Thermosensitivity and DNA-PK activity of scid cells and hybrid scid cells containing human chromosome 8

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Komatsu Kenshi

  Dept. Radiat. Biol. Res. Inst. Radiat. Biol. Med. Hiroshima Univ.

• Komatsu Kenshi

  Res. Inst. For Radiation Biology And Medicine

• Okaichi Kumio

  Department Of Radiation Biophysics Atomic Bomb Disease Institute Nagasaki University Graduate School

• Okaichi K

  Nagasaki Univ. Graduate School Of Biomedical Sci. Nagasaki Jpn

• Okaichi Kumio

  Department Of Radiation Biophysics Radiation Effect Research Unit Atomic Bomb Disease Institute Naga

• Shimasaki Tatsuya

  Ri Center Kumamoto Univ.

• Okaichi Kumio

  長崎大学医学部附属原爆後障害医療研究施設 腫瘍･診断病理学

• Ihara Makoto

  Department Of Radiation Biophysics Radiation Effect Research Unit Atomic Bomb Disease Institute Naga

• Ihara Makoto

  Dept. Of Radiat. Biophys. Nagasaki Univ. Sch. Med.

• Ihara M

  Fujitsu Lab. Ltd. Atsugi

• Okumura Y

  Department Of Radiation Biophysics Radiation Effect Research Unit Atomic Bomb Disease Institute Naga

• Okumura Yutaka

  Radiation Biophysics Atomic Bomb Sisease Inst. Nagasaki Univ.

• IHARA Makoto

  Dept Radiation Biophys. , Nagasaki Univ. School Med.

• OKAICHI Kumio

  Dept Radiation Biophys. , Nagasaki Univ. School Med.

• SHIMASAKI Tatsuya

  Dept Radiation Biophys. , Nagasaki Univ. School Med.

• OKUMURA Yutaka

  Dept Radiation Biophys. , Nagasaki Univ. School Med.

• Ihara Makoto

  Department Of Radiation Biophysics Atomic Disease Institute Nagasaki Univ. School Of Med.

• Simasaki Tatsuya

  Dep. Radiation Biophys. Nagasaki Univ. School Med.

