LOH Analyses for Biological Effects of Space Radiation : Human Cell Culture in "Kibo" of International Space Station

スポンサーリンク

概要

• 論文の詳細を見る
• 2009-05-01

著者

• YATAGAI Fumio

  RIKEN Institute

• TAKAHASHI Akihisa

  Nara Med. Univ.

• HONMA Masamitsu

  Natl. Inst. Health Sci.

• SUZUKI Hiromi

  Japan Space Forum

• OMORI Katsunori

  Japan Aerospace Exploration Agency

• SEKI Masaya

  Kagoshima Univ. Grad. Sch.

• HASHIZUME Toko

  Kagoshima Univ. Grad. Sch.

• SHIMAZU Toru

  Japan Space Forum

• ENOMOTO Shuichi

  RIKEN Institute

• OHNISHI Takeo

  Nara Med. Univ.

• ISHIOKA Noriaki

  Japan Aerospace Exploration Agency

• 小野 公二

  京都大学原子炉実験所 粒子線腫瘍学研究センター

• 小野 公二

  京都大学原子炉実験所

• Ohnishi Ken

  Department Of Biology Nara Medical University

• Ohnishi Takeo

  姫路獨協大学 医療保健学部作業療法学科

• Ohnishi Takeo

  奈良県立医科大学 生物学

• Suzuki Minoru

  Particle Radiation Oncology Research Center Kyoto University

• OHNISHI Takeo

  Dept. Biol. Nara Med. Univ.

• Suzuki M

  Particle Radiation Oncology Research Center Kyoto University

• Ishioka N

  Iss Science Project Office Institute Of Space And Astronautical Science Japan Aerospace Exploration

• Ishioka Noriaki

  奈良県立医科大学 生物学

• Ishioka Noriaki

  National Space Development Agency Of Japan

• Ishioka Noriaki

  京都工芸繊維大学 工芸科学部応用生物学

• Suzuki Masao

  Kagoshima Univ. Grad. Sch.

• Seki Masaya

  Heavy-ion Radiobiology Research Group Research Center For Charged Particle Therapy National Institut

• Ono Koji

  Particle Radiation Oncology Research Center Kyoto University

• Ohnishi T

  Nara Medical Univ. Nara Jpn

• OKAICHI Kumio

  Nara Med. Univ.

• Ito Nobuhiko

  Laboratory Of Veterinary Radiology And Radiation Biology Department Of Veterinary Medicine Kitasato

• Omori Katsunori

  Institute Of Space And Astronautical Science Japan Aerospace Exploration Agency (jaxa)

• Omori Katsunori

  Department Of Space Biology And Microgravity Sciences And Iss Science Project Office Institute Of Sp

• Enomoto Shuichi

  Riken

• Yatagai Fumio

  Inst. Phys. Chem. Res.

• Yatagai Fumio

  Division Of Radioisotope Technology The Institute Of Physical And Chemical Research

• Yatagai Fumio

  Riken

• Yatagai Fumio

  Ri Inst. Phys. Chem. Res.

• Shimazu Toru

  Life Science Space Utilization & Res. Dept. Japan Space Forum

• Hoson T

  Iss Science Project Office Institute Of Space And Astronautical Science Japan Aerospace Exploration

• Suzuki Masao

  National Inst. Radiological Sci. Chiba Jpn

• Ishioka Noriaki

  Space Utilization Research Center National Space Development Agency Of Japan (nasda)

• Ishioka Noriaki

  Department Of Space Environmental Medicine Kagoshima University Graduate School Of Medical And Denta

• Ono Koji

  京都大学原子炉実験所附属粒子線腫瘍学研究センター

• Ono K

  Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University

• Suzuki Masao

  Heavy-ion Radiobiology Research Group Research Center For Charged Particle Therapy National Institut

• Hoshino Tomoki

  Graduate School Of Science Osaka Prefecture University

• Yatagai Fumio

  理化学研究所

• Honma M

  Division Of Genetics And Mutagenesis National Institute Of Health Sciences

• Ohnishi Takeshi

  Dept. Biology Nara Med. Univ.

• Takahashi A

  Department Of Biology Nara Medical University

• Takahashi Akihisa

  奈良県立医科大学 生物学

• Hoson Takayuki

  Space Environmental Medicine Kagoshima University Graduate School Of Medical And Dental Sciences

• Ohnishi Ken

  Dept. Biology Nara Med. Univ.

• Yatagai F

  Riken Institute

• Hoson Takayuki

  Osaka City Univ. Osaka Jpn

• Ohnishi Takeo

  Nara Medical University

• Ogura Koichi

  College Of Industrial Technology Nihon University

• Ohnishi Takeo

  Dept. Of Biol. Nara Medical Univ.

