Characterization of Hybridization on Diamond Solution-Gate Field-Effect Transistors for Detecting Single Mismatched Oligonucleotides
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概要
- 論文の詳細を見る
Using diamond field-effect transistors (FETs) operated in electrolyte solution (solution-gate FETs; SGFETs), a label-free charge detection method between complementary and single mismatched target oligonucleotides is proposed. The probe oligonucleotides immobilized at the activated carboxyl groups of carboxylic aromatic compounds (CACs) on the previously formed amino groups of the diamond surface. The high performance of the diamond surface for oligonucleotides detection was studied with respect to selectivity, sensitivity, and reproducibility of the diamond SGFETs.
- Japan Society of Applied Physicsの論文
- 2008-11-25
著者
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Kawarada Hiroshi
School Of Science And Engineering Waseda University
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Kawarada Hiroshi
School Of Science & Engineering Waseda University
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SONG Kwang-Soup
School of Science and Engineering
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Yang Jung-hoon
School Of Science And Engineering Waseda University
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Song Kwang-soup
School Of Science And Engineering Waseda University
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Kuga Shouma
School of Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japa
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Kuga Shouma
School Of Science And Engineering Waseda University
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