NAD(P)H-NAD(P)+models. 74. Entropy-controlled kinetics, stereochemistry, and tunneling effect.
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概要
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Kinetics have been studied for the reactions of three NAD(P)H analogs and their 4-deuteriated compounds with 2,6-dichloro- and tetrachloro-1,4-benzoquinones. It has been elucidated that the entropy term occupies 50–90% of the Gibbs energy of activation at 298 K. Thus, the reaction is almost entropy-controlled. For certain combinations of the reducing and oxidizing reagents, quantum mechanical tunneling effect plays a large role to determine the reaction rate. The tunneling effect may be another measure of the stereochemistry.
- 公益社団法人 日本化学会の論文
著者
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Ohno Atsuyoshi
Institute For Chemical Research Kyoto Univ.
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MIKATA Yuji
Institute for Chemical Research, Kyoto University
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Kashiwagi Takeshi
Institute For Chemical Research Kyoto University
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Maruyama Tetsushi
Institute for Chemical Research, Kyoto University
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Goto Mutsuo
Institute for Chemical Research, Kyoto University
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