関連論文

• The first life science experiments in ISS: reports of "Rad Gene": space radiation effects on human cultured cells (Special issue: Biological effects of space radiation (part 2))
• An Approach to Estimate Radioadaptation from DSB Repair Efficiency
• LOH Analyses for Biological Effects of Space Radiation : Human Cell Culture in "Kibo" of International Space Station
• The First Life Science Experiments in ISS : Reports of "Rad Gene"-Space Radiation Effects on Human Cultured Cells-
• Response of osteoblasts and osteoclasts in regenerating scales to gravity loading
• Scale osteoblasts and osteoclasts sensitively respond to low-gravity loading by centrifuge
• The effect of artificial gravity on the morphogenesis of UV-irradiated Dict ostelium discoldeum cells.
• Preferential Inhibition of Nucleosome Assembly by (6-4) Photo products,
• Effect of Heavy Ion Beams from Cyclotron (TIARA) and Synchrotron (HIMAC) on Escherichia coil DNA Repair Deficient Mutants
• A Comparison of Biological Responses of Human Tumor Cells After Irradiation with Heavy Ions and Neutrons
• Japanese Red-Bellied Newts in Space - AstroNewt Experiment on Space Shuttle IML - 2 and Space Flyer Unit
• "Myo Lab" : A JAXA Cell Biology Experiment in "Kibo (JEM)" of the International Space Station
• C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO
• Bio-Assessment of RISK in Long-Term Manned Space Exploration : Cell Death Factors in Space Radiation and/or Microgravity : A Review
• No induction of interchromosomal recombination by X-ray on thymidine kinase gene in human lymphoblast TK6 and its derivative cells
• Mutation Induction in Cultured Human Cells after Low-dose and Low-dose-rate γ-ray Irradiation : Detection by LOH Analysis
• Induction of LOH events by Low-dose or Low-dose Rate Radiation Exposure
• Morphogenesis in cucumber seedlings is negatively controlled by gravity
• Inhibition of root elongation in microgravity by an applied electric field
• Morphagensis of Rice and Arabidopsis Seedlings in Space
• Growth and Development, and Auxin Polar Transport in Higher Plants under Microgravity Conditions in Space: BRIC-AUX on STS-95 Space Experiment
• Growth Regulation Mechanisms in Higher Plants under Microgravity Conditions - Changes in Cell Wall Metabolism
• Gravimorphogenesis of Cucurbitaceae plants: Development of peg cells and graviperception mechanism in cucumber seedlings
• Inhibition of root elongation in microgravity by an applied electric field
• STS-95 space experiment for plant growth and development, and auxin polar transport
• Inhibition of Root Elongation in Microgravity an Applied Electric Field
• Growth and Development, and Auxin Polar Transport in Higher Plants under Microgravity Conditions in Space:BRIC-AUX on STS-95 Space Experiment
• Morphogenesis of Rice and Arabidopsis Seedlings in Space
• DEVELOPMENTAL PATTERN OF PEG IN CUCUMBER SEEDLINGS AND ITS NEGATIVE CONTROL BY GRAVITY
• Mutation Induction in the rspL gene on an E. coli-B. subtilis shuttle vector by Space Flight on MIR
• Tumor Induction in Mice Locally Irradiated with Carbon Ions : A Retrospective Analysis
• Analysis of DNA damage checkpoint pathway in mammalian cells
• Cellular Responses after Heavy-ion Exposure
• Expression and localization of p53 and PARP in cultured mammalian cells exposed to accelerated Fe and Ar-ions
• Judgement on "Hit or Non-hit" by Time-Lapse Observations of CHO Cells Exposed to Accelerated Iron-ions.
• Analysis of Mutations in the Human HPRT Gene induced by High LET Heavy-ion Irradiation
• Time-Lapse Photographic Observation of CHO Cells Exposed to Accelerated Iron-Ions
• Mechanisms of Interphase-Death Induction for CHO Cells Exposed to Accelerated Heavy-Ions
• Skin Shrinkage Caused by Neon-20 and Carbon-12
• LET Dependence of Interphase Cell-Death Induction by Accelerated Heavy-Ions
• Dependence of Interphase Cell-Death Induction on LET Values of Accelerated Heavy-Ions
• Targeted Heavy-Ion Microbeam Irradiation of the Embryo But Not Yolk in the Diapause-Terminated Egg of the Silkworm, Bombyx mori, Induces The Somatic Mutation
• Biological effects of heavy-ion irradiation on DNA double-strand breaks repair deficient mutant cell line
• Response of Crypt Cell Survivals of Mouse Intestine after Fractionated Doses of Accelerated Carbon-Ion with Spread-Out Bragg Peak.
• Increase of mitotic indices in a human salivary gland tumor xenograft after irradiation with particle beams.
• Chromosome Aberrations Induced by Neon lon Beams Produced by RIKEN Ring Cyclotron in human lymphocytes of blood.
• Position Determination by Laser Marks of Biological Samples Placed on a Plastic Track Detector and Inactivation of B. subtilis Spores by a Single Heavy Ion
• Exploration of 'Over Kill Effect' of High-LET Ar-and Fe-ions by Evaluating the Fraction of Non-hit Cell and Interphase Death
• Sensitive Detection of LOH Events in a Human Cell Line after C-ion Beam Exposure
• Effect of a p53 codon 237 mutation on X-ray induced HPRT mutations
