Evaluation of Hypoxia-specific Cytotoxic Bioreductive Agent-sodium Borocaptate-^<10>B Conjugates as ^<10>B-carriers in Boron Neutron Capture Therapy
スポンサーリンク
概要
- 論文の詳細を見る
- 2006-03-01
著者
-
小野 公二
京都大学原子炉実験所 粒子線腫瘍学研究センター
-
Suzuki Minoru
Particle Radiation Oncology Research Center Kyoto University
-
堀 均
Division Of Bioinformatics Engineering Department Of Life System Institute Of Technology And Science
-
堀 均
徳島大学 大学院ソシオテクノサイエンス研究部ライフシステム部門
-
MASUNAGA Shin-ichiro
Radiation Oncology Research Laboratory, Research Reactor Institute, Kyoto University
-
ONO Koji
Radiation Oncology Research Laboratory, Research Reactor Institute, Kyoto University
-
SAKURAI Yoshinori
Division of Radiation Life Science, Research Reactor Institute, Kyoto University
-
NAGASAWA Hideko
Departmet of Biological Science and Technology, Faculty of Engineering, University of Tokushima
-
UTO Yoshihiro
Departmet of Biological Science and Technology, Faculty of Engineering, University of Tokushima
-
HORI Hitoshi
Departmet of Biological Science and Technology, Faculty of Engineering, University of Tokushima
-
SUZUKI Minoru
Radiation Oncology Research Laboratory, Research Reactor Institute, Kyoto University
-
Suzuki M
Particle Radiation Oncology Research Center Kyoto University
-
Hosoi Hiroshi
Department Of Biological Science And Technology Faculty Of Engineering University Of Tokushima
-
木梨 友子
京都大学原子炉実験所附属粒子線腫瘍学研究センター
-
Sakurai Yoshinori
Research Reactor Institute Kyoto University
-
Sakurai Yoshinori
京都大学原子炉実験所
-
Maruhashi Akira
Research Reactor Institute Kyoto University
-
堀 均
徳島大学工学部
-
Ono Koji
Particle Radiation Oncology Research Center Kyoto University
-
Kinashi Yuko
Radiation Safety And Control Research Reactor Institute Kyoto University
-
NAGATA Kenji
Particle Radiation Oncology Research Centre, Research Reactor Institute, Kyoto University
-
GOTOH Keiko
Department of Biological Science and Technology, Faculty of Engineering, University of Tokushima
-
NAGATA Kenji
Radiation Oncology Research Laboratory, Kyoto University
-
MARUHASHI Akira
Division of Radiation Life Science, Kyoto University
-
KINASHI Yuko
Division of Radiation Safety, Research Reactor Institute, Kyoto University
-
Masunaga Shin-ichiro
Particle Radiation Oncology Research Center Kyoto University
-
永沢 秀子
岐阜薬科大学創薬化学大薬化学
-
永沢 秀子
徳島大学工学部
-
OKAICHI Kumio
Nara Med. Univ.
-
Miyata Shiro
Dep. Of Neurosurgery Osaka Medical Coll.
-
Nagata Kenji
Particle Radiation Oncology Research Centre Research Reactor Institute Kyoto University
-
Mori Sao
Lab. Radiat. Life Sci. Schi. Pharm. Sci. Nagasaki Univ.
-
Gotoh Keiko
Department Of Biological Science And Technology Faculty Of Engineering University Of Tokushima
-
Omori Katsunori
Institute Of Space And Astronautical Science Japan Aerospace Exploration Agency (jaxa)
-
Kinashi Yuko
Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University
-
Ono Koji
Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University
-
Hori Hitoshi
Division Of Bioinformatics Engineering Department Of Life System Institute Of Technology And Science
-
Hori Hitoshi
Department Of Biological Science And Technology Faculty Of Engineering University Of Tokushima
-
NAKANO KAZUSHIRO
The Institute of Physical and Chemical Research
-
Suzuki Masao
National Inst. Radiological Sci. Chiba Jpn
-
Suzuki Masao
Heavy-ion Radiobiology Res. Group National Inst. Radiological Sciences
-
Sakurai Y
Research Reactor Institute Kyoto University
-
Masunaga Shin-ichiro
Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University
-
Ono K
Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University
-
Kinashi Yuko
Kyoto Univ. Research Rcactor Institute
-
Uto Yoshihiro
Department Of Biological Science And Technology Faculty Of Engineering University Of Tokushima
-
Uto Yoshihiro
Division Of Bioinformatics Engineering Department Of Life System Institute Of Technology And Science
-
Nagasawa H
Department Of Biological Science And Technology Faculty Of Engineering University Of Tokushima
-
Nagasawa Hideko
Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima
-
Hori Hitoshi
Department Of Biochemistry And Molecular Biology Nippon Medical School
-
増永 慎一郎
Particle Radiation Oncology Res. Center Res. Reactor Inst. Kyoto Univ.
