Nijmegen Breakage Syndrome (NBS) gene, NBS1, is involved in telomeric length maintenance.

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Matsuura Shinya

  Particle Radiation Oncology Research Center Research Reactor Institute Kyoto University

• Komatsu Kenshi

  Dept. Radiat. Biol. Res. Inst. Radiat. Biol. Med. Hiroshima Univ.

• Komatsu K

  Hiroshima Univ. Hiroshima Jpn

• Kobayashi Junya

  京都大学放射線生物研究センター ゲノム動態研究所

• Matsuura Shinya

  Res. Inst. Rad. Biol. Med. Hiroshima Univ.

• Matsuura Shinya

  京都大学放射線生物研究センター

• Matsuura Shinya

  Department Of Radiation Biology Research Institute For Radiation Biology And Medicine Hiroshima Univ

• Kamiya K

  Department Of Genome Repair Dynamics Radiation Biology Center Kyoto University

• TAUCHI Hiroshi

  Dept. Environ. Sci., Ibaraki Univ.

• NAKAMURA Asako

  Dept. Genome Repair Dynam., RBC, Kyoto Univ.

• IDE Toshinori

  Dept. Cell. Mol. Biol., Hiroshima Univ.

• KOBAYASHI Jyunya

  Dept. Oral. Radiol., Hiroshima Univ. Dent. Sch.

• Shinya Matsuura

  Res. Inst. Rad. Biol. Med. Hiroshima Univ.

• Komatsu K

  Department Of Genome Repair Dynamics Radiation Biology Center Kyoto University

• Tauchi Hiroshi

  Department Of Biological Science Faculty Of Science Ibaraki University

• Tauchi Hiroshi

  Dep. Env. Sci. Fac. Sci. Ibaraki Univ.

• Komatsu Kenshi

  Dep. Of Genome Repair Dynamics Radiation Biology Center Kyoto Univ.

• Komatsu Kenshi

  Department Of Radiation Biology Research Institute For Radiation Biology And Medicine Hiroshima Univ

• MASTUURA Shinya

  Dept. of Rad. Biol., Hiroshima Univ.

• TSUYAMA Naohiro

  Dept. of Cell, and Mol. Biol., Hiroshima Univ.

• Tauchi Hiroshi

  Dept. Environ. Sci. Ibaraki Univ.

• Tauchi Hiroshi

  Dep. Of Biological Sci. Fac. Of Sci. Ibaraki Univ.

• Tauchi Hiroshi

  Div. Environ. Biol. Res. Inst. Rad. Biol. And Med. Hiroshima University

• Masunaga Shin-ichiro

  Particle Radiation Oncology Research Center Research Reactor Institute Kyoto University

• Nakamura Asako

  Dept. Genome Repair Dynam. Rbc Kyoto Univ.

• Ide Toshinori

  Dept. Cell. Mol. Biol. Hiroshima Univ.

• Tsuyama Naohiro

  Dept. Of Cellular And Molecular Biol. Hiroshima Univ. School Of Medicine

• Komatsu Kenshi

  Dept. Radiat. Biol. Res. Inst. For Radiat. Biol. Med. Hiroshimauniv.

• Komatsu Kenshi

  Div. Of Environ. Biol. Res. Inst. Rad. Biol. Med. Hiroshima University.

• Komatsu Kenshi

  Dept. Genome Repair Dynamics Rad. Biol. Center Kyoto Univ.

• Tauchi Hiroshi

  Tokyo Institute Of Technology Research Laboratory For Nuclear Reactors

関連論文

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• Two Major Factors Involved in the Reverse Dose-rate Effect for Somatic Mutation Induction are the Cell Cycle Position and LET Value
• 242 Analysis of apoptosis induction in Nbs1 deficient cells(Apoptosis related, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 206 Functional Domain Analysis of NBS1 Gene in Homologous Recombinational Repair(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 182 Effect of gravity stress on homologous recombination(Environmental effects of radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 98 Localization of Rad51 protein in cells from patients with Fanconi Anemia D1 group(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 19 Analysis of Mutation Induction By Low Dose Rate Tritium Radiation Using Hyper Sensitive Detection System(Low dose and low dose-rate effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-3-1 Mechanisms of DNA double-strand break repair(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
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• Mutation screening for a novel cancer-predisposition syndrome of total PCS
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• Analysis of the function of NBS1 in DNA double-strand break repair
• Histone H2AX regulates the formation of NBS1 foci on DNA damage sites
• Dissociation of ATM/NBS1 functions in telomere maintenance
• NBS1 is involved in recognition of DNA damage and initiation of homologous recombination.
• The relationship between the minimally deleted region of the mouse chromosome 2 and the murine acutemyeloid leukemia development.
• Bystander mutagenic effect of alpha particle in human-hamster hybrid cells
• Somatic Mutation Caused by Low Dose Rate Tritium Radiation : Studies Using A Hyper-sensitive DetectionSystem
• Complementation studies of immortalized cell lines from infants with total PCS
• Establishement of mouse Nbs1-deficient cell lines by gene targeting
• Association of cells from Fanconi anemia patients with radiation sensitivity
• Estimation of Dose Absorbed Fraction for ^I-bera rays in Rat Thyroid
• Induction of dominant lethality and teratogenesis in F_1 mice following paternal ^Cf neutron-irradiation at pre-meiotic and post-meiotic stages of germ cells.
• Association of DNA repair protein NBS1 with telomere maintenance
• The function of NBS1 and histone H2AX in the early process of DNA repair.
• Reversed dose-rate effect of high LET radiation in mutation induction
• Chromosomal instability syndrome of total premature chromatid separation with mosaic variegated aneuploidy is defective in mitotic spindle checkpoint
• Screening of protein interacting with FANCG by Yeast two-hybrid system
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• The Relationship Between Residual Interphase Chromosome Breakage and Cellular Radiosensitivity in Transformed Syrian Golden Hamster Cells
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• Four novel mutations of the Fanconi anemia group A gene (FAA) in Japanese patients
• Functionally important domain analysis of the Nijimegen breakage syndrome gene. NBS1
• Development of a Radio-sensitive Mutation System for the Study of Dose Rate Effects of Space High LET Radiation
• NBS1, the Nijmegen breakage syndrome protein, regulates the localization of DNA repair complex hRAD50/hMRE11/NBS1
• Accelerated telomere shortening by disruption of DNA repair protein NBS1
• Construction of Nbs1 knockout cell line using chicken DT40
• Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
• The role of cytochrome c and mitochondria in the signal transduction pathway for radiation-induced apoptosis
• GADD45 and JNK/SAPK expressions following treatment of high osmolarity agent and γray in HeLa S3 cells
• Evaluation of Late Radiation Damage of Normal Tissues in Mouse Hind Legs after Irradiation with Carbon Beams
• RBE and Dose Distribution of Heavy Ion Beams.
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• Nijmegen breakage syndrome : Sequence analysis of an 800-kb genomic region on chromosome 8q21.
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• Recovery of heat inactivated DNA-PK activity and repair of DNA double strand break
• Sensitivity of Heavy-Ion Beam in Scid Mouse Lung Fibroblast Cells.
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• Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome
• Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome.
• Thermosensitivity and Thermotolerance of Scid Mouse Lung Fibroblast Cells.
• Effect of Low Dose Irradiation on the ConA Response of Mouse Splenic Lymphocytes
• Radiation-induced HPRT mutation of a radiation sensitive hamster cell line irs1SF
• DNA-dependent protein kinase restores mouse scid mutation
• Inhibition of radiation-induced oncogenic transformation in C3H10T1/2 cells by green tea component, (-)-epigallocatechin gal late.

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