Cell cycle and LET dependence for 6-thioguanine-resistant mutation induced by heavy ion beam in mouse L5178Y cells
スポンサーリンク
概要
著者
-
Matsuura Shinya
Particle Radiation Oncology Research Center Research Reactor Institute Kyoto University
-
Komatsu Kenshi
Dept. Radiat. Biol. Res. Inst. Radiat. Biol. Med. Hiroshima Univ.
-
Kamiya K
Department Of Genome Repair Dynamics Radiation Biology Center Kyoto University
-
TAUCHI Hiroshi
Dept. Environ. Sci., Ibaraki Univ.
-
MATSUURA Shinya
Dept. Genome Repair Dynam., RBC, Kyoto Univ.
-
安藤 興一
学振科技特
-
Shinya Matsuura
Res. Inst. Rad. Biol. Med. Hiroshima Univ.
-
EGUCHI-KASAI Kiyomi
NIRS
-
FURUSAWA Yoshiya
National Institute of Radiological Sciences
-
Futami Yasuyuki
茨城県立医療大学 放射線技術科学科
-
Futami Yasuyuki
Dvisin Of Accelerator Physics And Engineering National Institite Of Radiological Sciences Chiba Japa
-
遠藤 暁
Mechanical System Engineering Graduate School Of Engineering Hiroshima University
-
Endo Satoru
Department Of Biochemistry Cancer Institute Okayama University Medical School
-
SUZUKI Masao
Natl. Inst. Radiol. Sci.
-
Komatsu Kenshi
Dep. Of Genome Repair Dynamics Radiation Biology Center Kyoto Univ.
-
SUGA SHINJI
Research Institute for Radiation Biology and Medicine, Hiroshima University
-
Suga Shinji
Research Institute For Radiation Biology And Medicine Hiroshima University
-
Eguchi‐kasai K
National Inst. Radiological Sci. Chiba Jpn
-
Eguchi Kasai
Research Center For Radiation Protection National Institute Of Radiological Sciences
-
Kasai Kiyomi
Division Of Radiobiology & Biodosimetry National Institute Of Radiological Sciences
-
EGUCHI-KASAI Kiyomi
Natl. Inst. Radiol. Sci.
-
ENDO Satoru
Dept. of Rad. Biol. , RIRBM. , Hiroshima Univ.
-
Tauchi Hiroshi
Dept. Environ. Sci. Ibaraki Univ.
-
Ando Koichi
Department Of Technical Support And Development Natl. Inst. Radiol. Sci.
-
Suzuki Masao
Heavy-ion Radiobiology Res. Group National Inst. Radiological Sciences
-
Endo Satoru
Div. Environ. Biol. Res. Inst. Rad. Biol. And Med. Hiroshima University
-
Ando Koichi
Division Of Health Sciences Graduate School Of Medicine Osaka University
-
Shoji Syuneki
Department Of Environment And Mutation Research Institute For Radiation Biology And Medicine
-
Furusawa Yoshiya
高エネルギー加速器研究機構物質構造科学研究所
-
Sawada S
Department Of Electronic Engineering College Of Science And Engineering Iwaki Meisei University
-
Sawada S
Iwaki Meisei Univ. Fukushima‐ken
-
Sawada Shozo
Department Of Applied Physics Chubu Institute Of Technology
-
Sawada Shozo
Department Of Physics College Of Science Tokyo Institute Of Technology
-
FRUSAWA Yoshiya
Natl. Inst. of Radiological Sciences
-
AND0 Koichi
Natl. Inst. of Radiological Sciences
-
SWADA Shozo
Hiroshima Pref. Col. Health and Welfare.
-
Sawada S
Research Institute For Radiation Biology And Medicine Hiroshima University
-
Komatsu Kenshi
Dept. Radiat. Biol. Res. Inst. For Radiat. Biol. Med. Hiroshimauniv.
-
Komatsu Kenshi
Dept. Genome Repair Dynamics Rad. Biol. Center Kyoto Univ.
