Recovery of heat inactivated DNA-PK activity and repair of DNA double strand break

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Komatsu Kenshi

  Dept. Radiat. Biol. Res. Inst. Radiat. Biol. Med. Hiroshima Univ.

• OKUMURA Yutaka

  Dept. of Radiation Biophysics, Nagasaki Univ. , Sch. Med.

• IHARA Makoto

  Dept. of Biol, Nara Med. Univ.

• Okaichi Kumio

  Department Of Radiation Biophysics Atomic Bomb Disease Institute Nagasaki University Graduate School

• Okaichi K

  Nagasaki Univ. Graduate School Of Biomedical Sci. Nagasaki Jpn

• Okaichi Kumio

  Department Of Radiation Biophysics Radiation Effect Research Unit Atomic Bomb Disease Institute Naga

• Shimasaki Tatsuya

  Ri Center Kumamoto Univ.

• OKAICHI Kumio

  Dept. Rad. Bioph. Sch. Med. Nagasaki Univ.

• SHIMASAKI Tatsuya

  Dept. of Radiat. Biophys. , Atomic Disease Inst. Nagasaki Univ. Schi. of Med.

• Okaichi Kumio

  長崎大学医学部附属原爆後障害医療研究施設 腫瘍･診断病理学

• Ihara Makoto

  Department Of Radiation Biophysics Radiation Effect Research Unit Atomic Bomb Disease Institute Naga

• Ihara Makoto

  Dept. Of Radiat. Biophys. Nagasaki Univ. Sch. Med.

• Ihara M

  Fujitsu Lab. Ltd. Atsugi

• Okumura Y

  Department Of Radiation Biophysics Radiation Effect Research Unit Atomic Bomb Disease Institute Naga

• Okumura Yutaka

  Radiation Biophysics Atomic Bomb Sisease Inst. Nagasaki Univ.

• Okumura Yutaka

  Dept. Of Radiation Biophys. Atomic Bomb Disease Institute Nagasaki University School Of Medicine

• Ihara Makoto

  Department Of Radiation Biophysics Atomic Disease Institute Nagasaki Univ. School Of Med.

• Komatsu Kenshi

  Dept. Radiat. Biol. Res. Inst. For Radiat. Biol. Med. Hiroshimauniv.

• Simasaki Tatsuya

  Dep. Radiation Biophys. Nagasaki Univ. School Med.

• Komatsu Kenshi

  Dept. Genome Repair Dynamics Rad. Biol. Center Kyoto Univ.

