The Relationship Between Residual Interphase Chromosome Breakage and Cellular Radiosensitivity in Transformed Syrian Golden Hamster Cells

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Matsubara Sho

  Particle Radiation Oncology Research Center Research Reactor Institute Kyoto University

• Matsuura Shinya

  京都大学放射線生物研究センター

• Matsuura Shinya

  Department Of Radiation Biology Research Institute For Radiation Biology And Medicine Hiroshima Univ

• Suzuki M

  Particle Radiation Oncology Research Center Kyoto University

• INADA Tetsuo

  Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences

• MATSUBARA Sho

  Yokohama City Univ. School of MeD. Dep. of Radiol. Tokyo Med. &Dent. Univ. School of Dent. Dep. of R

• WATANABE Masami

  Nagasaki Univ.

• Watanabe M

  Laboratory Of Radiation Biology Research Reactor Institute Kyoto University

• Inada T

  Department Of Radiological Sciences Ibaraki Prefectural University Of Health Sciences

• Inada Tetsuo

  Ibaraki Prefectural Univ. Of Health Sci.

• Inada Tetsuo

  Institute Of Basic Medical Sciences University Of Tsukuba

• Inada Tetsuo

  Department Of Radiological Sciences Ibaraki Prefectural University Of Health Sciences

• KUBOTA Nobuo

  lbaraki Prefectural Univ. of Health Sciences

• Xin-Kang ZHU

  Yokohama City Univ.

• SUZUKI Masao

  Natl. Inst. Radiol. Sci.

• OZAWA Fujiko

  lbaraki Prefectural Univ. of Health Sciences

• INADA Tetsuo

  lbaraki Prefectural Univ. of Health Sciences

• Kubata Nobuo

  Ibaraki Prefectural Univ. Of Health Sci.

• Kubota N

  Department Of Radiological Sciences Ibaraki Prefectural University Of Health Sciences

• Kubota Nobuo

  Pola Chemical Industries Inc.

• Ozawa Fujiko

  Department Of Radiological Sciences Ibaraki Prefectural University Of Health Sciences

• Inada Tetsuo

  The Particle Radiation Medical Science Center University Of Tsukuba

• Kubota Nobuo

  Department Of Radiological Sciences. Ibaraki Prefectural University Of Health Sciences

• Suzuki Masao

  Heavy-ion Radiobiology Res. Group National Inst. Radiological Sciences

• Watanabe M

  Nagasaki University

• Matsubara Sho

  Yokohama City Univ. Dept. Radiol.

• Watanabe Masami

  京都大学原子炉実験所 粒子線生物学研究分野

• Watanabe Masani

  Division Of Radiation Biology Faculty Of Pharmacology Of Science Nagasaki University

• Matsubara Sho

  Yokohama City Univ. School Of Med. Dep. Of Radiol. Tokyo Med. &dent. Univ. School Of Dent. Dep.

• Matsubara Sho

  Dept. Of Radiology School Of Medicine Yokohama City Univ.

• Matsushita Satoru

  Department Of Technical Support And Development Natl. Inst. Radiol. Sci.

• Zhu Xin-Kang

  Yokohama City Univ.