-
Tauchi Hiroshi
Tokyo Institute Of Technology Research Laboratory For Nuclear Reactors
関連論文
- 血中コレステロールと味噌--味噌食が食事性代謝障害に及ぼす影響の研究
- 誘発突然変異と損傷乗り越えDNA合成を制御するPCNAのモノユビキチン化反応の解析 (第50回原子爆弾後障害研究会 特集号)
- Two Major Factors Involved in the Reverse Dose-rate Effect for Somatic Mutation Induction are the Cell Cycle Position and LET Value
- 242 Analysis of apoptosis induction in Nbs1 deficient cells(Apoptosis related, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- 206 Functional Domain Analysis of NBS1 Gene in Homologous Recombinational Repair(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- 182 Effect of gravity stress on homologous recombination(Environmental effects of radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- 98 Localization of Rad51 protein in cells from patients with Fanconi Anemia D1 group(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- 19 Analysis of Mutation Induction By Low Dose Rate Tritium Radiation Using Hyper Sensitive Detection System(Low dose and low dose-rate effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- S-3-1 Mechanisms of DNA double-strand break repair(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- Analysis of the cell death after irradiation in the cells with defective DNA repair
- Mutation screening for a novel cancer-predisposition syndrome of total PCS
- p53-Binding Protein 1 (53BP1) is Involved in the Repair of DNA Double-Strand Breaks
- Analysis of the function of NBS1 in DNA double-strand break repair
- Histone H2AX regulates the formation of NBS1 foci on DNA damage sites
- Dissociation of ATM/NBS1 functions in telomere maintenance
- NBS1 is involved in recognition of DNA damage and initiation of homologous recombination.
- The relationship between the minimally deleted region of the mouse chromosome 2 and the murine acutemyeloid leukemia development.
- Bystander mutagenic effect of alpha particle in human-hamster hybrid cells
- Somatic Mutation Caused by Low Dose Rate Tritium Radiation : Studies Using A Hyper-sensitive DetectionSystem
- Complementation studies of immortalized cell lines from infants with total PCS
- Establishement of mouse Nbs1-deficient cell lines by gene targeting
- Association of cells from Fanconi anemia patients with radiation sensitivity
- Estimation of Dose Absorbed Fraction for ^I-bera rays in Rat Thyroid
- Induction of dominant lethality and teratogenesis in F_1 mice following paternal ^Cf neutron-irradiation at pre-meiotic and post-meiotic stages of germ cells.
- Zuckerラットを用いた味噌による脂肪肝の減少効果
- 一般演題29 広島県内原爆被爆者の子供数
- Association of DNA repair protein NBS1 with telomere maintenance
- The function of NBS1 and histone H2AX in the early process of DNA repair.
- Reversed dose-rate effect of high LET radiation in mutation induction
- Chromosomal instability syndrome of total premature chromatid separation with mosaic variegated aneuploidy is defective in mitotic spindle checkpoint
- Screening of protein interacting with FANCG by Yeast two-hybrid system
- A Comparison of Biological Responses of Human Tumor Cells After Irradiation with Heavy Ions and Neutrons
- Four novel mutations of the Fanconi anemia group A gene (FAA) in Japanese patients
- Accumulation of Cells at G_2/M Stage by Low Dose-Rate Irradiation Renders the Cell Population More Susceptible to the Subsequent Induction of 6-Thioguanine-Resistant Mutations by ^Cf Fission Neutrons.
- 放射線誘発マウス肝癌におけるIGFBP-rP1遺伝子の役割
- 線維芽細胞成長因子受容体2(FGFR2IIIb)の発現回復によるヒト前立腺癌細胞の増殖抑制
- Functionally important domain analysis of the Nijimegen breakage syndrome gene. NBS1
- Development of a Radio-sensitive Mutation System for the Study of Dose Rate Effects of Space High LET Radiation
- NBS1, the Nijmegen breakage syndrome protein, regulates the localization of DNA repair complex hRAD50/hMRE11/NBS1
- Accelerated telomere shortening by disruption of DNA repair protein NBS1
- Construction of Nbs1 knockout cell line using chicken DT40
- 誘発突然変異と損傷乗り越えDNA合成 : REV1の構造と生化学的機能
- 損傷乗り越えDNA合成と発癌 (特集 DNAの損傷・修復と疾患)
- P054 Effect of REV1 on the survival of human cells after various DNA damages(Poster Session)
- W2-2 Effect of REV1 on the survival of human cells after various DNA damages(Workshop(2) : Translesion DNA Synthesis and Mutagenesis)
- 一般演題 2 広島大学「原爆・被ばく関連資料データベース」 の概要と公開の意義
- 放射線発がんのメカニズム (第46回原子爆弾後障害研究会) -- (シンポジウム 原子爆弾後障害研究の将来の展望--これからの10年間に期待される成果)
- シンポジウム-1 広島大学21世紀COEプログラム「放射線災害医療開発の先端的研究教育拠点-ゲノム障害科学に基づく学術基盤の確立と医療展開-」の概要
- マウス肝癌で発現が亢進している新規遺伝子 cis-retinol/androgen dehydrogenase type 3 (CRAD 3) の機能解析
- 一般演題 38 損傷乗り越えDNA合成に関与するヒトREV1タンパク質の生化学的解析
- 放射線誘発DNA損傷修復およびアポトーシスにおけるTIP60ヒストンアセチル化酵素複合体の役割
- マウス肝癌におけるIGFBP-7遺伝子の発現低下
- 誘発突然変異の分子機構
- 低線量被曝と発癌 : 乳癌を中心に
- Control of Ductal vs. Alveolar Differentiation of Mammary Clonogens and Susceptibility to Radiation-Induced Mammary Cancer
- Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
- Zuckerラットを用いた味噌による脂肪肝の減少効果
- Nijmegen Breakage Syndrome (NBS) gene, NBS1, is involved in telomeric length maintenance.
