Preparation of A Serum-UA Control Material and Its Usefulness

概要

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1. A simple and convenient method for the preparation of UA -free and UA-known value control serum by removing UA in a pooled serum with activated charcoal and by dissolved critical amounts of UA in the UA-free serum is described. 2. For the complete removal of UA in a pooled serum with activated charcoal, stirring for 20 minutes at room temperature was needed. Clear UA-free serum like fresh serum was obtained by filtration through "Hyflo Super Cel" filtration aid under redused pressure. 3. The char coal treatment caused a significant change in levels of the following serum components: creatinine, bilirubin, calcium, potassium, and lipids. 4. The powder of the NBS-UA was completely dissolved in the UAfree serum after stirring for 30 to 60 minutes at room temperature. 5. The results of a small survay in Kanto and Tokai area showed that this UA-control materials were very useful aid for UA quality control in routine clinical laboratory.
Japanese Society of Gout and Nucleic Acid Metabolismの論文