<原著>本態性高血圧症患者の心拍出量, とくに重症度との関係

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The resting cardiac output was measured by the earpiece dye-dilution method with a newly devised automatic calibration technique of dye in 209 patients with labile hypertension (25 cases) and essential hypertension. The latter was divided into 3 groups, i. e., grades 1,2 and 3 in the increasing order of severity which consisted of 86,88 and 10 cases, respectively. The values of cardiac output and stroke volume were evaluated by the indices of % CI and % SI, which represent the ratios of cardiac index and stroke index to the predicted age-matched normal values. Labile hypertension showed significantly increased values of % CI (119.6 ± 15.6%) and % SI (114.7 ± 19.9%), while essential hypertension showed a definite tendency to decrease % CI and % SI with the severity of disease, i. e., 105.8 ± 19.5%, 98.8 ± 23.6% and 90.0 ± 31.2% for % CI and 1O7.1 ± 21.7%, 102.7 ± 28.1% and 80.6 ± 33.4% for % SI, respectively. Total peripheral resistance was significantly increased in parallel with the severity of disease. The cardiac index and stroke index significantly correlated to systolic pressure and pulse pressure in the mild group (grade 1) and severe group (grade 3), but they had no significant correlations to diastolic pressure. Thus, it was concluded that hemodynamics in the early state of essential hypertension is apparently hyperkinetic and even in the late state of hypertension cardiac output also makes a contribution to the maintenance of high blood pressure.
近畿大学の論文
1979-06-25

<原著>本態性高血圧症患者の心拍出量, とくに重症度との関係

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