-
Matsumura Akira
Research Reactor Institute Kyoto University
-
Suzuki Minoru
Particle Oncology Research Center Research Reactor Institute Kyoto University
-
Ogura Koichi
College Of Industrial Technology Nihon University
-
Maruhashi Akira
Division Of Radiation Life Science Kyoto University
-
Uto Yoshihiro
Department Of Biological Science And Technology Faculty Of Engineering The University Of Tokushima
関連論文
- 4.最新放射線治療とその治療成績 : 放射線治療における外科治療の役割(PS1-1 悪性グリオーマ治療の進歩,プレナリーセッション,手術再考,第30回日本脳神経外科コングレス総会)
- Phosphorylated H2AX Foci in Tumor Cells Have No Correlation with Their Radiation Sensitivities
- DNA Damage Recognition Proteins Localize along Heavy Ion Induced Tracks in the Cell Nucleus
- LOH Analyses for Biological Effects of Space Radiation : Human Cell Culture in "Kibo" of International Space Station
- 鼻腔悪性黒色腫症例に対する硼素中性子捕捉療法
- DP-070-7 切除不能上縦隔悪性神経原性腫瘍に対しホウ素中性子捕捉療法が奏効した1治験例(第108回日本外科学会定期学術集会)
- 胸腺腫瘍に対する放射線治療成績
- 243 縦隔腫瘍の放射線治療成績
- シ-I-5 放射線治療の立場から
- 非小細胞性進行肺癌の放射線治療
- 前立腺癌に対する術中照射療法について : 前立腺癌治療上の諸問題
- P-352 新規抗がん剤TZT-1027の細胞周期の調節および放射線増感性について(分子生物学4, 第47回日本肺癌学会総会)
- The Effects of Boron Neutron Capture Therapy on Liver Tumors and Normal Hepatocytes in Mice
- The Combined Effect of Electroporation and Borocaptate in Boron Neutron Capture Therapy for Murine Solid Tumors
- Changes in the Sensitivity of Intratumor Cells during Fractionated Tirapazamine Administration
- Usefulness of Tirapazamine as a Combined Agent in Chemoradiation and Thermo-chemoradiation Therapy at Mild Temperatures: Reference to the Effect on Intratumor Quiescent Cells
- Effect of Electroporation on Cell Killing by Boron Neutron Capture Therapy Using Borocaptate Sodium (^B-BSH)
- Time-course Change in Oxygenation Status of Total and Quiescent Cell Populations in Solid Tumors after γ-ray Irradiation, Tirapazamine Injection or Cisplatin Treatment
- Chromosome Breakage and Cell Lethality in Human Hepatoma Cells Irradiated with X rays and Carbon-ion Beams
- 加速器中性子源によるホウ素中性子捕捉療法の展望 (特集 放射線治療の臨床応用)
- 新規抗がん剤TZT-1027の細胞周期に与える影響および放射線増感性についての検討
- 18. 新規抗癌剤TZT-1027の細胞周期への影響および放射線増感性(第84回 日本肺癌学会関西支部会,関西支部,支部活動)
- The First Life Science Experiments in ISS : Reports of "Rad Gene"-Space Radiation Effects on Human Cultured Cells-
- ホウ素中性子捕捉療法の皮膚線量低減と線量分布を改善する中性子照射技術の検討
- 中性子捕捉療法の線量評価
- 再発唾液腺腫瘍に対する新しい治療法
- トピックス講演 新たな段階に入った硼素中性子捕捉療法 (京都大学原子炉実験所第39回学術講演会 報文集)
- 硼素中性子捕捉療法新時代の到来
- 中性子捕捉療法の現状と将来
- 硼素中性子捕捉療法時の患部近傍での放射化の評価
- 頭頸部癌に対する硼素中性子捕捉療法 (京都大学原子炉実験所第42回学術講演会報文集)
- 癌放射線治療の新たなパラダイム : 硼素中性子捕捉療法(癌細胞選択的放射線治療)の現状と将来
- 放射線誘発バイスタンダー効果におけるDMSOの影響
- P075 放射線誘発バイスタンダー効果がDMSOにより抑制される機構(ポスターセッション)
- P047 X線照射された細胞での微小核形成とヒストンH2AXリン酸化フォーカス形成(ポスターセッション)
- W4-3 放射線誘発バイスタンダー効果がDMSOにより抑制される機構(ワークショップ(4) : 遺伝的不安定性と変異)