- Induction of dominant lethality and developmental anomalies in offspring of male mice inadiated to varying doses of ^Cf fission neutrons
- Loss of p53 -dependent signal transdution in γ -ray irradiated scid mouse fibroblasts
- Positional cloning of the gene for Nijmegen breakage syndrome
- Genetic Mapping of Nijmegen Breakage Syndrome using Functional Complementation Assays and Homozygosity Mapping
- Haplotype Analysis of Nijmegen Breakage Syndrome and Construction of Physical Map of Candidate Region.
- Complementation Assay between Radiation-Sensitive irs2 Mutant and Ataxia-Telangiectasia Cell
- The Genetic Homogeneity of Nijmegen Breakage Syndrome V1 and V2.
- Mapping of the underlying gene for rare genetic complementation group Fanconi anemia
- Effect of gravity stress on fidelity of DNA double-strand break repair
- Neutron Generator (HIRRAC) and Dosimetry Study
- Development of a low energy proton irradiation system using HIRRAC
- A biophysical estimate of radioactive iodine (^I) exposure in the whole body and in the thyroid of newborn, puberty and adult Fischer 344 rats.
- NBS1 Regulates Apoptosis Induced by γ-Irradiation in Lymphoblastoid
- Mutation screening of the NBS1 gene in sporadic malignant lymphoma
- LET, cell cycle dependence for mutation induction and spectrum in HPRT locus
- Cell Cycle and LET Dependence for Radiation-induced Mutation : A Possible Mechanism for Reversed Dose-rate Effect
- Radiation-induced internal developmental abnormalities in scid mice
- Radiation-induced teratogenicity and embryo lethality in the scid mice.
- Mutation Analysis of the Fanconi Anemia Gene FAA in Japanese patients
- Mutation Analysis of the Fanconi Anemia Genes in Japanese Patients
- Kinetics of Mammary Clonogenic Cells and Rat Mammary Cancer Induction by X-rays or Fission Neutrons
- Age-dependent Exposure to Radioactive Iodine (^I) in the Thyroid and Total Body of Newborn, Pubertal and Adult Fischer 344 Rats
- Function of NBS1 in Activation of ATM kinase in Response to IR.
- O-15. Chromosome instability and cancer predisposition in the PCS (premature chromatid separation) syndrome(Abstracts of the oral and poster presentations,Abstracts of the 55th Annual Meeting of the Society of Chromosome Research)
- O-11. The optimal conditions for cytological diagnosis of total premature chromatid separation (PCS), a novel cancer-prone genetic trait associated with mitotic checkpoint defect(Abstracts of the oral and poster presentations)(The 53rd Annual Meeting of t
- Heat sensitivity of DNA-dependent protein kinase activity
- The genetic complementation assay of Nijmegen breakage syndrome witit ataxia telangiectasia on the basis of radiation sensitivity to cell killing.
- Nijmegen breakage syndrome : Sequence analysis of an 800-kb genomic region on chromosome 8q21.
- The scid factor on human chromosome 8 restores both V(D)J recombination and double-strand break repair
- The relationship between NBS1 and cell death induced by γ-ray irradiation in lymphoblastoid
- Cell cycle and LET dependence for 6-thioguanine-resistant mutation induced by heavy ion beam in mouse L5178Y cells
- Recovery of heat inactivated DNA-PK activity and HSC73
- Recovery of heat inactivated DNA-PK activity and repair of DNA double strand break
- Sensitivity of Heavy-Ion Beam in Scid Mouse Lung Fibroblast Cells.
- Thermosensitivity and DNA-PK activity of scid cells and hybrid scid cells containing human chromosome 8
- Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome
- Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome.
- Thermosensitivity and Thermotolerance of Scid Mouse Lung Fibroblast Cells.
- Effect of Low Dose Irradiation on the ConA Response of Mouse Splenic Lymphocytes
- Radiation-induced HPRT mutation of a radiation sensitive hamster cell line irs1SF
- DNA-dependent protein kinase restores mouse scid mutation
- Inhibition of radiation-induced oncogenic transformation in C3H10T1/2 cells by green tea component, (-)-epigallocatechin gal late.