関連論文

• LOH Analyses for Biological Effects of Space Radiation : Human Cell Culture in "Kibo" of International Space Station
• 242 Analysis of apoptosis induction in Nbs1 deficient cells(Apoptosis related, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 206 Functional Domain Analysis of NBS1 Gene in Homologous Recombinational Repair(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 98 Localization of Rad51 protein in cells from patients with Fanconi Anemia D1 group(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-3-1 Mechanisms of DNA double-strand break repair(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Mutation screening for a novel cancer-predisposition syndrome of total PCS
• p53-Binding Protein 1 (53BP1) is Involved in the Repair of DNA Double-Strand Breaks
• Analysis of the function of NBS1 in DNA double-strand break repair
• Histone H2AX regulates the formation of NBS1 foci on DNA damage sites
• Dissociation of ATM/NBS1 functions in telomere maintenance
• NBS1 is involved in recognition of DNA damage and initiation of homologous recombination.
• Bystander mutagenic effect of alpha particle in human-hamster hybrid cells
• Somatic Mutation Caused by Low Dose Rate Tritium Radiation : Studies Using A Hyper-sensitive DetectionSystem
• Complementation studies of immortalized cell lines from infants with total PCS
• Establishement of mouse Nbs1-deficient cell lines by gene targeting
• Association of cells from Fanconi anemia patients with radiation sensitivity
• The Effects of Boron Neutron Capture Therapy on Liver Tumors and Normal Hepatocytes in Mice
• Chromosome Breakage and Cell Lethality in Human Hepatoma Cells Irradiated with X rays and Carbon-ion Beams
• Oxidation of Atmospheric Molecular Tritium in Plant Leaves, Lichens and Mosses
• Association of DNA repair protein NBS1 with telomere maintenance
• The function of NBS1 and histone H2AX in the early process of DNA repair.
• Reversed dose-rate effect of high LET radiation in mutation induction
• Chromosomal instability syndrome of total premature chromatid separation with mosaic variegated aneuploidy is defective in mitotic spindle checkpoint
• Screening of protein interacting with FANCG by Yeast two-hybrid system
• The First Life Science Experiments in ISS : Reports of "Rad Gene"-Space Radiation Effects on Human Cultured Cells-
• Identification of a novel mRNA containing GADD45 exons
• γ-ray Irradiation Enhanced Boron-10 Compound Accumulation in Murine Tumors
• A Simple and Rapid Method for Measurement of ^B-para-Boronophenylalanine in the Blood for Boron Neutron Capture Therapy Using Fluorescence Spectrophotometry
• Evaluation of Hypoxia-specific Cytotoxic Bioreductive Agent-sodium Borocaptate-^B Conjugates as ^B-carriers in Boron Neutron Capture Therapy
• S-4-4 From Regionally Selective Radiotherapy to Cellular Selective Radiotherapy(Aiming Further Development of Radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• X-Ray Dose Enhancement Caused by the Addition of Gd-contrast Media and its Effect for Chromosome Aberration Efficiencies.
• Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors : its Independency of p53 Status
• The Relationship Between Residual Interphase Chromosome Breakage and Cellular Radiosensitivity in Transformed Syrian Golden Hamster Cells
• A Comparison of Biological Responses of Human Tumor Cells After Irradiation with Heavy Ions and Neutrons
• Response of human tumor cells in plateau phase and grown as spheroids to carbon beam irradiation.
• Four novel mutations of the Fanconi anemia group A gene (FAA) in Japanese patients
• Functionally important domain analysis of the Nijimegen breakage syndrome gene. NBS1
• Development of a Radio-sensitive Mutation System for the Study of Dose Rate Effects of Space High LET Radiation
• Inhibition of repair of radiation-induced damage by mild temperature hyperthermia, referring to the effect on quiescent cell populations
• Effective Suppression of Bystander Effects by DMSO Treatment of Irradiated CHO Cells
• Evaluation of Micronucleus Induction in Lymphocytes of Patients Following Boron-Neutron-Capture-Therapy : A Comparison with Thyroid Cancer Patients treated with radioiodine
• Effects of p53 Status and Wortmannin Treatment on Potentially Lethal Damage Repair, with Emphasis on the Response of Intratumor Quiescent Cells
• Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors : its independence of p53 status
• Development of Selective Irradiation Method to Blood Vessel
• NBS1, the Nijmegen breakage syndrome protein, regulates the localization of DNA repair complex hRAD50/hMRE11/NBS1
• Accelerated telomere shortening by disruption of DNA repair protein NBS1
• Construction of Nbs1 knockout cell line using chicken DT40
• Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
• The role of cytochrome c and mitochondria in the signal transduction pathway for radiation-induced apoptosis
• GADD45 and JNK/SAPK expressions following treatment of high osmolarity agent and γray in HeLa S3 cells
• Evaluation of Late Radiation Damage of Normal Tissues in Mouse Hind Legs after Irradiation with Carbon Beams
• RBE and Dose Distribution of Heavy Ion Beams.
