Synthetic Studies of Bacitracin. VI. Synthesis of Unprotected Thiazoline Peptides
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概要
- 論文の詳細を見る
For a total synthesis of bacitracian A, a synthetic method to secure unprotected thiazoline peptides must be established. 2-Aminomethyl-R-<I>Δ</I><SUP>2</SUP>-thiazoline-4-carboxamide, 2-aminomethyl-R-<I>Δ</I><SUP>2</SUP>-thiazoline-4-carboxylic acid, 2-aminomethyl-R-<I>Δ</I><SUP>2</SUP>-thiazoline-4-carbonyl-L-leucine were synthesized by either the iminoether coupling method or by the dehydration method using <I>N</I>-benzyloxycarbonyl group and benzyl ester as protecting groups.
- 公益社団法人 日本化学会の論文
著者
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Shiba Tetsuo
Department Of Chemistry Faculty Of Science Osaka University
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Kaneko Takeo
Department Of Cardiology National Fukuoka Higashi Medical Center
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Hirotsu Yoshihiro
Department of Chemistry, Faculty of Science, Osaka University
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