- ホウ素中性子捕捉療法(BNCT)の現状と将来の展開
- 固形腫瘍細胞特に放射線抵抗性休止期細胞の増感から見たTirapazamineの意義--腫瘍内低酸素領域の利用 (特集 第35回放射線による制癌シンポジウム--低LET放射線は生物学的手法の併用によって高LET放射線を超えられるか) -- (低酸素細胞の克服による増感)
- バイスタンダー効果の機構解析と今後の展望
- 再発頭頸部悪性腫瘍に対するホウ素中性子捕捉療法
- 頭頸部悪性腫瘍に対するBNCT後の経過と今後の展開 (平成14年度専門研究会報告書「中性子捕捉療法システムの高度化」)
- Recent Advances in the Biology of Heavy-Ion Cancer Therapy
- ATM is the Predominant Kinase Involved in the Phosphorylation of Histone H2AX after Heating
- γ-ray Irradiation Enhanced Boron-10 Compound Accumulation in Murine Tumors
- A Simple and Rapid Method for Measurement of ^B-para-Boronophenylalanine in the Blood for Boron Neutron Capture Therapy Using Fluorescence Spectrophotometry
- Boron Neutron Capture Therapy for Newly Diagnosed Glioblastoma
- Evaluation of Hypoxia-specific Cytotoxic Bioreductive Agent-sodium Borocaptate-^B Conjugates as ^B-carriers in Boron Neutron Capture Therapy
- S-4-4 From Regionally Selective Radiotherapy to Cellular Selective Radiotherapy(Aiming Further Development of Radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- 熱外中性子および集積機序の異なる二種類の硼素化合物を同時併用した悪性脳腫瘍に対する新規硼素中性子捕捉療法
- Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors : its Independency of p53 Status
- 癌のホウ素中性子捕捉療法--捕獲反応α粒子による細胞選択的放射線治療
- マイクロコンピューター支援による高精度コロニーアッセイ法を用いたSCCVII腫瘍に対する低酸素細胞増感剤の効果の検討
- 京大原子炉における悪性神経膠腫に対する硼素中性子捕捉療法
- Enhancement of Cisplatin Sensitivity of Quiescent Cells in Solid Tumors by Combined Treatment with Tirapazamine and Low-Temperature Hyperthermia
- 中性子捕捉療法のための熱中性子リアルタイムモニタの開発
- ホウ素中性子捕獲反応の利用が拓く基礎放射線腫瘍学研究の新局面 (京都大学原子炉実験所第45回学術講演会報文集)
- 悪性脳腫瘍に対する放射線療法 : 標準治療と最先端(悪性グリオーマ-機能温存と予後 (標準化治療法作成を目指して), PA-1 悪性脳腫瘍-標準化治療と治療抵抗例への挑戦, 第25回 日本脳神経外科コングレス総会)
- 適用拡大を目指した加速器ベースNCT照射システムの検討案
- SOF検出器によるBNCT治療中のリアルタイム熱中性子束評価 (平成14年度専門研究会報告書「中性子捕捉療法システムの高度化」)
- 京大炉(KUR)におけるこれまでの医療照射のまとめ (平成14年度専門研究会報告書「中性子捕捉療法システムの高度化」)
- BNCT用線量計画システム「SERA」の概要とKURにおける適用 (第37回京都大学原子炉実験所学術講演会)
- Inhibition of repair of radiation-induced damage by mild temperature hyperthermia, referring to the effect on quiescent cell populations
- Effective Suppression of Bystander Effects by DMSO Treatment of Irradiated CHO Cells
- Evaluation of Micronucleus Induction in Lymphocytes of Patients Following Boron-Neutron-Capture-Therapy : A Comparison with Thyroid Cancer Patients treated with radioiodine
- 84 Effects of Mild Temperature Hyperthermia and p53 Status of Tumor Cells on the Size of Hypoxic Cell Fractions in Solid Tumors(Radiation sensitivities in cells & tissues, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- Effects of p53 Status and Wortmannin Treatment on Potentially Lethal Damage Repair, with Emphasis on the Response of Intratumor Quiescent Cells
- Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors : its independence of p53 status
- Development of Selective Irradiation Method to Blood Vessel
- Mutation Induction in Cultured Human Cells after Low-dose and Low-dose-rate γ-ray Irradiation : Detection by LOH Analysis
- Induction of LOH events by Low-dose or Low-dose Rate Radiation Exposure
- Relative Biological Effectiveness of the 235 MeV Proton Beams at the National Cancer Center Hospital East
- Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells
- Extension of In vitro Life-span of γ-irradiated Human Embryo Cells Accompanied by Chromosome Instability
- Relative Biological Effectiveness of Accelerated Heavy Ions for Induction of Morphological Transformation in Syrian Hamster Embryo Cells
- Mitochondrial Function Modulates Cytoplasmic Irradiation Induced Bystander Effect
- Effects of Irradiated Medium on Chromatid Aberrations in Mammalian Cells Using Double Mylar Dishes
- 127 Effects of Irradiated Medium on Chromatid Aberrations in Mammalian Cells(Effects of space radiation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
- Induction of a Bystander Chromosomal Damage of He-ion microbeams in Mammalian Cells
- Bystander chromosomal alterations induced in mammalian cells using a charged particle microbeam.
- Growth and Cell Wall Properties in Hypocotyls of Arabidopsis tua6 Mutant under Microgravity Conditions in Space
- Delayed Induction of Telomere Instability in Normal Human Fibroblast Cells by Ionizing Radiation
- Mutation induction on normal human cells by split dose irradiation with carbon-ion beams
- Preparation and Outline of Space-Based Studies on Gravity Responses and Cell Wall Formation in Plants
- Germination and Growth Test in Four Strains of Arabidopsis thaliana in the Reference Model of European Modular Cultivation System
- Introduction to The Proposed Space Experiments Aboard The ISS Using The Silkworm, Bombyx mori
- Expression of p53-Regulated Genes in Cultured Mammalian Cells After Exposure to A Space Environment
- 熱中性子照射におけるDNA-PKcs阻害剤の生物学的効果
- ホウ素中性子捕捉療法後の末梢血リンパ球におけるマイクロヌクレウスの出現頻度の評価
- An Alternative Mechanism for Radioprotection by Dimethyl Sulfoxide; Possible Facilitation of DNA Double-strand Break Repair
- 中性子捕捉療法 (これだけは知っておきたい! 放射線療法Q&A--基本知識と最前線) -- (最新の放射線治療)
- DNA ligase IV is a potential molecular target in ACNU sensitivity
- 癌治療における併用療法としての低温度温熱処置の有用性について
- 温熱治療時における温度降下率の臨床的意義に関する検討
- マウス固形腫瘍に対する^Pt-CDDPを用いた温熱化学療法におけるニコチンアミドの付加的効果に関する考察
- 放射線・化学療法に対する静止期腫瘍細胞の反応 : 低温度温熱処置併用の意義
- BNCTによる悪性神経膠腫の治療成績
- BNCT用リアルタイムビームモニターに関する実験的研究
- ホウ素中性子捕捉療法
- 熱中性子照射におけるDNA-PKcs阻害剤の生物学的効果
- 放射線治療・粒子線治療と日本における医学物理士教育 : 第2回 ホウ素中性子捕捉療法(BNCT)