Micronuclei Formation Induced by X-ray Irradiation Does Not Always Result from DNA Double-strand Breaks

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概要

• 論文の詳細を見る
• JRR Editorial Committeeの論文
• 2012-01-16

著者

• Watanabe Masami

  Particle Radiation Biology Research Reactor Institute Kyoto University

• Tano Keizo

  Particle Radiation Biology Res. Reactor Inst. Kyoto Univ.

• Tano K

  Kyoto Univ. Osaka Jpn

• Tano Keizo

  Laboratory Of Radiation Life Science Research Reactor Institute Kyoto University

• Tano Kaori

  Kyoto Univ.

• Tano Keizo

  Research Reactor Institute Kyoto Univ.

• Kashino Genro

  Particle Radiation Oncology Research Centre Research Reactor Institute Kyoto University

• Watanabe Masani

  National Institute Of Basic Biology (nibb)

• Watanabe Masami

  Laboratory Of Plant Nutrition Faculty Of Horticulture Chiba University

• Watanabe Masami

  京都大学原子炉実験所 粒子線生物学研究分野

• Kashino Genro

  京都大学原子炉実験所附属粒子線腫瘍学研究センター

• Watanabe Masani

  Division Of Radiation Biology Faculty Of Pharmacology Of Science Nagasaki University

• Watanabe Masami

  Lab. Of Radiation Biology Div. Of Radiation Life Sci. Res. Reactor Inst. Kyoto Univ.

• Kashino Genrou

  Particle Radiation Oncology Research Centre Research Reactor Institute Kyoto University

• Okada Takuya

  Laboratories For Nanobiology Graduate School Of Frontier Biosciences:formation Of Soft Nano-machines

• Takimoto Koichi

  Faculty Of Agriculture Yamaguchi University

• Takimoto Koichi

  Dept. Agric. Yamaguchi Univ.

