Chemical Studies on Tuberactinomycin. VII. Synthesis of γ-Hydroxy-β-lysine
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概要
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γ-Hydroxy-β-lysine is a new basic amino acid isolated from the hydrolyzates of antitubercular peptides, tuberactinomycin A and N. In order to confirm the structure and establish the stereochemistry of the amino acid, two diastereoisomers of γ-hydroxy-DL-β-lysine were synthesized by Arndt-Eistert synthesis <I>via</I> β-hiydroxyornithine. Synthetic <I>erythro</I> and <I>threo</I> isomers were found to be identical spectroscopically and chromatographically with the corresponding forms obtained from the antibiotics respectively.
- 公益社団法人 日本化学会の論文
著者
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Shiba Tetsuo
Department Of Chemistry Faculty Of Science Osaka University
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Wakamiya Tateaki
Department Of Chemistry Faculty Of Science Osaka University
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Kaneko Takeo
Department Of Cardiology National Fukuoka Higashi Medical Center
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Teshima Tadashi
Department Of Chemistry Faculty Of Science Osaka University
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Kubota Ichiro
Department of Chemistry, Faculty of Science, Osaka University
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