<原著>虚血性心疾患, 心不全における平均血小板容積及び血小板数の変動について

概要

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Mean platelet volume (MPV) and platelet count (PLT) were measured by a Coulter Counter Model S-Plus in normal subjects and the patients with myocardial infarction and congestive heart failure. No significant age-dependent changes were noticed in MPV and PLT in normal subjects. MPV and PLT exhibited significant negative correlations in normal subjects (r=-0.348,p<0.01), acute myocardial infarction (r=-0.344,p<0.05) and congestive heart failure (r=-0.357,p<0.01). MPV was significantly increased in old myocardial infarction (p<0.05) and congestive heart failure (p<0.01), while PLT was significantly decreased in acute myocardial infarction (p<0.05), old myocardial infarction (p<0.01) and congestive heart failure (p<0.001). After treatment, MPV decreased significantly both in acute myocardial infarction (p<0.01) and congestive heart failure (p<0.001) as compared with that at admission, while PLT increased significantly in congestive heart failure (p<0.05). These results indicate that the measurement of MPV and PLT is useful in understanding the pathophysiology and clinical course in patients with these cardiac diseases.
近畿大学の論文
1984-03-25