• Kashino Genro

  Advanced Molecular Imaging Center Medical School Oita University

• Okada Takuya

  Laboratory Of Radiation Biology Research Reactor Institute Kyoto University

• NISHIURA Hideki

  Laboratory of Radiation Biology, Research Reactor Institute, Kyoto University

• Nishiura Hideki

  Laboratory Of Radiation Biology Research Reactor Institute Kyoto University

• TANO Keizo

  Laboratory of Radiation Biology, Research Reactor Institute, Kyoto University

関連論文

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• Identification of 8-oxoguanine-DNA Glycosylase/AP Lyase Activity in Extracts from Schizosaccharomyces pombe
• Disruption of the Schizosaccharomyces pombe homolog of MutY (SpMYH).
• Isolation and Characterization of SpMYH, a MutY Homolog, of Fission Yeast Schizosaccharomyces Pombe
• Increased Base Change Mutations at G:C Pairs in Escherichiacoli Deficient in Endonuclease III and VIII
• Radiation sensitivity of RAD54^, KU70^ and RAD54^/KU70^ mutants of the chicken DT40 cell line.
• Screening of inhibitors specific for homologous recombination using D40 cell lines.
• γ-ray Irradiation Enhanced Boron-10 Compound Accumulation in Murine Tumors
• A Simple and Rapid Method for Measurement of ^B-para-Boronophenylalanine in the Blood for Boron Neutron Capture Therapy Using Fluorescence Spectrophotometry
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• Mutational Specificity Induced by hydrogen peroxides in hypocatalacemic mouse cell strain and in kat mutant Escherichia coli
• Changes of mutatinal spectrum of supF gene by delayed transfection after riboflavin photosensitization
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• Mutational Specificity of SupF Gene Induced by Riboflavin-Photosensitization in Escherichia coli
• Formation of 8-hydroxyguanine and FapyGua in DNA by Riboflavin Mediated Photosensitization
• Mutational Specificity of the Ferrous Ion in a supF Gene of Endonuclease III/VIII Deficient Escherichia coli
• Analysis of DNA Damage and the Repair in D. radiodurans by Pulsed-Field Gel Flectrophoresis
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• Analysis on DNA Double Strand Breakage and the Repair in D.radiodurans by Pulsed-Field Gel Electrophoresis
• Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors : its Independency of p53 Status
• S-3-2 NHEJ pathway plays an important role in low dose-rate effects (LDRE)(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Establishment of the Screening System for Spontaneous and Radiation-Induced Mutation Frequency in the Chicken DT40 Cells
• Mutational Specificity Induced by Reactive Oxygen in Endonuclease III and VIII Deficient Escherichia coli.
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• The Relationship Between Residual Interphase Chromosome Breakage and Cellular Radiosensitivity in Transformed Syrian Golden Hamster Cells
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• Inhibition of repair of radiation-induced damage by mild temperature hyperthermia, referring to the effect on quiescent cell populations
• Effective Suppression of Bystander Effects by DMSO Treatment of Irradiated CHO Cells
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• Delayed Induction of Telomere Instability in Normal Human Fibroblast Cells by Ionizing Radiation
• 226 Radiation-induced delayed chromosomal instability caused by large deletion(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 223 Radiation-Induced Delayed Chromosomal Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 221 A Role of DNA Double Strand Break Repair in the Induction of Genetic Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 214 The complementation of abnormal phenotypes of Werner syndrome cells by expressing WRN gene(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-2-3 Radiation-Induced Delayed Chromosome Aberrations(Radiation Induced Genetical Instability : What Is the Mechanism That a Cell Memorizes Being Irradiated?, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Instability of a Human Chromosome Exposed to Radiation in Unirradiated Mouse Cells
• The Role of DNA-PKcs Function on Induction of Genetic Instability by Radiation
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• Evidence for Induction of DNA Double Strand Breaks in the Bystander Response to Targeted Soft X-Rays in Repair Deficient CHO Cells
• Increased Chromosome Instability and Accumulation of DNA Double-strand Breaks in Werner Syndrome Cells
• Biochemical Markers for in Situ Detection of DNA Double Strand Breaks in Cultured Mammalian Cells
• Exogenous Expression of Exonuclease Domain-deleted WRN Interferes with the Repair of Radiation-induced DNA Damages
• Differences in Effects of Oncogenes on Sensitivity to Anticancer Drugs
• Involvement of Reactive Oxygen Species (ROS) in the Induction of Genetic Instability by Radiation
• 225 Influence of Reactive Oxygen Species in the Induction of Genetic Instability by Radiation(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 222 X-ray-induced genomic instability in Atm knock-out mouse cells(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 220 Mechanism of radiation-induced delayed mutagenesis(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 217 Localization of Phosphorylated H2AX and Phosphorylated p53 in Cells Inducing X-ray-induced Senescence-like Growth Arrest(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 168 Mechanism of cell cycle-dependent cell death by heat shock(Radio-protection and sensitization, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 141 The role of site-specific phosphorylation on X-ray-induced p53 accumulation(Redox regulation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• An Alternative Mechanism for Radioprotection by Dimethyl Sulfoxide; Possible Facilitation of DNA Double-strand Break Repair
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• 97 A Role of WRN Protein in the Recovery from DNA Replication Arrest(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
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• Relationship between dysfunction of WRN protein and radiosensitivity
• Role of WRN exonuclease in repair of DNA double strand breaks
• Characterization of X-ray-induced Mutation in Werner Syndrome Cells
• Analysis of X-Ray-Induced Mutation in Werner Syndrome Cells
• Effect of introduction of a normal chromosome 8 on Werner syndrome cells
• Molecular analysis of mutations at the hprt locus in Werner syndrome cells by multiplex PCR
• Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors: its Independency of p53 Status
• Phosphorylated ATM Foci as a Biochemical Marker for DNA Double Strand Breaks
• Mechanism of radiation-induced delayed mutagenesis
• Delayed Induction of DNA Damage and Activation of p53 in X-ray Surviving Cells
• Participation of ATM function in X-ray-induced delayed chromosomal instability
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• Role of Ser15, Thr18, and Ser20 phosphorylation in p53 stabilization after X-irradiation
• X-rays-induced phosphorylation of H2AX in mitotic cells
• The role of telomerase activity in the radiation carcinogenesis processes of normal human cells
• In vitro transformation system using hTERT-transfected normal human diploid cells
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• Rate of Oxalate Biosynthesis from Glycolate and Ascorbic Acid in Spinach Leaves
• Radiation-induced long life-time radical which causes genetical effects
• An Alternative Mechanism for Radioprotection by Dimethyl Sulfoxide; Possible Facilitation of DNA Double-strand Break Repair
• 211 Effect of RibCys on scavenging long-lived radicals and reducing gene mutation in mammalian cells by adding AFTER irradiation(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Generation of intracellular reactive oxygen species during the isolation of Brassica napus leaf protoplasts
• Telomerase Activity, Telomere Length, and Chromosome Aberrations in the Extension of Life Span of Human Embryo Cells Induced by Low-dose X-rays
• S-6-2 Long-Lived Radicals (LLR) Causes Genotoxic Effects(Biological Effects of Long-lived Radicals Induced by Radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Mechanism of delayed mutagenesis by radiation-induced genomic instability
• Effects of Protein Kinase Inhibitors on the Accumulation Kinetics of p53 Protein in Normal Human Embryo Cells following X-irradiation
• Intervention of Oxygen-control Ability to Radiation Sensitivity, Cell Aging and Cell Transformation
• Delayed Cell Death, Giant Cell Formation and Chromosome Instability Induced by X-irradiation in Human Embryo Cells
• Micronuclei Formation Induced by X-ray Irradiation Does Not Always Result from DNA Double-strand Breaks

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