Quenching Mechanism of Mechanically Compressed Green Fluorescent Protein Studied by CASSCF/AM1
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概要
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“Atomic force microscopy (AFM) compression simulation” approach together with “CASSCF/AM1 ONIOM” model calculation method is used for investigating the quenching mechanism of the luminescence in green fluorescent protein (GFP). Our results show that the electronic properties and steric conformations of the chromophore’s neighboring residues strongly influence the photo decay behaviors in GFP.
- 2006-09-25
著者
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Fujihira Masamichi
Department Of Biomolecular Engineering Tokyo Institute Of Technology
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Tsukada Masaru
Department of Nano-Science and Nano-Engineering, Waseda University, 513 Waseda Tsurumaki-cho, Shinjuku-ku, Tokyo 162-0041, Japan
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Gao Qi
Department of Biomolecular Engineering, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama 226-8501, Japan
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Tagami Katsuori
Department of Nanoscience, and Nanoengineering, Graduate School of Science and Engineering, Waseda University, 513 Waseda Tsurumaki-cho, Shinjuku-ku, Tokyo 162-0041, Japan
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