Increases in Gene-Targeting Frequencies Due to Disruption of kueA as a ku80 Homolog in Citric Acid-Producing Aspergillus niger
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概要
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Low efficiencies of gene targeting hamper functional genomics in industrially important strains of Aspergillus niger. To generate strains showing high gene-targeting frequencies in A. niger WU-2223L producing citric acid, disruption of kueA encoding Ku80 homolog was performed. Disruption of kueA increased gene-targeting frequencies to 70%, and had no effect on citric acid production.
- 2011-08-23
著者
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Kirimura Kohtaro
Department Of Applied Chemistry Faculty Of Science And Engineering Waseda University
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KOBAYASHI Keiichi
Department of Applied Chemistry, Faculty of Science and Engineering, Waseda University
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Honda Yuki
Department Of Applied Chemistry Faculty Of Science And Engineering Waseda University
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Kobayashi Keiichi
Department Of Applied Chemistry Faculty Of Science And Engineering Waseda University
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Kobayashi Keiichi
Department Of Anatomy Gunma University School Of Medicine
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