関連論文

• 98 Localization of Rad51 protein in cells from patients with Fanconi Anemia D1 group(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• p53-Binding Protein 1 (53BP1) is Involved in the Repair of DNA Double-Strand Breaks
• Histone H2AX regulates the formation of NBS1 foci on DNA damage sites
• Dissociation of ATM/NBS1 functions in telomere maintenance
• Bystander mutagenic effect of alpha particle in human-hamster hybrid cells
• Somatic Mutation Caused by Low Dose Rate Tritium Radiation : Studies Using A Hyper-sensitive DetectionSystem
• Complementation studies of immortalized cell lines from infants with total PCS
• Establishement of mouse Nbs1-deficient cell lines by gene targeting
• Association of cells from Fanconi anemia patients with radiation sensitivity
• Association of DNA repair protein NBS1 with telomere maintenance
• The function of NBS1 and histone H2AX in the early process of DNA repair.
• Reversed dose-rate effect of high LET radiation in mutation induction
• Chromosomal instability syndrome of total premature chromatid separation with mosaic variegated aneuploidy is defective in mitotic spindle checkpoint
• Screening of protein interacting with FANCG by Yeast two-hybrid system
• Functionally important domain analysis of the Nijimegen breakage syndrome gene. NBS1
• Development of a Radio-sensitive Mutation System for the Study of Dose Rate Effects of Space High LET Radiation
• NBS1, the Nijmegen breakage syndrome protein, regulates the localization of DNA repair complex hRAD50/hMRE11/NBS1
• Accelerated telomere shortening by disruption of DNA repair protein NBS1
• Construction of Nbs1 knockout cell line using chicken DT40
• Norepinephrine Enhances Radiosensitivity in Rat Ileal Epithelial Cells
• Nijmegen Breakage Syndrome (NBS) gene, NBS1, is involved in telomeric length maintenance.
• Loss of p53 -dependent signal transdution in γ -ray irradiated scid mouse fibroblasts
• Positional cloning of the gene for Nijmegen breakage syndrome
• Genetic Mapping of Nijmegen Breakage Syndrome using Functional Complementation Assays and Homozygosity Mapping
• Haplotype Analysis of Nijmegen Breakage Syndrome and Construction of Physical Map of Candidate Region.
• Complementation Assay between Radiation-Sensitive irs2 Mutant and Ataxia-Telangiectasia Cell
• The Genetic Homogeneity of Nijmegen Breakage Syndrome V1 and V2.
• Sensitivity to Ionizing Radiation in Saos-2 Cells Transfected with Mutant p53 Genes Depends on the Mutation Position
• Mutation-points of p53 affect the sensitivity of the cell to anticancer drugs.
• The sensitivity to ionizing radiation and radiation-induced apoptosis in Saos-2 cells transfected by four mutants and wild typc p53.
• How will a mutation of p53 affect the sensitivity of the cell to ionizing radiation.
• Mapping of the underlying gene for rare genetic complementation group Fanconi anemia
• NBS1 Regulates Apoptosis Induced by γ-Irradiation in Lymphoblastoid
• Mutation screening of the NBS1 gene in sporadic malignant lymphoma
• LET, cell cycle dependence for mutation induction and spectrum in HPRT locus
• Radiation-induced internal developmental abnormalities in scid mice
• Radiation-induced teratogenicity and embryo lethality in the scid mice.
• Cell growth and morphology of Dictyostelium discoideum in space environment
• Cell growth and morphology of Dictyostelium discoideum in space environment
• Mutation Analysis of the Fanconi Anemia Gene FAA in Japanese patients
• Mutation Analysis of the Fanconi Anemia Genes in Japanese Patients
• Function of NBS1 in Activation of ATM kinase in Response to IR.
• Protection by Polaprezinc Against Radiation-Induced Apoptosis in Rat Jejunal Crypt Cells
• Sucralfate Protects Intestinal Epithelial Cells from Radiation-Induced Apoptosis in Rats
• The Protective Effect of Fermented Milk Kefir on Radiation-induced Apoptosis in Colonic Crypt Cells of Rats
• The protective effect of a fermented milk Kefir to radiation-induced apoptosis in rat colon
• The suppression effect of sucralfate and soduim butyrate on radiation-induced apoptosis
• Heat sensitivity of DNA-dependent protein kinase activity
• The Role of the Sympathetic Nervous System in Radiation-induced Apoptosis in Jejunal Crypt Cells of Spontaneously Hypertensive Rats
• Acute Irradiation Injury and Autonomic Nervous System
• The genetic complementation assay of Nijmegen breakage syndrome witit ataxia telangiectasia on the basis of radiation sensitivity to cell killing.
• Development of Malignant Tumors following Irradiation for Preexisting Tumors:Study Based on Autopsy Cases of Double Cancer
• The phosphatidylinositol 3-kinase, inhibited by low dose of wortmannin, affects radiation sensitivity
• RBE for scid cells irradiated with high LET radiations
• Nijmegen breakage syndrome : Sequence analysis of an 800-kb genomic region on chromosome 8q21.
• A mutant human p53, 123A, which led to apoptosis but not Waf-1 in response to ionizing radiation in a human osteosarcoma cell line, Saos-2
• The scid factor on human chromosome 8 restores both V(D)J recombination and double-strand break repair
• The relationship between NBS1 and cell death induced by γ-ray irradiation in lymphoblastoid
• Cell cycle and LET dependence for 6-thioguanine-resistant mutation induced by heavy ion beam in mouse L5178Y cells
• Hypergravity Induces Phosphorylation of p53 at Serine 15, but not an Expression of p53-downstream Genes
• 128 Analysis of gene expression induced by hypergravity using DNA chip(Effects of space radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Accumulation and phosphorylation of p53 by hypergravity
• Hypergravity Modifies the Signal Transduction of Ionizing Radiation through p53
• Cross talk of p53 signal pathway by low dose radiation and artificial gravity
• Phosphorylation of p53 by low dose X-ray irradiation
• Recovery of heat inactivated DNA-PK activity and HSC73
• Recovery of heat inactivated DNA-PK activity and repair of DNA double strand break
• Efficient Trap of a Coaxial Gun Plasma in an Axisymmetric Mirror with an Internal Hoop
• Sensitivity of Heavy-Ion Beam in Scid Mouse Lung Fibroblast Cells.
• Thermosensitivity and DNA-PK activity of scid cells and hybrid scid cells containing human chromosome 8
• Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome
• Genetic heterogeneity of ataxia-telangiectasia-like hamster mutant irs2 with Nijmegen breakage syndrome.
• Quantification of radiation-induced aging using senescense accelerated mouse
• Reduction of gamma-ray components for Cf-252 fission neutron source.
• Norepinephrine Enhances Radiosensitivity in Rat Ileal Epithelial Cells
• Thermosensitivity and Thermotolerance of Scid Mouse Lung Fibroblast Cells.
• Effect of Low Dose Irradiation on the ConA Response of Mouse Splenic Lymphocytes
• Effect of Low Dose Irradiation on the ConA Response of Mouse Splenic Lymphocytes (II)
• Effects of Repeated Irradiation on a Biological Response with High Sensitivity to Exposure (IV)
• 3I1322 GFP融合技術を利用した昆虫培養細胞による組換えタンパク質分泌発現の評価系(3I 蛋白質_計測・解析の方法論2,日本生物物理学会第49回年会)

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