Reduction by a model of NAD(P)H. 34. Substituent effect on asymmetric reduction of trifluoroacetophenones.
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概要
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Substituted and unsubstituted α,α,α-trifluoroacetophenones were reduced by a chiral NAD(P)H-model (<I>RR</I>-Me<SUB>2</SUB>PNPH). Both electron-releasing and -withdrawing substituents give better optical yields than unsubstitued compound. The result has been interpreted in terms of three-step mechanism which involves initial electron-transfer process.
- 公益社団法人 日本化学会の論文
著者
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Ohno Atsuyoshi
Institute For Chemical Research Kyoto Univ.
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Nakamura Kaoru
Institute For Chemical Research Kyoto University
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Oka Shinzaburo
Institute For Chemical Research Kyoto University
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Nakai Jun-ichi
Institute for Chemical Research, Kyoto University
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Goto Takehiko
Institute for Chemical Research, Kyoto University
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