Increases in Gene-Targeting Frequencies Due to Disruption of kueA as a ku80 Homolog in Citric Acid-Producing Aspergillus niger

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概要

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• Low efficiencies of gene targeting hamper functional genomics in industrially important strains of Aspergillus niger. To generate strains showing high gene-targeting frequencies in A. niger WU-2223L producing citric acid, disruption of kueA encoding Ku80 homolog was performed. Disruption of kueA increased gene-targeting frequencies to 70%, and had no effect on citric acid production.

• 2011-08-23

著者

• Kirimura Kohtaro

  Department Of Applied Chemistry Faculty Of Science And Engineering Waseda University

• KOBAYASHI Keiichi

  Department of Applied Chemistry, Faculty of Science and Engineering, Waseda University

• Honda Yuki

  Department Of Applied Chemistry Faculty Of Science And Engineering Waseda University

• Kobayashi Keiichi

  Department Of Applied Chemistry Faculty Of Science And Engineering Waseda University

• Kobayashi Keiichi

  Department Of Anatomy Gunma University School Of Medicine

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