholinopropiophenone on Human Monocytes
- Metabolomics Study on the Biochemical Profiles of Odor Elements in Urine of Human with Bladder Cancer
- CJK-P-17 Development of a Simple Suspension Method for New Drugs
- CJK-P-18 Cytotoxicity of Three Polymerization Agents on Human Monocytes
- The Mechanisms of Electroconvulsive Stimuli in BrdU-Positive Cells of the Dentate Gyrus in ACTH-Treated Rats
- Effects of MPC-1304, a Novel Calcium Antagonist, on Stroke-Prone Spontaneously Hypertensive Rats
- Expression of the Endothelin Receptors in the Hippocampus of SHRSP after Transient Forebrain Ischemia
- Evaluation of the neuroprotective action of WEB 1881 FU on hypoglycemia/hypoxia-induced neuronal damage using rat striatal slices.
- Specific Binding Sites for Endothelins in the Central Nervous System
- Behavioral and electroencephalographic effects of zopiclone, a cyclopyrrolone derivative.
- Localization and Characterization of Specific 125I-Brain Natriuretic Peptide (26) Binding Sites in Adrenal Gland and Kidney
- Inhibitory Effect of NMDA on Dopaminergic Transmission in a Slice Preparation of Rat Globus Pallidus.
- Paracellular Barrier and Tight Junction Protein Expression in the Immortalized Brain Endothelial Cell Lines bEND.3, bEND.5 and Mouse Brain Endothelial Cell 4
- Specific Binding Sites for Endothelin in the Brain, Spinal Cord, Heart and Kidney
- Nebracetam (WEB 1881FU) Prevents N-Methyl-D-Aspartate Receptor-Mediated Neurotoxicity in Rat Striatal Slices.
- 土-13-S23-1 Palliative care for patients by interdisciplinary team on outpatient cancer chemotherapy(International Symposium "Team Medical Care" "Pharmacists' Contribution to Medical Care",シンポジウム23)
- IN-02 A combination of chlorinated hydrocarbon and photoinitiator has increased cytotoxicity to human normal embryonic lung fibroblasts(International Poster)
- IN-01 Experiment of Cytotoxicity by methyl 2-benzoylbenzoateon human monocytes(International Poster)
- IN-04 Experiment of apoptosis by photoinitiators on human blood peripheral mononuclear cells(International Poster)
- The Mechanisms of Electroconvulsive Stimuli in BrdU-Positive Cells of the Dentate Gyrus in ACTH-Treated Rats