• Analysis of tk Mutation Induced by Low Dose Ionizing Radiation in Human Cells
• Contribution of mutant p53 protein to hyper recombination leading to enhancement of spontaneous mutation.
• p53 protein contributed to repair of double strand break
• p53 and p21 protein induction in TK6 and NS human lymphoblastoid cells after X-ray and heavy ion irradiations.
• Effect of Pre-irradiation by Small Dose Heavy-ions in Human Cells
• Judgement on "Hit or Non-Hit" for the Cells Exposed to High-LET Heavy-Ions (Fe,Ar)
• Analysis of Mutation Induced by Heavy-ion in Human HPRT Gene
• Mutation induction after low-dose carbon-ion beam irradiation of frozen human cultured cells
• Mutation induction in frozen human cultured cells caused by low-dose carbon ion irradiation
• Detection of Adaptive Response at Chromosome Level
• DNA PKcs-independent error-prone DNA end-joining pathway and its role in radiation-induced mutagenesis
• Development of an Airtight Recirculating Zooplankton Culture Device for Closed Ecological Recirculating Aquaculture System (CERAS)
• Mutation Induction by Heavy-ion irradiation of gpt Δ Transgenic Mouse
• A fate of DNA double strand breaks in mammalian cells
• Effect of Space Flight on the Frequency of Micronuclei and Expression of Stress-responsive Proteins in Cultured Mammalian Cells
• Transport of Trace Elements through the Hyphae of an Arbuscular Mycorrhizal Fungus into Marigold Determined by the Multitracer Technique
• Growth and Development in Arabidopsis thaliana through an Entire Life Cycle under Simulated Microgravity Conditions on a Clinostat
• Growth and Cell Wall Properties in Hypocotyls of Arabidopsis tua6 Mutant under Microgravity Conditions in Space
• The Outline and Significance of the Resist Wall Experiment : Role of Microtubule-Membrane-Cell Wall Continuum in Gravity Resistance in Plants
• Coupling of ICP-MS and Multitracer Technique as a New Method to Investigate Dynamics of Various Elements in Soil-water System
• Animal Habitats for Space Experiments
• Preparation and Outline of Space-Based Studies on Gravity Responses and Cell Wall Formation in Plants
• Germination and Growth Test in Four Strains of Arabidopsis thaliana in the Reference Model of European Modular Cultivation System
• Introduction to The Proposed Space Experiments Aboard The ISS Using The Silkworm, Bombyx mori
• Expression of p53-Regulated Genes in Cultured Mammalian Cells After Exposure to A Space Environment
• JAXA Space Plant Research on the ISS with European Modular Cultivation System
• Reverse Genetic Approach to Exploring Genes Responsible for Cell-Wall Dynamics in Supporting Tissues of Arabidopsis thaliana under Microgravity Conditions
• Comparison of Oxidative Enzyme Activity in Motoneurons between the Cervical and Lumbar Segments in the Rat Spinal Cord after Spaceflight and Recovery
• Optical microscopy of Arabidopsis seedlings fixed in non-fresh FAA using Kennedy Fixation Tubes(1)
• Effects of running exercise during recovery from hindlimb unloading on soleus muscle fibers and their spinal motoneurons in rats
• A Spaceflight Experiment for the Study of Gravimorphogenesis and Hydrotroposm in Cucumber Seedlings
• EXPERIENCE AND LESSON LEARNED FROM INTERNATIONAL SELECTION OF SPACE LIFE SCIENCES EXPERIMENT
• Control of gravimorphogenesis by auxin: accumulation pattern of CS-IAA1 mRNA in cucumber seedlings grown in space and on the ground
• Ground Based Verification of JAXA Hardware for Life Science Experiments
• Distinct gene expression profiles in the femora of rats exposed to spaceflight, tail-suspension and denervation
• Glycerol-induced restoration of mutant p53 to normal p53 activity after radiation/heat treatment
• Microcystin-LR is not Mutagenic in vivo in the λ/lacZ Transgenic Mouse (Muta^ Mouse)
• Restoration of Mutant p53 to Normal p53 Activity by Glycerol
• OUTLINE OF PREVIOUS PLANT EXPERIMENTS UNDER MICROGRAVITY
• Short-term hypergravity does not affect protein-ubiquitination and proliferation in rat L6 myoblastic cells
• Induction of HSP72 by DNA damaging agents
• Growth and development, and auxin polar transport of transgenic Arabidopsis under simulated microgravity conditions on a three-dimensional clinostat
• Suitable Experimental Design for Determination of Auxin Polar Transport in Space Using a Spaceecraft
• Genotoxicity of microcystin-LR in vitro and in vivo
• Expression of p53-Regulated Proteins in Human Cultured Lymphoblastoid TSCE5 and WTK1 Cell Lines during Spaceflight
• Prostaglandin E Increases Both Osteoblastic and Osteoclastic Activity in the Scales and Participates in Calcium Metabolism in Goldfish
• Gastric acid induces mitochondrial superoxide production and lipid peroxidation in gastric epithelial cells
• Expression of p53-Regulated Proteins in Human Cultured Lymphoblastoid TSCE5 and WTK1 Cell Lines during Spaceflight
• Space Habitation and Microbiology: Status and Roadmap of Space Agencies

もっと見る 閉じる

スポンサーリンク