関連論文

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• 誘発突然変異と損傷乗り越えDNA合成を制御するPCNAのモノユビキチン化反応の解析 (第50回原子爆弾後障害研究会 特集号)
• Two Major Factors Involved in the Reverse Dose-rate Effect for Somatic Mutation Induction are the Cell Cycle Position and LET Value
• 242 Analysis of apoptosis induction in Nbs1 deficient cells(Apoptosis related, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 206 Functional Domain Analysis of NBS1 Gene in Homologous Recombinational Repair(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 182 Effect of gravity stress on homologous recombination(Environmental effects of radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 98 Localization of Rad51 protein in cells from patients with Fanconi Anemia D1 group(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 19 Analysis of Mutation Induction By Low Dose Rate Tritium Radiation Using Hyper Sensitive Detection System(Low dose and low dose-rate effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-3-1 Mechanisms of DNA double-strand break repair(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Analysis of the cell death after irradiation in the cells with defective DNA repair
• Mutation screening for a novel cancer-predisposition syndrome of total PCS
• p53-Binding Protein 1 (53BP1) is Involved in the Repair of DNA Double-Strand Breaks
• Analysis of the function of NBS1 in DNA double-strand break repair
• Histone H2AX regulates the formation of NBS1 foci on DNA damage sites
• Dissociation of ATM/NBS1 functions in telomere maintenance
• NBS1 is involved in recognition of DNA damage and initiation of homologous recombination.
• The relationship between the minimally deleted region of the mouse chromosome 2 and the murine acutemyeloid leukemia development.
• Bystander mutagenic effect of alpha particle in human-hamster hybrid cells
• Somatic Mutation Caused by Low Dose Rate Tritium Radiation : Studies Using A Hyper-sensitive DetectionSystem
• Complementation studies of immortalized cell lines from infants with total PCS
• Establishement of mouse Nbs1-deficient cell lines by gene targeting
• Association of cells from Fanconi anemia patients with radiation sensitivity
• Zuckerラットを用いた味噌による脂肪肝の減少効果
• Association of DNA repair protein NBS1 with telomere maintenance
• The function of NBS1 and histone H2AX in the early process of DNA repair.
• Reversed dose-rate effect of high LET radiation in mutation induction
• Chromosomal instability syndrome of total premature chromatid separation with mosaic variegated aneuploidy is defective in mitotic spindle checkpoint
• Screening of protein interacting with FANCG by Yeast two-hybrid system
• Mortality of A-bomb Survivors in RERF population
• Mortality of A-bomb Survivors in Nagasaki based on ABS93D
• Cause of Death of A-bomb survivors in Nagasaki at early times of A-bomb explosion
• Mortality by Cause of Death of Survivors in Nagasaki at Early Time of A-bomb Explosion.
• Increase of wtp53 pool size in specific organs of mice by low doses of X-ray.
• Functionally important domain analysis of the Nijimegen breakage syndrome gene. NBS1
• Development of a Radio-sensitive Mutation System for the Study of Dose Rate Effects of Space High LET Radiation
• NBS1, the Nijmegen breakage syndrome protein, regulates the localization of DNA repair complex hRAD50/hMRE11/NBS1
• Accelerated telomere shortening by disruption of DNA repair protein NBS1
• Construction of Nbs1 knockout cell line using chicken DT40
• Norepinephrine Enhances Radiosensitivity in Rat Ileal Epithelial Cells
• Nijmegen Breakage Syndrome (NBS) gene, NBS1, is involved in telomeric length maintenance.
• Loss of p53 -dependent signal transdution in γ -ray irradiated scid mouse fibroblasts
• Positional cloning of the gene for Nijmegen breakage syndrome
• Genetic Mapping of Nijmegen Breakage Syndrome using Functional Complementation Assays and Homozygosity Mapping
• Haplotype Analysis of Nijmegen Breakage Syndrome and Construction of Physical Map of Candidate Region.
• Complementation Assay between Radiation-Sensitive irs2 Mutant and Ataxia-Telangiectasia Cell
• The Genetic Homogeneity of Nijmegen Breakage Syndrome V1 and V2.
• Sensitivity to Ionizing Radiation in Saos-2 Cells Transfected with Mutant p53 Genes Depends on the Mutation Position
• Mutation-points of p53 affect the sensitivity of the cell to anticancer drugs.
• The sensitivity to ionizing radiation and radiation-induced apoptosis in Saos-2 cells transfected by four mutants and wild typc p53.
• How will a mutation of p53 affect the sensitivity of the cell to ionizing radiation.
• Mapping of the underlying gene for rare genetic complementation group Fanconi anemia
• NBS1 Regulates Apoptosis Induced by γ-Irradiation in Lymphoblastoid
• Mutation screening of the NBS1 gene in sporadic malignant lymphoma
• LET, cell cycle dependence for mutation induction and spectrum in HPRT locus
• Radiation-induced internal developmental abnormalities in scid mice
• Cell growth and morphology of Dictyostelium discoideum in space environment
• Cell growth and morphology of Dictyostelium discoideum in space environment
• Mutation Analysis of the Fanconi Anemia Gene FAA in Japanese patients
• Mutation Analysis of the Fanconi Anemia Genes in Japanese Patients
• Function of NBS1 in Activation of ATM kinase in Response to IR.
• Protection by Polaprezinc Against Radiation-Induced Apoptosis in Rat Jejunal Crypt Cells
• Sucralfate Protects Intestinal Epithelial Cells from Radiation-Induced Apoptosis in Rats
• The Protective Effect of Fermented Milk Kefir on Radiation-induced Apoptosis in Colonic Crypt Cells of Rats
• The protective effect of a fermented milk Kefir to radiation-induced apoptosis in rat colon
• Introduction of a normal chromosorne 8 into Werner syndrome cells by microcell fusion
• The suppression effect of sucralfate and soduim butyrate on radiation-induced apoptosis
• Induction of chromosome aberrations by a combined treatment with radiation and heat
• Heat sensitivity of DNA-dependent protein kinase activity
• The Role of the Sympathetic Nervous System in Radiation-induced Apoptosis in Jejunal Crypt Cells of Spontaneously Hypertensive Rats
• Acute Irradiation Injury and Autonomic Nervous System
• The genetic complementation assay of Nijmegen breakage syndrome witit ataxia telangiectasia on the basis of radiation sensitivity to cell killing.
• Development of Malignant Tumors following Irradiation for Preexisting Tumors:Study Based on Autopsy Cases of Double Cancer
• The phosphatidylinositol 3-kinase, inhibited by low dose of wortmannin, affects radiation sensitivity
• RBE for scid cells irradiated with high LET radiations
• Nijmegen breakage syndrome : Sequence analysis of an 800-kb genomic region on chromosome 8q21.
• A mutant human p53, 123A, which led to apoptosis but not Waf-1 in response to ionizing radiation in a human osteosarcoma cell line, Saos-2
• The scid factor on human chromosome 8 restores both V(D)J recombination and double-strand break repair
• The relationship between NBS1 and cell death induced by γ-ray irradiation in lymphoblastoid
• Cell cycle and LET dependence for 6-thioguanine-resistant mutation induced by heavy ion beam in mouse L5178Y cells
• Hypergravity Induces Phosphorylation of p53 at Serine 15, but not an Expression of p53-downstream Genes
• 128 Analysis of gene expression induced by hypergravity using DNA chip(Effects of space radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Accumulation and phosphorylation of p53 by hypergravity
• Hypergravity Modifies the Signal Transduction of Ionizing Radiation through p53
• Cross talk of p53 signal pathway by low dose radiation and artificial gravity
• Phosphorylation of p53 by low dose X-ray irradiation
• Recovery of heat inactivated DNA-PK activity and HSC73
• Recovery of heat inactivated DNA-PK activity and repair of DNA double strand break
• Efficient Trap of a Coaxial Gun Plasma in an Axisymmetric Mirror with an Internal Hoop
• RBE of Scid Cells for Heavy Ions.
• Sensitivity of Heavy-Ion Beam in Scid Mouse Lung Fibroblast Cells.
• Thermosensitivity and DNA-PK activity of scid cells and hybrid scid cells containing human chromosome 8
• Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome
• Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome.
• Quantification of radiation-induced aging using senescense accelerated mouse
• Norepinephrine Enhances Radiosensitivity in Rat Ileal Epithelial Cells
• Thermosensitivity and Thermotolerance of Scid Mouse Lung Fibroblast Cells.
• Effect of Low Dose Irradiation on the ConA Response of Mouse Splenic Lymphocytes
• Effect of Low Dose Irradiation on the ConA Response of Mouse Splenic Lymphocytes (II)
• Effects of Repeated Irradiation on a Biological Response with High Sensitivity to Exposure (IV)
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