• Cytosol extracted from irradiated cells induced DNA fragmentation
• Time Dependent Reduction of Skin Shrinkage in Mouse after Irradiation with the Falloff of Carbon Bragg Peak
• Dose response relations in acute cell death of pancreatic islets after irradiation of golden hamster with X-ray ,7OMeV proton and 290MeV carbon beams.
• Morphological Evaluation of Normal Tissue Damage after Neon Beam Irradiation in Mouse Hind Legs
• Evaluation of Normal Tissue Damage after Fractionated Irradiation of HIMAC Carbon- 12 in Mouse Hind Legs
• RBBs of 30MeV Fast Neutrons and 135MeV Carbon Beams for Clongenecities in Mouse Growing Tail Cartilage Cells.
• The effects of cell death and mutatlon induction lrradiated with acceterated carbon ion beams with spread out Bragg peak.
• Nijmegen Breakage Syndrome (NBS) gene, NBS1, is involved in telomeric length maintenance.
• Skin reaction after single doses of HIMAC Carbon-12 Spread- Out-Bragg-Peak
• Mutation Induction in Cultured Human Cells after Low-dose and Low-dose-rate γ-ray Irradiation : Detection by LOH Analysis
• Induction of LOH events by Low-dose or Low-dose Rate Radiation Exposure
• Relative Biological Effectiveness of the 235 MeV Proton Beams at the National Cancer Center Hospital East
• Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells
• Relative Biological Effectiveness of Accelerated Heavy Ions for Induction of Morphological Transformation in Syrian Hamster Embryo Cells
• Relative Biological Effectiveness of Accelerated Heavy Particles for Induction of In Vitro Transformation of Hamster Embryonic Cells.
• Mitochondrial Function Modulates Cytoplasmic Irradiation Induced Bystander Effect
• Effects of Irradiated Medium on Chromatid Aberrations in Mammalian Cells Using Double Mylar Dishes
• 127 Effects of Irradiated Medium on Chromatid Aberrations in Mammalian Cells(Effects of space radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Induction of a Bystander Chromosomal Damage of He-ion microbeams in Mammalian Cells
• Bystander chromosomal alterations induced in mammalian cells using a charged particle microbeam.
• Delayed Induction of Telomere Instability in Normal Human Fibroblast Cells by Ionizing Radiation
• Mapping of the underlying gene for rare genetic complementation group Fanconi anemia
• Neutron Generator (HIRRAC) and Dosimetry Study
• Development of a low energy proton irradiation system using HIRRAC
• NBS1 Regulates Apoptosis Induced by γ-Irradiation in Lymphoblastoid
• Mutation screening of the NBS1 gene in sporadic malignant lymphoma
• LET, cell cycle dependence for mutation induction and spectrum in HPRT locus
• Cell Cycle and LET Dependence for Radiation-induced Mutation : A Possible Mechanism for Reversed Dose-rate Effect
• Radiation-induced teratogenicity and embryo lethality in the scid mice.
• Mutation induction on normal human cells by split dose irradiation with carbon-ion beams
• Cell death on human cells by split dose irradiation with carbonion beams.
• Correlation between cell death and induction of non-rejoining PCC breaks irradiated by accelerated carbon-ion beams and X rays
• Morphometric Evaluation of Late Normal Tissue Damage after Neon Beam Irradiation in Mouse Hind Legs
• RBE of Heavy Ions (proton, carbon,neon) for Acute Cell Death of Pancreatic Islet Cells of the Golden Hamster(Mesocricetus auratus)
• Radiation-quality Dependent Cellular Response in Mutation Induction in Normal Human Cells
• LET and Ion-species Dependence for Mutation Induction and Mutation Spectrum on hprt Locus in Normal Human Fibroblasts
• 264 LET and Ion-species Dependence for Cell Killing and Mutation Induction in Normal Human Fibroblasts(Bases of radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• LET and Ion-species Dependence for Cell Killing and Mutation Induction in Normal Human Fibroblasts
• LET and Ion-species Dependence for Cell killing in Normal Human Fibroblasts.
• Genomic Instability in Mutation Induction on Normal Human Cells Exposed to Chronically Low-dose Radiation in Heavy-ion Radiation Field.
• Mutation Analysis of the Fanconi Anemia Gene FAA in Japanese patients
• Analysis of Biological Radiation Effects for Heavy Charged Particles - What is the physical quantity to specify those radiation quality -
• Function of NBS1 in Activation of ATM kinase in Response to IR.
• O-15. Chromosome instability and cancer predisposition in the PCS (premature chromatid separation) syndrome(Abstracts of the oral and poster presentations,Abstracts of the 55th Annual Meeting of the Society of Chromosome Research)
• O-11. The optimal conditions for cytological diagnosis of total premature chromatid separation (PCS), a novel cancer-prone genetic trait associated with mitotic checkpoint defect(Abstracts of the oral and poster presentations)(The 53rd Annual Meeting of t
• Morphological Evaiuation of Normal Tissue Damage after Carbon Beam Irradiation in Mouse Hind Legs
• A polymorphic CA repeat marker at the human 27-kD calbindin (CALB1) locus
• The relationship between NBS1 and cell death induced by γ-ray irradiation in lymphoblastoid

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