An improved resolution of .BETA.-hydroxy-DL-aspartic acid on optically active resin containing L-lysine or L-ornithine.
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概要
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A series of experiments on column chromatography of the optically active resin containing L-lysine or L-or nithine were carried out with pyridinium acetate and ammonium acetate solvent systems as the eluents. <I>threo</I>-β-liydroxy-DL-aspartic acid was found to be resolved on the optically active resin containing L-lysine with ammonium acetate solvent system; <I>erythro</I>-β-hydroxy-DL-aspartic acid could be resolved on that containing L-ornithine with pyridinium acetate solvent system. The <I>threo</I> or <I>erythro</I> racemate was resolved on a preparative scale, and the resolution including the complete characterization of enantiomers resolved was first accomplished.
- 公益社団法人 日本化学会の論文
著者
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Imai Hideo
Institute Of Pharmaceutical Sciences Fukuyama University
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Okai Hideo
Department Of Fermentation Technology Faculty Of Engineering Hiroshima University
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Kondo Seiji
Department Of Biochemistiy And Molecular Dentistry Okayama University Graduate School Of Medicine An
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Murai Shinji
Department af Chemical Technology Faculty of Engineering Osaka University
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Yoshida Hisanobu
Institute of Pharmaceutial Science, Hiroshima University School of Medicine
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Murai Shinji
Department of Fermentation Technology, Faculty of Engineering, Hiroshima University
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Anpeiji Shigeharu
Department of Fermentation Technology, Faculty of Engineering, Hiroshima University
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Toritani Yasunobu
Department of Fermentation Technology, Faculty of Engineering, Hiroshima University
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Kawada Kazunori
Department of Fermentation Technology, Faculty of Engineering, Hiroshima University
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Imai Hideo
Institute of Pharmaceutial Science, Hiroshima University School of Medicine
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