本態性高血圧症の心拍出量 : 重症度・循環諸因子との関係(B 臨床的研究)

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The resting cardiac output was measured by the earpiece dye-dilution method with an automatic calibration technique of dye in 539 out-patients with labile hypertension (67 cases) and essential hypertension. The latter was divided into 3 groups (mild, moderate, severe) by Tokyo University classification criteria of severity which consisted of 277,154 and 41 cases, respectively. Venous pressure (VP) was also measured. The values of cardiac output (CO) and stroke volume (SV) were evaluated by the indices of %CI and %SI, which represent the ratios of cardiac index and stroke index to the predicted agematched normal values. Labile hypertension showed significantly increased values of %CI (113.7±18.9%) and %SI (108.6±19.3%), while essential hypertension showed a definite tendency to decrease %CI and %SI with the severity of disease, i.e., 94.9±21.3%, 86.2±19.9%, and 75.0±16.2% for %CI and 93.6±22.3%, 88.3±23.8% and 75.7±22.1% for %SI, respectively. VP was not significantly increased with the severity. Cardiac involvement more closely related to CO than blood pressure elevation and cerebral involvement. Also, cardiac involvement most closely related to aging. VP was significantly decreased with cerebral involvement, suggesting that this finding would relate to the decrease in circulating blood volume. Although CI and SI significantly decreased with aging, %CI and %SI did not relate to aging. VP significantly decreased with aging, especially after 50 years old.
近畿大学の論文
1982-12-31

本態性高血圧症の心拍出量 : 重症度・循環諸因子との関係(B 臨床的研究)

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